Gene description for HTATSF1
Gene name HIV-1 Tat specific factor 1
Gene symbol HTATSF1
Other names/aliases TAT-SF1
TATSF1
dJ196E23.2
Species Homo sapiens
 Database cross references - HTATSF1
ExoCarta ExoCarta_27336
Entrez Gene 27336
HGNC 5276
MIM 300346
UniProt O43719  
 HTATSF1 identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
 Gene ontology annotations for HTATSF1
Molecular Function
    poly(A) RNA binding GO:0044822 IDA
    nucleotide binding GO:0000166 IEA
Biological Process
    regulation of DNA-templated transcription, elongation GO:0032784 TAS
    regulation of transcription from RNA polymerase II promoter GO:0006357 TAS
    viral genome replication GO:0019079 TAS
    transcription, DNA-templated GO:0006351 IEA
Subcellular Localization
    nucleus GO:0005634 TAS
    nucleoplasm GO:0005654 IDA
 Experiment description of studies that identified HTATSF1 in exosomes
1
Experiment ID 211
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
EpCAM|TFRC
EV Membrane markers
cytochrome c|GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 212
ISEV standards
CEM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
EpCAM|TFRC
EV Membrane markers
Cytochrome C|GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for HTATSF1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SNRPB 6628
Affinity Capture-MS Homo sapiens
2 FEZ1  
Two-hybrid Homo sapiens
3 NCL 4691
Invivo Homo sapiens
Invitro Homo sapiens
4 SF3A2 8175
Affinity Capture-Western Homo sapiens
5 GTF2F2  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
6 CDK9 1025
Invitro Homo sapiens
Invivo Homo sapiens
7 SUPT5H 6829
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
8 CCNT1  
Reconstituted Complex Homo sapiens
9 POLR2A 5430
Affinity Capture-Western Homo sapiens
View the network image/svg+xml
 Pathways in which HTATSF1 is involved
No pathways found





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