Gene description for HNRNPD
Gene name heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
Gene symbol HNRNPD
Other names/aliases AUF1
AUF1A
HNRPD
P37
hnRNPD0
Species Homo sapiens
 Database cross references - HNRNPD
ExoCarta ExoCarta_3184
Vesiclepedia VP_3184
Entrez Gene 3184
HGNC 5036
MIM 601324
UniProt Q14103  
 HNRNPD identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 34887515    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Hepatocellular carcinoma cells 26054723    
Mesenchymal stem cells 36408942    
Neuroblastoma cells 25944692    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Prostate cancer cells 25844599    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
Squamous carcinoma cells 20124223    
Thymus 23844026    
 Gene ontology annotations for HNRNPD
Molecular Function
    minor groove of adenine-thymine-rich DNA binding GO:0003680 IEA
    chromatin binding GO:0003682 IEA
    RNA binding GO:0003723 HDA
    RNA binding GO:0003723 IBA
    RNA binding GO:0003723 IDA
    RNA binding GO:0003723 NAS
    protein binding GO:0005515 IPI
    mRNA 3'-UTR AU-rich region binding GO:0035925 IEA
    telomeric DNA binding GO:0042162 IDA
    histone deacetylase binding GO:0042826 IEA
Biological Process
    liver development GO:0001889 IEA
    regulation of DNA-templated transcription GO:0006355 NAS
    RNA processing GO:0006396 TAS
    RNA catabolic process GO:0006401 TAS
    regulation of gene expression GO:0010468 IBA
    cerebellum development GO:0021549 IEA
    positive regulation of telomere maintenance via telomerase GO:0032212 ISS
    regulation of circadian rhythm GO:0042752 IMP
    positive regulation of translation GO:0045727 IMP
    positive regulation of DNA-templated transcription GO:0045893 NAS
    positive regulation of transcription by RNA polymerase II GO:0045944 ISS
    response to calcium ion GO:0051592 IEA
    response to electrical stimulus GO:0051602 IEA
    3'-UTR-mediated mRNA destabilization GO:0061158 IEA
    CRD-mediated mRNA stabilization GO:0070934 IDA
    cellular response to amino acid stimulus GO:0071230 IEA
    cellular response to estradiol stimulus GO:0071392 IEA
    cellular response to nitric oxide GO:0071732 IEA
    circadian regulation of translation GO:0097167 IMP
    negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:1900152 IDA
    response to rapamycin GO:1901355 IEA
    positive regulation of telomere capping GO:1904355 ISS
    response to sodium phosphate GO:1904383 IEA
    cellular response to putrescine GO:1904586 IEA
    hepatocyte dedifferentiation GO:1990828 IEA
    positive regulation of cytoplasmic translation GO:2000767 IDA
Subcellular Localization
    chromatin GO:0000785 IBA
    nucleus GO:0005634 NAS
    nucleoplasm GO:0005654 IBA
    nucleoplasm GO:0005654 IDA
    nucleoplasm GO:0005654 TAS
    cytosol GO:0005829 IDA
    cytosol GO:0005829 TAS
    postsynaptic density GO:0014069 IEA
    glutamatergic synapse GO:0098978 IEA
    mCRD-mediated mRNA stability complex GO:0106002 IPI
    ribonucleoprotein complex GO:1990904 IDA
 Experiment description of studies that identified HNRNPD in sEVs
1
Experiment ID 489
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 426
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
6
Experiment ID 427
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
7
Experiment ID 497
MISEV standards
Biophysical techniques
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
8
Experiment ID 498
MISEV standards
EM
Biophysical techniques
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
9
Experiment ID 207
MISEV standards
EM
Biophysical techniques
TSG101|HSP70|FLOT1
Enriched markers
VDAC
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 208
