Gene description for CNOT7
Gene name	CCR4-NOT transcription complex, subunit 7
Gene symbol	CNOT7
Other names/aliases	CAF1 Caf1a hCAF-1
Species	Homo sapiens
Database cross references - CNOT7
ExoCarta	ExoCarta_29883
Entrez Gene	29883
HGNC	14101
MIM	604913
UniProt	Q9UIV1
CNOT7 identified in exosomes derived from the following tissue/cell type
Thymus	23844026

Gene ontology annotations for CNOT7

Molecular Function     protein binding GO:0005515 IPI     poly(A)-specific ribonuclease activity GO:0004535 IDA     exoribonuclease activity GO:0004532 IDA     sequence-specific DNA binding transcription factor activity GO:0003700 TAS     RNA binding GO:0003723 IEA     3'-5'-exoribonuclease activity GO:0000175 IDA     metal ion binding GO:0046872 IEA     signal transducer activity GO:0004871 TAS Biological Process     RNA phosphodiester bond hydrolysis, exonucleolytic GO:0090503 IEA     positive regulation of nuclear-transcribed mRNA poly(A) tail shortening GO:0060213 IMP     signal transduction GO:0007165 TAS     cytoplasmic mRNA processing body assembly GO:0033962 IEA     negative regulation of gene expression GO:0010629 IMP     gene silencing by miRNA GO:0035195 TAS     deadenylation-dependent decapping of nuclear-transcribed mRNA GO:0000290 IEA     gene silencing by RNA GO:0031047 ISS     positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:1900153 IMP     positive regulation of transcription from RNA polymerase II promoter GO:0045944 IEA     transcription, DNA-templated GO:0006351 IEA     negative regulation of cell proliferation GO:0008285 IDA     gene expression GO:0010467 TAS     nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 TAS     nuclear-transcribed mRNA poly(A) tail shortening GO:0000289 TAS     exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay GO:0043928 IDA     regulation of translation GO:0006417 IEA     positive regulation of mRNA catabolic process GO:0061014 IMP     carbohydrate metabolic process GO:0005975 TAS     positive regulation of cell proliferation GO:0008284 IMP Subcellular Localization     membrane GO:0016020 IDA     cytosol GO:0005829 TAS     cytoplasmic mRNA processing body GO:0000932 ISS     nucleus GO:0005634 IDA     CCR4-NOT complex GO:0030014 NAS