Gene description for DVL2
Gene name	dishevelled segment polarity protein 2
Gene symbol	DVL2
Other names/aliases	-
Species	Homo sapiens
Database cross references - DVL2
ExoCarta	ExoCarta_1856
Entrez Gene	1856
HGNC	3086
MIM	602151
UniProt	O14641
DVL2 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells	26054723

Gene ontology annotations for DVL2

Molecular Function     protein binding GO:0005515 IPI     protein self-association GO:0043621 IEA     protein domain specific binding GO:0019904 IEA     identical protein binding GO:0042802 IPI     frizzled binding GO:0005109 IPI Biological Process     segment specification GO:0007379 ISS     positive regulation of protein tyrosine kinase activity GO:0061098 IEA     neural tube closure GO:0001843 ISS     heart development GO:0007507 ISS     convergent extension involved in neural plate elongation GO:0022007 IEA     small GTPase mediated signal transduction GO:0007264 TAS     positive regulation of JUN kinase activity GO:0043507 IMP     positive regulation of transcription, DNA-templated GO:0045893 IDA     outflow tract morphogenesis GO:0003151 ISS     planar cell polarity pathway involved in neural tube closure GO:0090179 IBA     cochlea morphogenesis GO:0090103 IEA     negative regulation of canonical Wnt signaling pathway GO:0090090 TAS     non-canonical Wnt signaling pathway GO:0035567 IMP     positive regulation of canonical Wnt signaling pathway GO:0090263 TAS     positive regulation of sequence-specific DNA binding transcription factor activity GO:0051091 IDA     hippo signaling GO:0035329 TAS     canonical Wnt signaling pathway involved in regulation of cell proliferation GO:0044340 IDA     positive regulation of protein phosphorylation GO:0001934 IMP     canonical Wnt signaling pathway GO:0060070 IDA     Wnt signaling pathway GO:0016055 IGI     cellular protein localization GO:0034613 IEA     transcription from RNA polymerase II promoter GO:0006366 IDA     Wnt signaling pathway, planar cell polarity pathway GO:0060071 IDA Subcellular Localization     cytosol GO:0005829 TAS     cytoplasm GO:0005737 IDA     apical part of cell GO:0045177 IEA     nucleus GO:0005634 ISS     clathrin-coated endocytic vesicle GO:0045334 TAS     plasma membrane GO:0005886 IEA     cytoplasmic vesicle GO:0031410 IDA