Gene description for ATXN3
Gene name ataxin 3
Gene symbol ATXN3
Other names/aliases AT3
ATX3
JOS
MJD
MJD1
SCA3
Species Homo sapiens
 Database cross references - ATXN3
ExoCarta ExoCarta_4287
Vesiclepedia VP_4287
Entrez Gene 4287
HGNC 7106
MIM 607047
UniProt P54252  
 ATXN3 identified in exosomes derived from the following tissue/cell type
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
 Gene ontology annotations for ATXN3
Molecular Function
    cysteine-type deubiquitinase activity GO:0004843 IBA
    cysteine-type deubiquitinase activity GO:0004843 IDA
    cysteine-type deubiquitinase activity GO:0004843 ISS
    cysteine-type deubiquitinase activity GO:0004843 TAS
    protein binding GO:0005515 IPI
    ubiquitin protein ligase binding GO:0031625 IPI
    ubiquitin protein ligase binding GO:0031625 ISS
    identical protein binding GO:0042802 IPI
    ATPase binding GO:0051117 IPI
    K63-linked deubiquitinase activity GO:0061578 IDA
    K48-linked deubiquitinase activity GO:1990380 IDA
Biological Process
    microtubule cytoskeleton organization GO:0000226 IMP
    nucleotide-excision repair GO:0006289 TAS
    ubiquitin-dependent protein catabolic process GO:0006511 ISS
    protein quality control for misfolded or incompletely synthesized proteins GO:0006515 IBA
    protein quality control for misfolded or incompletely synthesized proteins GO:0006515 ISS
    chemical synaptic transmission GO:0007268 TAS
    nervous system development GO:0007399 TAS
    regulation of cell-substrate adhesion GO:0010810 IMP
    protein deubiquitination GO:0016579 TAS
    actin cytoskeleton organization GO:0030036 IMP
    cellular response to amino acid starvation GO:0034198 IDA
    cellular response to heat GO:0034605 ISS
    monoubiquitinated protein deubiquitination GO:0035520 ISS
    proteasome-mediated ubiquitin-dependent protein catabolic process GO:0043161 IBA
    proteasome-mediated ubiquitin-dependent protein catabolic process GO:0043161 ISS
    intermediate filament cytoskeleton organization GO:0045104 IMP
    protein K63-linked deubiquitination GO:0070536 IDA
    protein K48-linked deubiquitination GO:0071108 IDA
    cellular response to misfolded protein GO:0071218 ISS
    negative regulation of TORC1 signaling GO:1904262 IBA
    negative regulation of TORC1 signaling GO:1904262 IDA
    positive regulation of ERAD pathway GO:1904294 IBA
    positive regulation of ERAD pathway GO:1904294 IMP
    protein localization to cytosolic proteasome complex GO:1904327 IMP
    positive regulation of ubiquitin-dependent protein catabolic process GO:2000060 IDA
Subcellular Localization
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 IDA
    nucleoplasm GO:0005654 TAS
    nucleolus GO:0005730 IDA
    cytoplasm GO:0005737 TAS
    mitochondrial matrix GO:0005759 ISS
    lysosomal membrane GO:0005765 IDA
    endoplasmic reticulum membrane GO:0005789 IDA
    cytosol GO:0005829 IDA
    cytosol GO:0005829 TAS
    plasma membrane GO:0005886 IDA
    nuclear matrix GO:0016363 IEA
    mitochondrial membrane GO:0031966 ISS
    nuclear inclusion body GO:0042405 ISS
    synapse GO:0045202 IEA
 Experiment description of studies that identified ATXN3 in exosomes
1
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
3