MISEV standards
EM
Biophysical techniques
TSG101|HSP70|FLOT1
Enriched markers
VDAC
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
11
Experiment ID 209
MISEV standards
Biophysical techniques
TSG101|HSP70|FLOT1
Enriched markers
VDAC
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
12
Experiment ID 1203
MISEV standards
EM
Biophysical techniques
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
13
Experiment ID 419
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
14
Experiment ID 419
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
15
Experiment ID 420
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
16
Experiment ID 420
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
17
Experiment ID 363
MISEV standards
Biophysical techniques
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
DCLK1
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
18
Experiment ID 364
MISEV standards
Biophysical techniques
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
DCLK1
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
19
Experiment ID 365
MISEV standards
Biophysical techniques
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
DCLK1
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
20
Experiment ID 235
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
21
Experiment ID 488
MISEV standards
EM
Biophysical techniques
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
22
Experiment ID 224
MISEV standards
EM|AFM
Biophysical techniques
Alix|TSG101|CD63|CD81
Enriched markers
GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
23
Experiment ID 211
MISEV standards
EM
Biophysical techniques
TSG101|Alix|EpCAM|TFRC
Enriched markers
cytochrome c|GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
24
Experiment ID 212
MISEV standards
CEM
Biophysical techniques
TSG101|Alix|EpCAM|TFRC
Enriched markers
Cytochrome C|GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
25
Experiment ID 434
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
26
Experiment ID 435
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
27
Experiment ID 275
MISEV standards
EM
Biophysical techniques
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
AIF
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel sensitive
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.12-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry/Flow cytometry/Western blotting
28
Experiment ID 834
MISEV standards
EM
Biophysical techniques
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
29
Experiment ID 835
MISEV standards
EM
Biophysical techniques
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
30
Experiment ID 191
MISEV standards
Biophysical techniques
Alix|CD81|CD9
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
31
Experiment ID 217
MISEV standards
EM
Biophysical techniques
TSG101|CD81|CD9|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for HNRNPD
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 PPP1CB 5500
Affinity Capture-MS Homo sapiens
2 MED17  
Affinity Capture-MS Homo sapiens
3 GMDS 2762
Co-fractionation Homo sapiens
4 ZNF346  
Affinity Capture-MS Homo sapiens
5 GUK1 2987
Two-hybrid Homo sapiens
6 PKM 5315
Co-fractionation Homo sapiens
7 IMMP2L 83943
Two-hybrid Homo sapiens
8 DDX17 10521
Affinity Capture-MS Homo sapiens
9 EBNA-LP  
Affinity Capture-MS
10 BRCA1 672
Affinity Capture-RNA Homo sapiens
Two-hybrid Homo sapiens
11 SMARCE1 6605
Affinity Capture-MS Homo sapiens
12 KIF20A 10112
Affinity Capture-MS Homo sapiens
13 VHL  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
14 LOC100132735  
Protein-RNA Homo sapiens
Affinity Capture-RNA Homo sapiens
15 SIRT5 23408
Affinity Capture-MS Homo sapiens
