Gene description for P2RY2
Gene name
purinergic receptor P2Y, G-protein coupled, 2
Gene symbol
P2RY2
Other names/aliases
HP2U P2RU1 P2U P2U1 P2UR P2Y2 P2Y2R
Species
Homo sapiens
Database cross references - P2RY2
ExoCarta
ExoCarta_5029
Entrez Gene
5029
HGNC
8541
MIM
600041
UniProt
P41231
P2RY2 identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells
23333927
Ovarian cancer cells
23333927
Gene ontology annotations for P2RY2
Experiment description of studies that identified P2RY2 in exosomes
1
Experiment ID
211
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix
EV Cytosolic markers
✔
EpCAM|TFRC
EV Membrane markers
✔
cytochrome c|GOLGA2
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
IGROV1
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
2
Experiment ID
212
ISEV standards
✔
CEM
EV Biophysical techniques
✔
TSG101|Alix
EV Cytosolic markers
✔
EpCAM|TFRC
EV Membrane markers
✔
Cytochrome C|GOLGA2
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
OVCAR-3
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
Protein-protein interactions for P2RY2
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
ITGAV
3685
Invivo
Homo sapiens
Invitro
Homo sapiens
2
CD47
961
Affinity Capture-MS
Homo sapiens
Invivo
Homo sapiens
3
ITGB5
3693
Affinity Capture-MS
Homo sapiens
Invivo
Homo sapiens
Invitro
Homo sapiens
4
ITGB3
3690
Invivo
Homo sapiens
Invitro
Homo sapiens
View the network
image/svg+xml
Pathways in which P2RY2 is involved