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for ATXN3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 EIF3A 8661
Affinity Capture-MS Homo sapiens
2 UBL4A 8266
Affinity Capture-MS Homo sapiens
3 TK1 7083
Two-hybrid Homo sapiens
4 LDHB 3945
Affinity Capture-MS Homo sapiens
5 PKM 5315
Affinity Capture-MS Homo sapiens
6 ACOT9 23597
Affinity Capture-MS Homo sapiens
7 DNAJB2 3300
Affinity Capture-Western Homo sapiens
8 TEX11  
Two-hybrid Homo sapiens
9 UBA1 7317
Affinity Capture-MS Homo sapiens
10 TUBB8 347688
Affinity Capture-MS Homo sapiens
11 GPALPP1  
Affinity Capture-MS Homo sapiens
12 UBC 7316
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Co-crystal Structure Homo sapiens
Affinity Capture-MS Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Co-crystal Structure Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-crystal Structure Homo sapiens
13 CSE1L 1434
Affinity Capture-MS Homo sapiens
14 USP21  
Biochemical Activity Homo sapiens
15 PRPF40A 55660
Affinity Capture-MS Homo sapiens
16 GCN1L1 10985
Affinity Capture-MS Homo sapiens
17 SOX2  
Affinity Capture-MS Homo sapiens
18 KDELR1 10945
Affinity Capture-MS Homo sapiens
19 APEX1 328
Affinity Capture-RNA Homo sapiens
20 HDAC3 8841
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
21 DPM1 8813
Affinity Capture-MS Homo sapiens
22 DARS 1615
Affinity Capture-MS Homo sapiens
23 SF3B1 23451
Affinity Capture-MS Homo sapiens
24 TIMM23 100287932
Affinity Capture-MS Homo sapiens
25 PSMD12 5718
Affinity Capture-MS Homo sapiens
26 HSPH1 10808
Affinity Capture-MS Homo sapiens
27 PSMB6 5694
Affinity Capture-MS Homo sapiens
28 RPS9 6203
Affinity Capture-MS Homo sapiens
29 IGF2 3481
Affinity Capture-MS Homo sapiens
30 ARHGAP19  
Two-hybrid Homo sapiens
31 SNRPD3 6634
Affinity Capture-MS Homo sapiens
32 UBE2W  
Biochemical Activity Homo sapiens
33 PSMC1 5700
Affinity Capture-MS Homo sapiens
34 RNF126  
Affinity Capture-MS Homo sapiens
35 RAD23A 5886
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
36 BAG5 9529
Affinity Capture-MS Homo sapiens
37 ANXA7 310
Two-hybrid Homo sapiens
38 TCP1 6950
Affinity Capture-MS Homo sapiens
39 UBE4B 10277
Reconstituted Complex Homo sapiens
40 PSMA4 5685
Affinity Capture-MS Homo sapiens
41 PGAM5 192111
Affinity Capture-MS Homo sapiens
42 PSMD2 5708
Affinity Capture-MS Homo sapiens
43 MYH9 4627
Affinity Capture-MS Homo sapiens
44 ACTN4 81
Affinity Capture-MS Homo sapiens
45 CYC1 1537
Affinity Capture-MS Homo sapiens
46 ENO1 2023
Affinity Capture-MS Homo sapiens
47 DBT 1629
Affinity Capture-MS Homo sapiens
48 CAPN1 823
Biochemical Activity Homo sapiens
Protein-peptide Homo sapiens
49 TOMM20L  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
50 TRIM63  
Biochemical Activity Homo sapiens
51 SLC25A5 292
Affinity Capture-MS Homo sapiens
52 UBR2 23304
Affinity Capture-MS Homo sapiens
53 SSR4 6748
Affinity Capture-MS Homo sapiens
54 BIRC2  
Affinity Capture-MS Homo sapiens
55 HSPA5 3309
Affinity Capture-MS Homo sapiens
56 Tuba1a 64158
Affinity Capture-MS Rattus norvegicus
57 SDHA 6389
Affinity Capture-MS Homo sapiens
58 HSPE1 3336
Affinity Capture-MS Homo sapiens
59 BCAP31 10134
Affinity Capture-MS Homo sapiens
60 EEF1B2 1933
Affinity Capture-MS Homo sapiens
61 RBBP4 5928
Affinity Capture-MS Homo sapiens
62 SDC2 6383
Affinity Capture-MS Homo sapiens
63 TUBA4A 7277
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
