Gene description for PNMA5
Gene name paraneoplastic Ma antigen family member 5
Gene symbol PNMA5
Other names/aliases -
Species Homo sapiens
 Database cross references - PNMA5
ExoCarta ExoCarta_114824
Vesiclepedia VP_114824
Entrez Gene 114824
HGNC 18743
MIM 300916
UniProt Q96PV4  
 PNMA5 identified in exosomes derived from the following tissue/cell type
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
 Gene ontology annotations for PNMA5
Molecular Function
    protein binding GO:0005515 IPI
    identical protein binding GO:0042802 IPI
Biological Process
    positive regulation of apoptotic process GO:0043065 ISS
 Experiment description of studies that identified PNMA5 in exosomes
1
Experiment ID 363
MISEV standards
Biophysical techniques
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
DCLK1
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 364
MISEV standards
Biophysical techniques
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
DCLK1
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
3
Experiment ID 365
MISEV standards
Biophysical techniques
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
DCLK1
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for PNMA5
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 DDX6 1656
Two-hybrid Homo sapiens
2 FOXH1  
Two-hybrid Homo sapiens
3 PRKAA1 5562
Two-hybrid Homo sapiens
4 FSD2 123722
Two-hybrid Homo sapiens
5 CEP57L1  
Two-hybrid Homo sapiens
6 C11orf49  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
7 CARD9 64170
Two-hybrid Homo sapiens
8 GYS1 2997
Two-hybrid Homo sapiens
9 GRB2 2885
Two-hybrid Homo sapiens
10 VPS28 51160
Two-hybrid Homo sapiens
11 CCNC  
Two-hybrid Homo sapiens
12 BHLHB9 80823
Two-hybrid Homo sapiens
13 KIFC3 3801
Two-hybrid Homo sapiens
14 GOLGA6L9  
Two-hybrid Homo sapiens
15 POLR3C 10623
Two-hybrid Homo sapiens
16 ARPC4 10093
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
17 MYO15B 80022
Two-hybrid Homo sapiens
18 EHHADH 1962
Two-hybrid Homo sapiens
19 CETN2 1069
Two-hybrid Homo sapiens
20 RAD23B 5887
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
21 ZMYND19  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
22 AP1M1 8907
Two-hybrid Homo sapiens
23 TXNL4B  
Two-hybrid Homo sapiens
24 CDC23 8697
Two-hybrid Homo sapiens
25 KPNA2 3838
Two-hybrid Homo sapiens
26 HOOK3 84376
Two-hybrid Homo sapiens
27 PNMA1 9240
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
28 GLIPR2 152007
Two-hybrid Homo sapiens
29 UACA 55075
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
30 CCDC102B  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
31 TTC23  
Two-hybrid Homo sapiens
32 CADPS  
Two-hybrid Homo sapiens
33 PSMA1 5682
Two-hybrid Homo sapiens
34 GAS8  
Two-hybrid Homo sapiens
35 DZIP1L  
Two-hybrid Homo sapiens
36 PNMA5 114824
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
37 PAX5  
Two-hybrid Homo sapiens
38 ZBTB8A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
39 TBC1D22B  
Two-hybrid Homo sapiens
40 MAGED1 9500
Two-hybrid Homo sapiens
41 TNPO2 30000
Two-hybrid Homo sapiens
42 MOAP1  
Two-hybrid Homo sapiens
43 WDYHV1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
44 TCEANC  
Two-hybrid Homo sapiens
45 GORASP2 26003
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
46 LHX3  
Two-hybrid Homo sapiens
47 GTF3C2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
48 ZBTB25  
Two-hybrid Homo sapiens
49 SORBS3 10174
Two-hybrid Homo sapiens
50 CTNNA3  
Two-hybrid Homo sapiens
51 GTF3C1  
Affinity Capture-MS Homo sapiens
52 SH3KBP1 30011
Two-hybrid Homo sapiens
53 CRACR2A  
Two-hybrid Homo sapiens
54 HSF2BP  
Two-hybrid Homo sapiens
55 VIM 7431
Two-hybrid Homo sapiens
56 ZFYVE26 23503
Two-hybrid Homo sapiens
57 UBASH3A 53347
Two-hybrid Homo sapiens
58 TCEA2  
Two-hybrid Homo sapiens
59 C9orf41  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
60 APPL1 26060
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which PNMA5 is involved
No pathways found





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