16 TRN-GTT2-1  
Reconstituted Complex Homo sapiens
17 EIF4E2  
Affinity Capture-MS Homo sapiens
18 ZNF207 7756
Affinity Capture-MS Homo sapiens
19 SEPT9 10801
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
20 WDR76  
Affinity Capture-MS Homo sapiens
21 HIST3H2A 92815
Affinity Capture-MS Homo sapiens
22 PPP1R18 170954
Affinity Capture-MS Homo sapiens
23 ETFA 2108
Affinity Capture-MS Homo sapiens
24 RPS9 6203
Co-fractionation Homo sapiens
25 EXOSC4 54512
Two-hybrid Homo sapiens
26 SFN 2810
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
27 GTSE1 51512
Two-hybrid Homo sapiens
28 MECP2 4204
Affinity Capture-MS Homo sapiens
29 PKN3 29941
Affinity Capture-MS Homo sapiens
30 BTRC 8945
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
31 ARIH2 10425
Affinity Capture-MS Homo sapiens
32 SREK1 140890
Affinity Capture-MS Homo sapiens
33 MTA2 9219
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
34 NTMT1 28989
Two-hybrid Homo sapiens
35 KIF14 9928
Affinity Capture-MS Homo sapiens
36 RBMX 27316
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
37 KLF16  
Affinity Capture-MS Homo sapiens
38 AURKA 6790
Co-fractionation Homo sapiens
39 WNK1 65125
Co-fractionation Homo sapiens
40 SDF2 6388
Two-hybrid Homo sapiens
41 USP11 8237
Affinity Capture-MS Homo sapiens
42 MEPCE 56257
Affinity Capture-MS Homo sapiens
43 HIST1H2AG 8969
Affinity Capture-MS Homo sapiens
44 PPIH 10465
Affinity Capture-MS Homo sapiens
45 SLC25A20 788
Affinity Capture-MS Homo sapiens
46 PABPC1 26986
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
47 CARM1 10498
Affinity Capture-MS Homo sapiens
48 MRPL3  
Affinity Capture-MS Homo sapiens
49 YAP1 10413
Affinity Capture-MS Homo sapiens
50 ACTN4 81
Co-fractionation Homo sapiens
51 OGT 8473
Reconstituted Complex Homo sapiens
52 SYNCRIP 10492
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
53 CD81 975
Two-hybrid Homo sapiens
54 BANF1 8815
Affinity Capture-MS Homo sapiens
55 P4HB 5034
Two-hybrid Homo sapiens
56 ENO1 2023
Affinity Capture-RNA Homo sapiens
57 HECTD1 25831
Affinity Capture-MS Homo sapiens
58 CUL2 8453
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
59 CAPN1 823
Two-hybrid Homo sapiens
60 ACTC1 70
Proximity Label-MS Homo sapiens
61 PICALM 8301
Co-fractionation Homo sapiens
62 VDAC2 7417
Co-fractionation Homo sapiens
63 PAPSS2 9060
Co-fractionation Homo sapiens
64 HIST1H2BH 8345
Affinity Capture-MS Homo sapiens
65 MED15  
Affinity Capture-MS Homo sapiens
66 LRP8 7804
Affinity Capture-MS Homo sapiens
67 SCARNA22  
Affinity Capture-RNA Homo sapiens
68 ANLN 54443
Affinity Capture-MS Homo sapiens
69 HIST1H2BL 8340
Affinity Capture-MS Homo sapiens
70 HIST1H2AD 3013
Affinity Capture-MS Homo sapiens
71 HSPA5 3309
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
72 GTF3C3 9330
Two-hybrid Homo sapiens
73 ARHGAP32  
Affinity Capture-MS Homo sapiens
74 C2orf49 79074
Co-fractionation Homo sapiens
75 HADHB 3032
Co-fractionation Homo sapiens
76 TARBP1 6894
Affinity Capture-MS Homo sapiens
77 DAP3 7818
Affinity Capture-MS Homo sapiens
78 BAG1 573
Affinity Capture-MS Homo sapiens
79 TNFRSF1A 7132
Affinity Capture-MS Homo sapiens
80 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
81 YWHAZ 7534
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
82 PYCR1 5831
Two-hybrid Homo sapiens
83 EPRS 2058
Co-fractionation Homo sapiens
84 FN1 2335
Affinity Capture-MS Homo sapiens
85 HEXA 3073
Affinity Capture-MS Homo sapiens
86 HIST1H1B 3009
Affinity Capture-MS Homo sapiens
87 PCBP1 5093
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
88 MED24 9862
Affinity Capture-MS Homo sapiens
89 RPA3 6119
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
90 UHRF1BP1 54887
Affinity Capture-MS Homo sapiens
91 USP24 23358