64 PCBP1 5093
Affinity Capture-MS Homo sapiens
65 DND1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
66 RPA3 6119
Affinity Capture-MS Homo sapiens
67 NME1 4830
Affinity Capture-MS Homo sapiens
68 TMCO1 54499
Affinity Capture-MS Homo sapiens
69 DLST 1743
Affinity Capture-MS Homo sapiens
70 HSPA4 3308
Affinity Capture-MS Homo sapiens
71 PSMC5 5705
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
72 LAMA4 3910
Affinity Capture-MS Homo sapiens
73 PML 5371
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
74 LIG3 3980
Affinity Capture-Western Homo sapiens
75 PRKDC 5591
Affinity Capture-MS Homo sapiens
76 RPS16 6217
Affinity Capture-MS Homo sapiens
77 STUB1 10273
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
78 PSMB2 5690
Affinity Capture-MS Homo sapiens
79 RELA 5970
Affinity Capture-MS Homo sapiens
80 FASN 2194
Affinity Capture-MS Homo sapiens
81 PSAT1 29968
Affinity Capture-MS Homo sapiens
82 RBM25 58517
Affinity Capture-MS Homo sapiens
83 PCMT1 5110
Affinity Capture-MS Homo sapiens
84 CKB 1152
Affinity Capture-MS Homo sapiens
85 DCTN2 10540
Affinity Capture-MS Homo sapiens
86 TKT 7086
Affinity Capture-MS Homo sapiens
87 HSP90AA1 3320
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
88 SSBP1 6742
Affinity Capture-MS Homo sapiens
89 PSMA1 5682
Affinity Capture-MS Homo sapiens
90 DYNC1H1 1778
Affinity Capture-MS Homo sapiens
91 WWP2 11060
Biochemical Activity Homo sapiens
92 GAPDH 2597
Affinity Capture-MS Homo sapiens
93 PSMA5 5686
Affinity Capture-MS Homo sapiens
94 PSMC4 5704
Affinity Capture-MS Homo sapiens
95 PTCH1  
Affinity Capture-Western Homo sapiens
96 SEC61A1 29927
Affinity Capture-MS Homo sapiens
97 PSMA6 5687
Affinity Capture-MS Homo sapiens
98 HSP90AB2P 391634
Affinity Capture-MS Homo sapiens
99 SPRTN  
Affinity Capture-MS Homo sapiens
100 GART 2618
Affinity Capture-MS Homo sapiens
101 HSPA6 3310
Affinity Capture-MS Homo sapiens
102 USP13  
Affinity Capture-MS Homo sapiens
103 KCTD10 83892
Affinity Capture-MS Homo sapiens
104 RPA2 6118
Affinity Capture-MS Homo sapiens
105 HSP90AB1 3326
Affinity Capture-MS Homo sapiens
106 HSPB1 3315
Affinity Capture-MS Homo sapiens
107 NDUFA4 4697
Affinity Capture-MS Homo sapiens
108 SYVN1 84447
Affinity Capture-Western Homo sapiens
109 COPA 1314
Affinity Capture-MS Homo sapiens
110 RPS3 6188
Affinity Capture-MS Homo sapiens
111 NCOR1  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
112 PGK1 5230
Affinity Capture-MS Homo sapiens
113 OGDH 4967
Affinity Capture-MS Homo sapiens
114 ASIC1  
Two-hybrid Homo sapiens
115 NPM1 4869
Affinity Capture-MS Homo sapiens
116 ACTR1A 10121
Affinity Capture-MS Homo sapiens
117 PRDX2 7001
Affinity Capture-MS Homo sapiens
118 STIP1 10963
Affinity Capture-MS Homo sapiens
119 Ubr2 224826
Affinity Capture-Western Mus musculus
120 DNAJC7 7266
Affinity Capture-MS Homo sapiens
121 HAP1  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
122 DDX6 1656
Affinity Capture-MS Homo sapiens
123 TIMM50 92609
Affinity Capture-MS Homo sapiens
124 TMEM136  
Affinity Capture-MS Homo sapiens
125 USP7 7874
Affinity Capture-MS Homo sapiens
126 MAD2L1 4085
Affinity Capture-MS Homo sapiens
127 GSK3B 2932
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
128 CCT2 10576
Affinity Capture-MS Homo sapiens
129 GTF2I 2969
Affinity Capture-MS Homo sapiens
