Gene description for HERC5
Gene name	HECT and RLD domain containing E3 ubiquitin protein ligase 5
Gene symbol	HERC5
Other names/aliases	CEB1 CEBP1
Species	Homo sapiens
Database cross references - HERC5
ExoCarta	ExoCarta_51191
Entrez Gene	51191
HGNC	24368
MIM	608242
UniProt	Q9UII4
HERC5 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells	Unpublished / Not applicable

Gene ontology annotations for HERC5

Molecular Function     ligase activity GO:0016874 IEA     protein binding GO:0005515 IPI     ISG15 transferase activity GO:0042296 IDA     poly(A) RNA binding GO:0044822 IDA     ubiquitin-protein transferase activity GO:0004842 IBA Biological Process     defense response to virus GO:0051607 IEA     protein ubiquitination involved in ubiquitin-dependent protein catabolic process GO:0042787 IBA     negative regulation of type I interferon production GO:0032480 TAS     regulation of cyclin-dependent protein serine/threonine kinase activity GO:0000079 TAS     ISG15-protein conjugation GO:0032020 IDA     regulation of defense response to virus GO:0050688 IDA     cytokine-mediated signaling pathway GO:0019221 TAS     innate immune response GO:0045087 TAS Subcellular Localization     cytosol GO:0005829 TAS     cytoplasm GO:0005737 IBA     perinuclear region of cytoplasm GO:0048471 IEA