Affinity Capture-MS Homo sapiens
92 HSPA1A 3303
Co-fractionation Homo sapiens
93 HSPA4 3308
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
94 HIST1H1A 3024
Affinity Capture-MS Homo sapiens
95 SMARCD2 6603
Affinity Capture-MS Homo sapiens
96 CSDE1 7812
Co-fractionation Homo sapiens
97 CETN2 1069
Affinity Capture-MS Homo sapiens
98 HIST1H2AJ 8331
Affinity Capture-MS Homo sapiens
99 MED14  
Affinity Capture-MS Homo sapiens
100 HIST1H2AC 8334
Affinity Capture-MS Homo sapiens
101 PAIP1 10605
Affinity Capture-Western Homo sapiens
102 TLN2 83660
Affinity Capture-MS Homo sapiens
103 YBX1 4904
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
104 GRB2 2885
Affinity Capture-MS Homo sapiens
105 CDK8 1024
Affinity Capture-MS Homo sapiens
106 HIST1H2BC 8347
Affinity Capture-MS Homo sapiens
107 HIST1H2BN 8341
Affinity Capture-MS Homo sapiens
108 PPOX 5498
Two-hybrid Homo sapiens
109 G3BP2 9908
Affinity Capture-MS Homo sapiens
110 MYH1  
Affinity Capture-MS Homo sapiens
111 TARS 6897
Co-fractionation Homo sapiens
112 SSBP1 6742
Proximity Label-MS Homo sapiens
113 DYNC1H1 1778
Affinity Capture-MS Homo sapiens
114 MED16 10025
Affinity Capture-MS Homo sapiens
115 NCL 4691
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
116 BCL2  
Two-hybrid Homo sapiens
Affinity Capture-RNA Homo sapiens
117 HNRNPL 3191
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
118 EIF4B 1975
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
119 CISD2 493856
Affinity Capture-MS Homo sapiens
120 SNW1 22938
Affinity Capture-MS Homo sapiens
121 ADGRE5 976
Two-hybrid Homo sapiens
122 MRPL55  
Affinity Capture-MS Homo sapiens
123 COG7 91949
Two-hybrid Homo sapiens
124 IFIT2 3433
Affinity Capture-MS Homo sapiens
125 MORC2  
Affinity Capture-MS Homo sapiens
126 HNRNPH1 3187
Affinity Capture-MS Homo sapiens
Affinity Capture-RNA Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
127 DENR 8562
Co-fractionation Homo sapiens
128 H2AFJ 55766
Affinity Capture-MS Homo sapiens
129 HSPA6 3310
Affinity Capture-MS Homo sapiens
130 ZNF286A  
Affinity Capture-MS Homo sapiens
131 USP13  
Affinity Capture-MS Homo sapiens
132 EIF3K 27335
Co-fractionation Homo sapiens
133 GTF2IRD1  
Affinity Capture-MS Homo sapiens
134 RPA2 6118
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
135 ZFR 51663
Affinity Capture-MS Homo sapiens
136 CAND1 55832
Affinity Capture-MS Homo sapiens
137 UAP1 6675
Affinity Capture-MS Homo sapiens
138 SAFB 6294
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
139 PGK1 5230
Co-fractionation Homo sapiens
140 ZMIZ1 57178
Affinity Capture-MS Homo sapiens
141 UCP3  
Protein-RNA Homo sapiens
142 H1FX 8971
Affinity Capture-MS Homo sapiens
143 COPS6 10980
Affinity Capture-MS Homo sapiens
144 TLN1 7094
Affinity Capture-MS Homo sapiens
145 PRC1 9055
Affinity Capture-MS Homo sapiens
146 NPM1 4869
Affinity Capture-MS Homo sapiens
147 KHDRBS1 10657
Affinity Capture-MS Homo sapiens
148 OBSL1 23363
Affinity Capture-MS Homo sapiens
149 GGCT 79017
Co-fractionation Homo sapiens
150 DNAJC7 7266
Co-fractionation Homo sapiens
151 VCAM1 7412
Affinity Capture-MS Homo sapiens
152 TOMM40 10452
Co-fractionation Homo sapiens
153 CUL1 8454
Affinity Capture-MS Homo sapiens
154 HSD17B4 3295
Affinity Capture-MS Homo sapiens
155 MED4 29079
Affinity Capture-MS Homo sapiens
156 IPO11 51194
Co-fractionation Homo sapiens
157 HIST2H2AB 317772
Affinity Capture-MS Homo sapiens
158 HNRNPA0 10949
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
159 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
160 DDX21 9188
Affinity Capture-MS Homo sapiens
161 KLHDC2  
Affinity Capture-MS Homo sapiens
162 NHS 4810
Affinity Capture-MS Homo sapiens
163 BAG6 7917
Affinity Capture-MS Homo sapiens