130 PFN1 5216
Affinity Capture-MS Homo sapiens
131 SLC1A5 6510
Affinity Capture-MS Homo sapiens
132 DSG1 1828
Affinity Capture-MS Homo sapiens
133 PRPF8 10594
Affinity Capture-MS Homo sapiens
134 CDKN1A  
Two-hybrid Homo sapiens
135 AMFR 267
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
136 PSMD14 10213
Affinity Capture-MS Homo sapiens
137 BAG6 7917
Affinity Capture-MS Homo sapiens
138 SNRNP200 23020
Affinity Capture-MS Homo sapiens
139 CCT6A 908
Affinity Capture-MS Homo sapiens
140 TUBA1C 84790
Affinity Capture-MS Homo sapiens
141 BCL7C  
Affinity Capture-MS Homo sapiens
142 S100A8 6279
Affinity Capture-MS Homo sapiens
143 HNRNPL 3191
Affinity Capture-MS Homo sapiens
144 IARS 3376
Affinity Capture-MS Homo sapiens
145 GET4 51608
Affinity Capture-MS Homo sapiens
146 LANCL1 10314
Affinity Capture-MS Homo sapiens
147 AIMP2 7965
Affinity Capture-MS Homo sapiens
148 TUBB 203068
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
149 ACLY 47
Affinity Capture-MS Homo sapiens
150 AIFM1 9131
Affinity Capture-MS Homo sapiens
151 CANX 821
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
152 RPS2 6187
Affinity Capture-MS Homo sapiens
153 XPO1 7514
Affinity Capture-MS Homo sapiens
154 UBE2L3 7332
Reconstituted Complex Homo sapiens
155 SLC25A22  
Affinity Capture-MS Homo sapiens
156 ATP5F1 515
Affinity Capture-MS Homo sapiens
157 TUBB4B 10383
Affinity Capture-MS Homo sapiens
158 LARS 51520
Affinity Capture-MS Homo sapiens
159 Cep152  
Affinity Capture-MS Mus musculus
160 EFTUD2 9343
Affinity Capture-MS Homo sapiens
161 RPS27 6232
Affinity Capture-MS Homo sapiens
162 ATP5J2 9551
Affinity Capture-MS Homo sapiens
163 SLC3A2 6520
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
164 DDB1 1642
Affinity Capture-MS Homo sapiens
165 Cntfr  
Affinity Capture-MS Rattus norvegicus
166 PSMB1 5689
Affinity Capture-MS Homo sapiens
167 TAF4 6874
Affinity Capture-Western Homo sapiens
168 HUWE1 10075
Affinity Capture-MS Homo sapiens
169 PHGDH 26227
Affinity Capture-MS Homo sapiens
170 DSP 1832
Affinity Capture-MS Homo sapiens
171 SLC25A3 5250
Affinity Capture-MS Homo sapiens
172 TFG 10342
Affinity Capture-MS Homo sapiens
173 TRAF2 7186
Affinity Capture-MS Homo sapiens
174 PARP1 142
Affinity Capture-MS Homo sapiens
175 TP53 7157
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
176 MKNK1  
Two-hybrid Homo sapiens
177 HDAC6 10013
Reconstituted Complex Homo sapiens
178 RPS12 6206
Affinity Capture-MS Homo sapiens
179 RPS4X 6191
Affinity Capture-MS Homo sapiens
180 SQSTM1 8878
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
181 HNRNPK 3190
Affinity Capture-MS Homo sapiens
182 EEF1D 1936
Affinity Capture-MS Homo sapiens
183 ATP1A1 476
Affinity Capture-MS Homo sapiens
184 PRDX1 5052
Affinity Capture-MS Homo sapiens
185 C1QBP 708
Affinity Capture-MS Homo sapiens
186 HSPA4L 22824
Affinity Capture-MS Homo sapiens
187 AEBP2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
188 PSMD1 5707
Affinity Capture-MS Homo sapiens
189 PSMD3 5709
Affinity Capture-MS Homo sapiens
190 RAD23B 5887
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
191 PRMT1 3276
Affinity Capture-MS Homo sapiens
192 HACD3 51495
Affinity Capture-MS Homo sapiens
193 EEF1G 1937
Affinity Capture-MS Homo sapiens
194 DLD 1738
Affinity Capture-MS Homo sapiens
195 YWHAE 7531
