Gene ontology annotations for COPS6
Experiment description of studies that identified COPS6 in exosomes
1
Experiment ID
207
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|HSP70
EV Cytosolic markers
✔
FLOT1
EV Membrane markers
✔
VDAC
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23161513
Organism
Homo sapiens
Experiment description
Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors
Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ.
Journal name
Mol Cell Proteomics
Publication year
2012
Sample
Colorectal cancer cells
Sample name
DKO-1
Isolation/purification methods
Differential centrifugation Filtration
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
2
Experiment ID
208
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|HSP70
EV Cytosolic markers
✔
FLOT1
EV Membrane markers
✔
VDAC
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23161513
Organism
Homo sapiens
Experiment description
Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors
Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ.
Journal name
Mol Cell Proteomics
Publication year
2012
Sample
Colorectal cancer cells
Sample name
Dks-8
Isolation/purification methods
Differential centrifugation Filtration
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
3
Experiment ID
209
ISEV standards
✘
EV Biophysical techniques
✔
TSG101|HSP70
EV Cytosolic markers
✔
FLOT1
EV Membrane markers
✔
VDAC
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23161513
Organism
Homo sapiens
Experiment description
Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors
Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ.
Journal name
Mol Cell Proteomics
Publication year
2012
Sample
Colorectal cancer cells
Sample name
DLD-1
Isolation/purification methods
Differential centrifugation Filtration
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
4
Experiment ID
211
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix
EV Cytosolic markers
✔
EpCAM|TFRC
EV Membrane markers
✔
cytochrome c|GOLGA2
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
IGROV1
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
5
Experiment ID
212
ISEV standards
✔
CEM
EV Biophysical techniques
✔
TSG101|Alix
EV Cytosolic markers
✔
EpCAM|TFRC
EV Membrane markers
✔
Cytochrome C|GOLGA2
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
OVCAR-3
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
Protein-protein interactions for COPS6
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
PBX2
Affinity Capture-MS
Homo sapiens
2
COPS8
10920
Co-purification
Homo sapiens
3
CDH10
Two-hybrid
Homo sapiens
4
ROGDI
79641
Two-hybrid
Homo sapiens
5
DLEU1
Two-hybrid
Homo sapiens
6
TRDMT1
Two-hybrid
Homo sapiens
7
PRKRA
8575
Two-hybrid
Homo sapiens
8
COX17
Two-hybrid
Homo sapiens
9
ZNF24
Two-hybrid
Homo sapiens
10
EMD
Two-hybrid
Homo sapiens
11
PSAP
5660
Two-hybrid
Homo sapiens
12
SMN1
6606
Two-hybrid
Homo sapiens
13
LAMA4
3910
Two-hybrid
Homo sapiens
14
SULT1E1
Two-hybrid
Homo sapiens
15
TK1
7083
Two-hybrid
Homo sapiens
16
COX5A
Two-hybrid
Homo sapiens
17
PAEP
Two-hybrid
Homo sapiens
18
CRELD1
Two-hybrid
Homo sapiens
19
C7orf19
Two-hybrid
Homo sapiens
20
ERH
2079
Two-hybrid
Homo sapiens
21
ZFHX1B
Two-hybrid
Homo sapiens
22
PSMD11
5717
Two-hybrid
Homo sapiens
23
EDN1
Two-hybrid
Homo sapiens
24
HMOX2
3163
Two-hybrid
Homo sapiens
25
HSU79303
Two-hybrid
Homo sapiens
26
SLC2A1
6513
Two-hybrid
Homo sapiens
27
RPL15
6138
Two-hybrid
Homo sapiens
28
SAT
Two-hybrid
Homo sapiens
29
S100A10
6281
Two-hybrid
Homo sapiens
30
RFC5
5985
Two-hybrid
Homo sapiens
31
SERPINB9
5272
Two-hybrid
Homo sapiens
32
FAU
Two-hybrid
Homo sapiens
33
PMF1
Two-hybrid
Homo sapiens
34
DIS3L2
129563
Two-hybrid
Homo sapiens
35
FLJ10350
Two-hybrid
Homo sapiens
36
BTBD2
Two-hybrid
Homo sapiens
37
PHYHIP
9796
Two-hybrid
Homo sapiens
38
PFKL
5211
Two-hybrid
Homo sapiens
39
C1orf174
Two-hybrid
Homo sapiens
40
MNAT1
Two-hybrid
Homo sapiens
41
RPA2
6118
Two-hybrid
Homo sapiens
42
STK40
Two-hybrid
Homo sapiens
43
PAFAH1B3
5050
Two-hybrid
Homo sapiens
44
PTEN
Two-hybrid
Homo sapiens
45
SNRPG
6637
Two-hybrid
Homo sapiens
46
TRIB3
Two-hybrid
Homo sapiens
47
PDZK1IP1
10158
Two-hybrid
Homo sapiens
48
STX5A
Two-hybrid
Homo sapiens
49
QTRT1
81890
Two-hybrid
Homo sapiens
50
TDGF1
Two-hybrid
Homo sapiens
51
SERPINA5
5104
Two-hybrid
Homo sapiens
52
C4orf17
Two-hybrid
Homo sapiens
53
LPL
4023
Two-hybrid
Homo sapiens
54
MYCBP
Two-hybrid
Homo sapiens
55
EIF3E
3646
Two-hybrid
Homo sapiens
Affinity Capture-Western
Homo sapiens
56
WIPI-2
Two-hybrid
Homo sapiens
57
RAB27A
5873
Two-hybrid
Homo sapiens
58
CDKN2C
Two-hybrid
Homo sapiens
59
EP300
2033
Two-hybrid
Homo sapiens
View the network
image/svg+xml
Pathways in which COPS6 is involved
No pathways found