164 VRK1 7443
Affinity Capture-MS Homo sapiens
165 NELFE 7936
Affinity Capture-MS Homo sapiens
166 INTS7  
Affinity Capture-MS Homo sapiens
167 PPM1A 5494
Affinity Capture-MS Homo sapiens
168 GAPDH 2597
Co-fractionation Homo sapiens
169 UQCRC1 7384
Two-hybrid Homo sapiens
170 RIN3  
Affinity Capture-MS Homo sapiens
171 RPLP0 6175
Co-fractionation Homo sapiens
172 CYLD  
Affinity Capture-MS Homo sapiens
173 PTGR2 145482
Affinity Capture-MS Homo sapiens
174 ZCCHC8 55596
Affinity Capture-MS Homo sapiens
175 ESPL1  
Affinity Capture-MS Homo sapiens
176 HNRNPD 3184
FRET Homo sapiens
FRET Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
FRET Homo sapiens
FRET Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
177 KHSRP 8570
Co-fractionation Homo sapiens
178 SMARCAD1  
Affinity Capture-MS Homo sapiens
179 CCNC  
Affinity Capture-MS Homo sapiens
180 SMEK2  
Affinity Capture-MS Homo sapiens
181 EIF6 3692
Affinity Capture-MS Homo sapiens
182 RC3H2  
Affinity Capture-MS Homo sapiens
183 RASIP1  
Affinity Capture-MS Homo sapiens
184 YLPM1 56252
Affinity Capture-MS Homo sapiens
185 ABCC10  
Two-hybrid Homo sapiens
186 FUS 2521
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
187 HNRNPF 3185
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
188 Cep152  
Affinity Capture-MS Mus musculus
189 CDK2 1017
Affinity Capture-MS Homo sapiens
190 WDR24  
Affinity Capture-MS Homo sapiens
191 HIST1H2AH 85235
Affinity Capture-MS Homo sapiens
192 MYC  
Affinity Capture-MS Homo sapiens
Protein-RNA Homo sapiens
Protein-RNA Homo sapiens
Affinity Capture-RNA Homo sapiens
193 ERG  
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
194 SLC3A2 6520
Two-hybrid Homo sapiens
195 BLMH 642
Affinity Capture-MS Homo sapiens
196 HNRNPAB 3182
Cross-Linking-MS (XL-MS) Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
197 CUL7 9820
Affinity Capture-MS Homo sapiens
198 DDRGK1 65992
Affinity Capture-MS Homo sapiens
199 FAM120A 23196
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
200 FBXL15  
Two-hybrid Homo sapiens
201 TSEN34 79042
Two-hybrid Homo sapiens
202 HNRNPH2 3188
Affinity Capture-MS Homo sapiens
203 PARP1 142
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
204 ILF3 3609
Affinity Capture-MS Homo sapiens
205 PDCL 5082
Affinity Capture-MS Homo sapiens
206 SF3B4 10262
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
207 EZR 7430
Co-fractionation Homo sapiens
208 RPS12 6206
Co-fractionation Homo sapiens
209 PTBP1 5725
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
210 PTBP2  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
211 MAP2K1 5604
Two-hybrid Homo sapiens
212 HNRNPK 3190
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
213 ESR1  
Reconstituted Complex Homo sapiens
214 KHDRBS2  
Affinity Capture-MS Homo sapiens
215 IL7R  
Protein-RNA Homo sapiens
216 DKC1 1736
Affinity Capture-MS Homo sapiens
217 C1QBP 708
Two-hybrid Homo sapiens
218 ASB2  
Affinity Capture-MS Homo sapiens
219 PRMT1 3276
Affinity Capture-MS Homo sapiens
220 PDRG1  
Affinity Capture-MS Homo sapiens
221 TOMM5  
Co-fractionation Homo sapiens
222 CUL4A 8451
Affinity Capture-MS Homo sapiens
223 HBZ  
Two-hybrid Homo sapiens
224 RALY 22913
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
225 GCFC2  
Affinity Capture-MS Homo sapiens
226 RPSA 3921
Two-hybrid Homo sapiens
227 HNRNPC 3183
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
228 MTX1 4580
Co-fractionation Homo sapiens
229 CD4 920
Affinity Capture-MS Homo sapiens
230 SSB 6741
Affinity Capture-MS Homo sapiens
231 HNRNPCL1 343069
Affinity Capture-MS Homo sapiens
232 FUBP3 8939
Affinity Capture-MS Homo sapiens
233 HNRNPR 10236
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
234 RET 5979
