Gene description for RRP7A
Gene name ribosomal RNA processing 7 homolog A (S. cerevisiae)
Gene symbol RRP7A
Other names/aliases BK126B4.3
CGI-96
Species Homo sapiens
 Database cross references - RRP7A
ExoCarta ExoCarta_27341
Vesiclepedia VP_27341
Entrez Gene 27341
HGNC 24286
UniProt Q9Y3A4  
 RRP7A identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for RRP7A
Molecular Function
    RNA binding GO:0003723 HDA
    protein binding GO:0005515 IPI
Biological Process
    ribosomal small subunit assembly GO:0000028 IBA
    blastocyst formation GO:0001825 IEA
    rRNA processing GO:0006364 IBA
    rRNA processing GO:0006364 IMP
    ribosome biogenesis GO:0042254 IMP
    ribosomal small subunit biogenesis GO:0042274 IDA
    cilium disassembly GO:0061523 IMP
    protein localization to nucleolus GO:1902570 IMP
Subcellular Localization
    nucleoplasm GO:0005654 TAS
    nucleolus GO:0005730 IDA
    cytoplasm GO:0005737 IEA
    centrosome GO:0005813 IDA
    cilium GO:0005929 IDA
    small-subunit processome GO:0032040 IDA
    CURI complex GO:0032545 IBA
    UTP-C complex GO:0034456 IBA
 Experiment description of studies that identified RRP7A in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for RRP7A
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HNRNPH1 3187
Affinity Capture-RNA Homo sapiens
2 SLFN11 91607
Affinity Capture-MS Homo sapiens
3 H2AFJ 55766
Affinity Capture-MS Homo sapiens
4 UBE2H 7328
Affinity Capture-MS Homo sapiens
5 HNRNPC 3183
Co-fractionation Homo sapiens
6 KIF18A  
Affinity Capture-MS Homo sapiens
7 GADD45G  
Two-hybrid Homo sapiens
8 ANAPC15  
Affinity Capture-MS Homo sapiens
9 RPS3 6188
Affinity Capture-MS Homo sapiens
10 ARMC7  
Two-hybrid Homo sapiens
11 USP36  
Affinity Capture-MS Homo sapiens
12 RPS20 6224
Co-fractionation Homo sapiens
13 DPYSL2 1808
Affinity Capture-MS Homo sapiens
14 NOLC1 9221
Co-fractionation Homo sapiens
15 RPL24 6152
Co-fractionation Homo sapiens
16 ANOS1 3730
Affinity Capture-MS Homo sapiens
17 TFIP11  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
18 HIST2H3PS2 440686
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 CRMP1 1400
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 U2AF1 7307
Co-fractionation Homo sapiens
21 SERF2 10169
Affinity Capture-MS Homo sapiens
22 MECP2 4204
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
23 MYCN  
Affinity Capture-MS Homo sapiens
24 RPS11 6205
Affinity Capture-MS Homo sapiens
25 NCSTN 23385
Co-fractionation Homo sapiens
26 AURKA 6790
Affinity Capture-MS Homo sapiens
27 CAMK2A 815
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
28 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
29 DDX21 9188
Co-fractionation Homo sapiens
30 RPL9 6133
Co-fractionation Homo sapiens
31 RPL4 6124
Affinity Capture-MS Homo sapiens
32 UPF2 26019
Two-hybrid Homo sapiens
33 RPS10 6204
Co-fractionation Homo sapiens
34 ACIN1 22985
Co-fractionation Homo sapiens
35 SRSF6 6431
Affinity Capture-MS Homo sapiens
36 ZBTB48  
Affinity Capture-MS Homo sapiens
37 RPL18A 6142
Affinity Capture-MS Homo sapiens
38 MAPT  
Affinity Capture-MS Homo sapiens
39 NFIA 4774
Co-fractionation Homo sapiens
40 RPL31 6160
Proximity Label-MS Homo sapiens
41 U2AF2 11338
Co-fractionation Homo sapiens
42 ATP4A 495
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
43 HECTD1 25831
Affinity Capture-MS Homo sapiens
44 RPLP0 6175
Co-fractionation Homo sapiens
45 LRRC46  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
46 MYBBP1A 10514
Co-fractionation Homo sapiens
47 C1orf189  
Affinity Capture-MS Homo sapiens
48 WDR46  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
49 RBM39 9584
Co-fractionation Homo sapiens
50 S100P 6286
Affinity Capture-MS Homo sapiens
51 ABT1 29777
Affinity Capture-MS Homo sapiens
52 TPR 7175
Co-fractionation Homo sapiens
53 SIRT7  
Affinity Capture-MS Homo sapiens
54 STXBP1 6812
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
55 NR3C1 2908
Proximity Label-MS Homo sapiens
56 EBNA1BP2 10969
Co-fractionation Homo sapiens
57 PDCD11 22984
Affinity Capture-MS Homo sapiens
58 GNG2 54331
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
59 ZNF512  
Affinity Capture-MS Homo sapiens
60 MAPK6  
Two-hybrid Homo sapiens
61 ZNF692  
Affinity Capture-MS Homo sapiens
62 NHP2L1 4809
Co-fractionation Homo sapiens
63 HP1BP3 50809
Co-fractionation Homo sapiens
64 MATR3 9782
Co-fractionation Homo sapiens
65 RPL18 6141
Affinity Capture-MS Homo sapiens
66 RNF2  
Affinity Capture-MS Homo sapiens
67 BEND3  
Affinity Capture-MS Homo sapiens
68 H2AFB2  
Affinity Capture-MS Homo sapiens
69 DPYSL3 1809
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
70 NOL6 65083
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
71 GNL3 26354
Co-fractionation Homo sapiens
72 EHBP1L1 254102
Affinity Capture-MS Homo sapiens
73 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
74 CIT 11113
Affinity Capture-MS Homo sapiens
75 MNDA 4332
Affinity Capture-MS Homo sapiens
76 CDCA7L  
Two-hybrid Homo sapiens
77 HNRNPM 4670
Co-fractionation Homo sapiens
78 UTP23  
Reconstituted Complex Homo sapiens
79 RPS5 6193
Co-fractionation Homo sapiens
80 MKI67  
Affinity Capture-MS Homo sapiens
81 C20orf197  
Affinity Capture-MS Homo sapiens
82 RPS24 6229
Proximity Label-MS Homo sapiens
83 RPS7 6201
Co-fractionation Homo sapiens
84 NAP1L5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
85 KRAS 3845
Negative Genetic Homo sapiens
86 HNRNPU 3192
Co-fractionation Homo sapiens
87 RANBP2 5903
Co-fractionation Homo sapiens
88 SYT1 6857
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



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