Affinity Capture-MS Homo sapiens
196 RPS19 6223
Affinity Capture-MS Homo sapiens
197 BYSL 705
Affinity Capture-MS Homo sapiens
198 ARCN1 372
Affinity Capture-MS Homo sapiens
199 SEMG2 6407
Affinity Capture-MS Homo sapiens
200 FOXO4  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
201 TRIM54  
Biochemical Activity Homo sapiens
202 ARHGDIA 396
Two-hybrid Homo sapiens
203 RUVBL1 8607
Affinity Capture-MS Homo sapiens
204 PJA1  
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
205 TRIM28 10155
Affinity Capture-MS Homo sapiens
206 PSRC1  
Affinity Capture-MS Homo sapiens
207 VARS 7407
Affinity Capture-MS Homo sapiens
208 IQGAP1 8826
Affinity Capture-MS Homo sapiens
209 ZNF460  
Affinity Capture-MS Homo sapiens
210 MDC1  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
211 EWSR1 2130
Two-hybrid Homo sapiens
212 PSMC2 5701
Affinity Capture-MS Homo sapiens
213 PDIA6 10130
Affinity Capture-MS Homo sapiens
214 PRDX4 10549
Affinity Capture-MS Homo sapiens
215 SNAP23 8773
Affinity Capture-MS Homo sapiens
216 CSNK2B 1460
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
217 HSPA8 3312
Affinity Capture-MS Homo sapiens
218 PXMP2  
Proximity Label-MS Homo sapiens
219 IRS4 8471
Affinity Capture-MS Homo sapiens
220 ATP5A1 498
Affinity Capture-MS Homo sapiens
221 PSMB4 5692
Affinity Capture-MS Homo sapiens
222 ASNA1 439
Affinity Capture-MS Homo sapiens
223 PARK2  
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Co-crystal Structure Homo sapiens
Affinity Capture-Western Homo sapiens
224 PNKP 11284
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
225 MARS 4141
Affinity Capture-MS Homo sapiens
226 TUBA1A 404053
Reconstituted Complex Bos taurus
227 TUBA1A 7846
Reconstituted Complex Homo sapiens
228 DIABLO 56616
Affinity Capture-MS Homo sapiens
229 ACACA 31
Affinity Capture-MS Homo sapiens
230 RAN 5901
Affinity Capture-MS Homo sapiens
231 TPI1 7167
Affinity Capture-MS Homo sapiens
232 DNAJA1 3301
Affinity Capture-MS Homo sapiens
233 RPN1 6184
Affinity Capture-MS Homo sapiens
234 UBE2D3 7323
Biochemical Activity Homo sapiens
235 TECR 9524
Affinity Capture-MS Homo sapiens
236 SF3A3 10946
Affinity Capture-MS Homo sapiens
237 IFITM5  
Affinity Capture-MS Homo sapiens
238 UBE2S  
Biochemical Activity Homo sapiens
239 PICK1  
Two-hybrid Homo sapiens
240 SF3B2 10992
Affinity Capture-MS Homo sapiens
241 AHCY 191
Affinity Capture-MS Homo sapiens
242 CNOT6  
Affinity Capture-MS Homo sapiens
243 BAG2 9532
Affinity Capture-MS Homo sapiens
244 Tubb4b 296554
Affinity Capture-MS Rattus norvegicus
245 EEF2 1938
Affinity Capture-MS Homo sapiens
246 NFKBIA  
Affinity Capture-MS Homo sapiens
247 TRAF6 7189
Biochemical Activity Homo sapiens
248 CCT4 10575
Affinity Capture-MS Homo sapiens
249 FAM195B 348262
Affinity Capture-MS Homo sapiens
250 POLR2A 5430
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
251 MGRN1 23295
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
252 PRPF19 27339
Affinity Capture-Western Homo sapiens
253 RPS13 6207
Affinity Capture-MS Homo sapiens
254 MCMBP 79892
Affinity Capture-MS Homo sapiens
255 RPS14 6208
Affinity Capture-MS Homo sapiens
256 RANBP1 5902
Affinity Capture-MS Homo sapiens
257 HAX1  
Affinity Capture-MS Homo sapiens
258 HSPD1 3329
Affinity Capture-MS Homo sapiens
259 HSPA9 3313
Affinity Capture-MS Homo sapiens