Affinity Capture-MS Homo sapiens
235 HIST2H2AA3 8337
Affinity Capture-MS Homo sapiens
236 CAPZB 832
Affinity Capture-MS Homo sapiens
237 SBF2 81846
Affinity Capture-MS Homo sapiens
238 MYEF2 50804
Affinity Capture-MS Homo sapiens
239 HEATR3 55027
Affinity Capture-MS Homo sapiens
240 MCM2 4171
Affinity Capture-MS Homo sapiens
241 CHMP5 51510
Affinity Capture-MS Homo sapiens
242 MCTS1 28985
Cross-Linking-MS (XL-MS) Homo sapiens
243 EWSR1 2130
Affinity Capture-MS Homo sapiens
244 HIST2H2AC 8338
Affinity Capture-MS Homo sapiens
245 ITGA4 3676
Affinity Capture-MS Homo sapiens
246 ATRX 546
Cross-Linking-MS (XL-MS) Homo sapiens
247 ATG16L1 55054
Affinity Capture-MS Homo sapiens
248 GOLGA4  
Affinity Capture-MS Homo sapiens
249 GPN1  
Affinity Capture-MS Homo sapiens
250 TFCP2 7024
Affinity Capture-MS Homo sapiens
251 MRPL4 51073
Affinity Capture-MS Homo sapiens
252 GPRIN1 114787
Affinity Capture-MS Homo sapiens
253 RBM8A 9939
Affinity Capture-MS Homo sapiens
254 HSPA8 3312
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
255 FOXP1 27086
Protein-RNA Homo sapiens
256 AGO2 27161
Affinity Capture-MS Homo sapiens
257 PINX1  
Affinity Capture-MS Homo sapiens
258 CUL4B 8450
Affinity Capture-MS Homo sapiens
259 PARK2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
260 PTGS2 5743
Affinity Capture-RNA Homo sapiens
261 BTF3L4 91408
Cross-Linking-MS (XL-MS) Homo sapiens
262 BET1L 51272
Two-hybrid Homo sapiens
263 NTRK1 4914
Affinity Capture-MS Homo sapiens
264 OSBPL2 9885
Affinity Capture-MS Homo sapiens
265 U2AF2 11338
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
266 EVPL 2125
Cross-Linking-MS (XL-MS) Homo sapiens
267 ACTB 60
Two-hybrid Homo sapiens
268 CTSB 1508
Two-hybrid Homo sapiens
269 DHX9 1660
Affinity Capture-MS Homo sapiens
270 POLR2B 5431
Affinity Capture-MS Homo sapiens
271 TMEM261  
Two-hybrid Homo sapiens
272 HNRNPA3 220988
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
273 HDAC5 10014
Affinity Capture-MS Homo sapiens
274 RMDN3 55177
Co-fractionation Homo sapiens
275 PCBP2 5094
Two-hybrid Homo sapiens
276 LARP1 23367
Affinity Capture-MS Homo sapiens
277 HNRNPDL 9987
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
278 DPF2  
Affinity Capture-MS Homo sapiens
279 METTL14  
Affinity Capture-MS Homo sapiens
280 MSH2 4436
Co-fractionation Homo sapiens
281 ECT2 1894
Affinity Capture-MS Homo sapiens
282 SNAPC4  
Two-hybrid Homo sapiens
283 EEF2 1938
Two-hybrid Homo sapiens
284 HIST1H1E 3008
Affinity Capture-MS Homo sapiens
285 NR3C1 2908
Affinity Capture-MS Homo sapiens
286 DTX2 113878
Proximity Label-MS Homo sapiens
287 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
288 DHX30 22907
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
289 ARRB2 409
Affinity Capture-MS Homo sapiens
290 POLR2A 5430
Affinity Capture-MS Homo sapiens
291 COG2 22796
Affinity Capture-MS Homo sapiens
292 MEOX2  
Two-hybrid Homo sapiens
293 SPOP  
Affinity Capture-MS Homo sapiens
294 HIST1H1C 3006
Affinity Capture-MS Homo sapiens
295 MTOR 2475
Affinity Capture-MS Homo sapiens
296 TP63  
Affinity Capture-MS Homo sapiens
297 TOP1 7150
Affinity Capture-MS Homo sapiens
298 ITGB4 3691
Affinity Capture-MS Homo sapiens
299 MATR3 9782
Affinity Capture-MS Homo sapiens
300 GPBP1  
Affinity Capture-MS Homo sapiens
301 BEND3  
Cross-Linking-MS (XL-MS) Homo sapiens
302 ZC3HAV1 56829
Affinity Capture-MS Homo sapiens
303 KIAA0368 23392
Affinity Capture-MS Homo sapiens
304 HSPA9 3313
Co-fractionation Homo sapiens
305 OBSCN 84033
Affinity Capture-MS Homo sapiens
306 NEDD4L 23327
Protein-RNA Homo sapiens
Affinity Capture-RNA Homo sapiens
307 XRCC5 7520
Affinity Capture-MS Homo sapiens
308 IMMT 10989
Two-hybrid Homo sapiens
309 PRMT3 10196
Affinity Capture-MS Homo sapiens
310 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
311 FBXW11  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
312 RPS3 6188
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
313 HIST1H2BK 85236
Affinity Capture-MS Homo sapiens
314 CUTA 51596
Two-hybrid Homo sapiens
315 AGO1  
Affinity Capture-MS Homo sapiens
316 SLC27A5 10998
Two-hybrid Homo sapiens
317 KAT2B  
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
318 RPA1 6117
Affinity Capture-MS Homo sapiens
319 SNRPA 6626
Affinity Capture-MS Homo sapiens
320 HNRNPM 4670
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
321 TUBB3 10381
Affinity Capture-MS Homo sapiens
322 G3BP1 10146
Affinity Capture-MS Homo sapiens
323 HSPB1 3315
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
FRET Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
FRET Homo sapiens
Affinity Capture-Western Homo sapiens
324 Shoc2  
Affinity Capture-MS Mus musculus
325 LOC102724334 102724334
Affinity Capture-MS Homo sapiens
326 S100A9 6280
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
327 ACSL4 2182
Affinity Capture-MS Homo sapiens
328 UFL1 23376
Affinity Capture-MS Homo sapiens
329 MALAT1 378938
Affinity Capture-RNA Homo sapiens
330 MED12  
Affinity Capture-MS Homo sapiens
331 HNRNPH3 3189
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
332 FLNA 2316
Two-hybrid Homo sapiens
333 METTL3  
Affinity Capture-MS Homo sapiens
334 SERBP1 26135
Affinity Capture-MS Homo sapiens
335 RC3H1 149041
Affinity Capture-MS Homo sapiens
336 SSRP1 6749
Affinity Capture-MS Homo sapiens
337 Kif1c  
Affinity Capture-MS Mus musculus
338 SP100 6672
Cross-Linking-MS (XL-MS) Homo sapiens
339 HIST1H2AE 3012
Affinity Capture-MS Homo sapiens
340 IGF2BP2 10644
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
341 DYSF 8291
Affinity Capture-MS Homo sapiens
342 EP300 2033
Affinity Capture-MS Homo sapiens
343 HNRNPA2B1 3181
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
344 UBE2H 7328
Affinity Capture-MS Homo sapiens
345 IGF2BP1 10642
Affinity Capture-MS Homo sapiens
346 COIL  
Proximity Label-MS Homo sapiens
347 TNPO1 3842
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
348 HIST1H1D 3007
Affinity Capture-MS Homo sapiens
349 TROVE2 6738
Co-fractionation Homo sapiens
350 GBA 2629
Affinity Capture-MS Homo sapiens
351 TOMM22 56993
Co-fractionation Homo sapiens
352 UBE2G2  
Co-fractionation Homo sapiens
353 TOP2A 7153
Reconstituted Complex Homo sapiens
354 PRDX3 10935
Two-hybrid Homo sapiens
355 COPS5 10987
Affinity Capture-MS Homo sapiens
356 FBXW7  
Affinity Capture-Western Homo sapiens
357 AGO3  
Affinity Capture-MS Homo sapiens
358 MRPL12 6182
Co-fractionation Homo sapiens
359 SNRPC 6631
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
360 IFIT3 3437
Affinity Capture-MS Homo sapiens
361 DDX51  
Affinity Capture-MS Homo sapiens
362 SLC30A5 64924
Co-fractionation Homo sapiens
363 DGCR2 9993
Two-hybrid Homo sapiens
364 NME2 4831
Co-fractionation Homo sapiens
365 MYCN  
Affinity Capture-MS Homo sapiens
366 SMARCB1 6598
Affinity Capture-MS Homo sapiens
367 ERI1  
Co-fractionation Homo sapiens
368 ALAS2  
Cross-Linking-MS (XL-MS) Homo sapiens
369 CINP  
Two-hybrid Homo sapiens
370 TNF  
Affinity Capture-RNA Homo sapiens
Protein-RNA Homo sapiens
371 MRPS30 10884
Affinity Capture-MS Homo sapiens
372 PPP1CA 5499
Affinity Capture-MS Homo sapiens
373 ING4  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
374 NAA50 80218
Co-fractionation Homo sapiens
375 PLXNB1 5364
Affinity Capture-MS Homo sapiens
376 STAU1 6780
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
377 SRSF6 6431
Affinity Capture-MS Homo sapiens
378 UBE2I 7329
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
379 VCP 7415