260 HLA-A 3105
Affinity Capture-MS Homo sapiens
261 XRCC5 7520
Affinity Capture-MS Homo sapiens
262 SUMO1 7341
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
263 PHB2 11331
Affinity Capture-MS Homo sapiens
264 CCT8 10694
Affinity Capture-MS Homo sapiens
265 SLC25A6 293
Affinity Capture-MS Homo sapiens
266 YTHDF2 51441
Affinity Capture-MS Homo sapiens
267 NDUFAF2  
Affinity Capture-MS Homo sapiens
268 KAT2B  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
269 RPA1 6117
Affinity Capture-MS Homo sapiens
270 HNRNPM 4670
Affinity Capture-MS Homo sapiens
271 LAMP2 3920
Affinity Capture-MS Homo sapiens
272 FANCI 55215
Affinity Capture-MS Homo sapiens
273 GRPEL1 80273
Affinity Capture-MS Homo sapiens
274 CREBBP  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
275 Tubb2b  
Affinity Capture-MS Rattus norvegicus
276 CCT7 10574
Affinity Capture-MS Homo sapiens
277 MIF 4282
Affinity Capture-MS Homo sapiens
278 RPL38 6169
Affinity Capture-MS Homo sapiens
279 FLNA 2316
Affinity Capture-MS Homo sapiens
280 C14orf166 51637
Affinity Capture-MS Homo sapiens
281 CYFIP1 23191
Affinity Capture-MS Homo sapiens
282 TMEM31  
Affinity Capture-MS Homo sapiens
283 RSF1  
Affinity Capture-MS Homo sapiens
284 ATXN3 4287
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Co-localization Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Co-localization Homo sapiens
Reconstituted Complex Homo sapiens
285 VIM 7431
Affinity Capture-MS Homo sapiens
286 EP300 2033
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
287 CAPN2 824
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
288 RPSA 3921
Affinity Capture-MS Homo sapiens
289 POLDIP3 84271
Affinity Capture-MS Homo sapiens
290 CCT3 7203
Affinity Capture-MS Homo sapiens
291 RPS3A 6189
Affinity Capture-MS Homo sapiens
292 PSMD6 9861
Affinity Capture-MS Homo sapiens
293 IPO7 10527
Affinity Capture-MS Homo sapiens
294 PSMD11 5717
Affinity Capture-MS Homo sapiens
295 KPNB1 3837
Affinity Capture-MS Homo sapiens
296 PAICS 10606
Affinity Capture-MS Homo sapiens
297 HSPA1L 3305
Affinity Capture-MS Homo sapiens
298 RPL15 6138
Affinity Capture-MS Homo sapiens
299 KARS 3735
Affinity Capture-MS Homo sapiens
300 PPIA 5478
Affinity Capture-MS Homo sapiens
301 TRIM55  
Biochemical Activity Homo sapiens
302 CFL1 1072
Affinity Capture-MS Homo sapiens
303 HSD17B12 51144
Affinity Capture-MS Homo sapiens
304 SNRPD2 6633
Affinity Capture-MS Homo sapiens
305 APP 351
Reconstituted Complex Homo sapiens
306 RFFL 117584
Biochemical Activity Homo sapiens
307 RPS20 6224
Affinity Capture-MS Homo sapiens
308 PRDX3 10935
Affinity Capture-MS Homo sapiens
309 PC 5091
Affinity Capture-MS Homo sapiens
310 ATXN2L 11273
Affinity Capture-MS Homo sapiens
311 IMPDH2 3615
Affinity Capture-MS Homo sapiens
312 OTUB2  
Affinity Capture-MS Homo sapiens
313 UBQLN1 29979
Reconstituted Complex Homo sapiens
314 ATP5O 539
Affinity Capture-MS Homo sapiens
315 ATP5C1 509
Affinity Capture-MS Homo sapiens
316 SRI 6717
Affinity Capture-MS Homo sapiens
317 NGLY1 55768
Affinity Capture-MS Homo sapiens
318 PSMC6 5706
Affinity Capture-MS Homo sapiens
319 FAF2 23197
Affinity Capture-MS Homo sapiens
320 SARS 6301
Affinity Capture-MS Homo sapiens
321 PSMC3 5702
Affinity Capture-MS Homo sapiens
322 LSM12 124801
Affinity Capture-MS Homo sapiens
323 PSMD4 5710