Affinity Capture-MS Homo sapiens
380 IFI16 3428
Affinity Capture-MS Homo sapiens
381 CHEK1  
Co-fractionation Homo sapiens
382 AHNAK 79026
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
383 DCTN1 1639
Cross-Linking-MS (XL-MS) Homo sapiens
384 DICER1  
Affinity Capture-MS Homo sapiens
385 DDX1 1653
Co-fractionation Homo sapiens
386 DNM2 1785
Affinity Capture-MS Homo sapiens
387 EED  
Affinity Capture-MS Homo sapiens
388 CEBPA  
Protein-peptide Homo sapiens
389 SMARCC2 6601
Affinity Capture-MS Homo sapiens
390 HIST1H2AA 221613
Affinity Capture-MS Homo sapiens
391 SFPQ 6421
Co-fractionation Homo sapiens
392 MPP1 4354
Two-hybrid Homo sapiens
393 TOMM34 10953
Co-fractionation Homo sapiens
394 FANCD2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
395 CDK9 1025
Affinity Capture-MS Homo sapiens
396 TAX1BP1 8887
Affinity Capture-MS Homo sapiens
397 VEGFA 7422
Protein-RNA Homo sapiens
Affinity Capture-RNA Homo sapiens
Affinity Capture-RNA Homo sapiens
Protein-RNA Homo sapiens
398 EIF4G1 1981
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
399 SNRPB 6628
Affinity Capture-MS Homo sapiens
400 ERCC8  
Affinity Capture-MS Homo sapiens
401 PEX10  
Two-hybrid Homo sapiens
402 RPL7 6129
Cross-Linking-MS (XL-MS) Homo sapiens
403 NXF1 10482
Affinity Capture-RNA Homo sapiens
404 MRPL1  
Affinity Capture-MS Homo sapiens
405 MAPK6  
Two-hybrid Homo sapiens
406 C2CD5 9847
Affinity Capture-MS Homo sapiens
407 DCUN1D1 54165
Affinity Capture-MS Homo sapiens
408 FOS 2353
Reconstituted Complex Homo sapiens
Protein-RNA Homo sapiens
409 MAP3K4 4216
Affinity Capture-MS Homo sapiens
410 SHISA5 51246
Two-hybrid Homo sapiens
411 FNDC3A 22862
Affinity Capture-MS Homo sapiens
412 SRSF10 10772
Affinity Capture-MS Homo sapiens
413 B3GAT3 26229
Two-hybrid Homo sapiens
414 GNB2L1 10399
Affinity Capture-MS Homo sapiens
415 MDM2  
Affinity Capture-RNA Homo sapiens
416 H2AFX 3014
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
417 PDLIM7 9260
Two-hybrid Homo sapiens
418 VDAC3 7419
Co-fractionation Homo sapiens
419 NRP1 8829
Affinity Capture-MS Homo sapiens
420 PLEKHA6 22874
Cross-Linking-MS (XL-MS) Homo sapiens
421 HSPB2  
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
FRET Homo sapiens
422 PAFAH1B3 5050
Co-fractionation Homo sapiens
423 CPSF6 11052
Affinity Capture-MS Homo sapiens
424 PNPLA8 50640
Affinity Capture-MS Homo sapiens
425 SMARCC1 6599
Affinity Capture-MS Homo sapiens
426 SAP18 10284
Affinity Capture-MS Homo sapiens
427 CUL5 8065
Affinity Capture-MS Homo sapiens
428 ABCA7 10347
Affinity Capture-MS Homo sapiens
429 SMURF1 57154
Affinity Capture-MS Homo sapiens
430 ELAVL1 1994
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
431 COL18A1 80781
Two-hybrid Homo sapiens
432 HDAC1 3065
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
433 HIST1H2BD 3017
Affinity Capture-MS Homo sapiens
434 LSM5  
Two-hybrid Homo sapiens
435 ARF4 378
Two-hybrid Homo sapiens
436 RPS28 6234
Co-fractionation Homo sapiens
437 RBM4 5936
Affinity Capture-MS Homo sapiens
438 MOV10 4343
Affinity Capture-RNA Homo sapiens
439 PYGB 5834
Co-fractionation Homo sapiens
440 TRIM31  
Affinity Capture-MS Homo sapiens
441 PINK1  
Affinity Capture-MS Homo sapiens
442 GRSF1 2926
Proximity Label-MS Homo sapiens
443 XRCC6 2547
Affinity Capture-MS Homo sapiens
444 HIRA  
Two-hybrid Homo sapiens
445 HNRNPU 3192
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
446 C9orf72  
Affinity Capture-MS Homo sapiens
447 METTL17  
Proximity Label-MS Homo sapiens
448 IVNS1ABP  
Affinity Capture-MS Homo sapiens
449 STRBP 55342
Affinity Capture-MS Homo sapiens
450 NEDD8 4738
Affinity Capture-MS Homo sapiens
451 HTR1A  
Affinity Capture-MS Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here