Affinity Capture-MS Homo sapiens
324 HSP90B1 7184
Affinity Capture-MS Homo sapiens
325 NONO 4841
Affinity Capture-MS Homo sapiens
326 CCT5 22948
Affinity Capture-MS Homo sapiens
327 HTT 3064
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
328 VCP 7415
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Reconstituted Complex Homo sapiens
Co-crystal Structure Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
329 Pafah1b1 18472
Affinity Capture-MS Mus musculus
330 TUBB2B  
Reconstituted Complex Bos taurus
331 SF3B6 51639
Affinity Capture-MS Homo sapiens
332 WDR87  
Affinity Capture-MS Homo sapiens
333 GANAB 23193
Affinity Capture-MS Homo sapiens
334 MYH10 4628
Affinity Capture-MS Homo sapiens
335 KRT2 3849
Affinity Capture-MS Homo sapiens
336 DNM2 1785
Two-hybrid Homo sapiens
337 ITCH 83737
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
338 RPS15A 6210
Affinity Capture-MS Homo sapiens
339 ENAH 55740
Affinity Capture-MS Homo sapiens
340 Aff1  
Affinity Capture-MS Mus musculus
341 ATP5B 506
Affinity Capture-MS Homo sapiens
342 RPS6KA1 6195
Two-hybrid Homo sapiens
343 BAG3 9531
Affinity Capture-Luminescence Homo sapiens
344 PHB 5245
Affinity Capture-MS Homo sapiens
345 ACTN1 87
Affinity Capture-MS Homo sapiens
346 SFPQ 6421
Affinity Capture-MS Homo sapiens
347 HAGH 3029
Affinity Capture-MS Homo sapiens
348 EIF4G1 1981
Affinity Capture-MS Homo sapiens
349 C16orf70  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
350 PSMD13 5719
Affinity Capture-MS Homo sapiens
351 NCKAP1 10787
Affinity Capture-MS Homo sapiens
352 CAMSAP3  
Affinity Capture-MS Homo sapiens
353 C2orf47  
Affinity Capture-MS Homo sapiens
354 RPS6 6194
Affinity Capture-MS Homo sapiens
355 MAP3K1 4214
Biochemical Activity Homo sapiens
356 NAP1L1 4673
Affinity Capture-MS Homo sapiens
357 PSMD7 5713
Affinity Capture-MS Homo sapiens
358 POMZP3  
Affinity Capture-MS Homo sapiens
359 EPRS 2058
Affinity Capture-MS Homo sapiens
360 PSMB5 5693
Affinity Capture-MS Homo sapiens
361 MFN2 9927
Proximity Label-MS Homo sapiens
362 SF3B3 23450
Affinity Capture-MS Homo sapiens
363 CLTC 1213
Affinity Capture-MS Homo sapiens
364 AMOT  
Affinity Capture-MS Homo sapiens
365 HNRNPU 3192
Affinity Capture-MS Homo sapiens
366 SLC25A11 8402
Affinity Capture-MS Homo sapiens
367 CASP7  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
368 DNAJA2 10294
Affinity Capture-MS Homo sapiens
369 NUFIP2 57532
Affinity Capture-MS Homo sapiens
370 HNRNPA2B1 3181
Affinity Capture-MS Homo sapiens
371 DNAJA3 9093
Affinity Capture-MS Homo sapiens
372 SMURF1 57154
Biochemical Activity Homo sapiens
373 CREB1  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
374 TUBB4A 10382
Affinity Capture-MS Homo sapiens
375 TXN 7295
Affinity Capture-MS Homo sapiens
376 MAGED1 9500
Affinity Capture-MS Homo sapiens
377 CAD 790
Affinity Capture-MS Homo sapiens
378 RPL23 9349
Affinity Capture-MS Homo sapiens
379 TCAF1 9747
Affinity Capture-MS Homo sapiens
380 RPS8 6202
Affinity Capture-MS Homo sapiens
381 XRCC6 2547
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
382 RARS 5917
Affinity Capture-MS Homo sapiens
383 GNB2L1 10399
Affinity Capture-MS Homo sapiens
384 NEDD8 4738
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
385 ALDOA 226
Affinity Capture-MS Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here