Experiment description of studies that identified HTT in exosomes

1 Experiment ID 217 ISEV standards ✔ EM EV Biophysical techniques ✔ TSG101 EV Cytosolic markers ✔ CD81|CD9|CD63 EV Membrane markers ✘ EV Negative markers ✔ NTA EV Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 23844026     Organism Homo sapiens Experiment description Characterization of human thymic exosomes. Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O. Journal name PLoS One Publication year 2013 Sample Thymus Sample name Normal-Thymus Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry

Protein-protein interactions for HTT

Protein Interactor ExoCarta ID Identification method PubMed Species 1 HAP1   Invivo Homo sapiens Invivo Homo sapiens Invitro Homo sapiens Invitro Homo sapiens Two-hybrid Homo sapiens Two-hybrid Homo sapiens Two-hybrid Homo sapiens Two-hybrid Homo sapiens Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens 2 RASA1 5921 Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens 3 CXorf27   Two-hybrid Homo sapiens 4 GRB2 2885 Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens 5 HYPB   Reconstituted Complex Homo sapiens Two-hybrid Homo sapiens 6 Sin3a   Reconstituted Complex Mus musculus 7 SP1   Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens 8 F8A1   Affinity Capture-Western Homo sapiens 9 TCERG1   Reconstituted Complex Homo sapiens 10 EGFR 1956 Affinity Capture-Western Homo sapiens 11 ZK1127.9   Two-hybrid 6239 12 HYPE   Two-hybrid Homo sapiens 13 CTBP1 1487 Invivo Homo sapiens 14 PRPF40A 55660 Reconstituted Complex Homo sapiens Two-hybrid Homo sapiens 15 HYPC   Reconstituted Complex Homo sapiens Two-hybrid Homo sapiens 16 OPTN 10133 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 17 CREBBP   Co-fractionation Homo sapiens 18 SH3GL3   Two-hybrid Homo sapiens Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens 19 Crebbp   Reconstituted Complex Mus musculus 20 NCOR1   Two-hybrid Homo sapiens 21 GAPDH 2597 Invitro Homo sapiens 22 HYPK   Two-hybrid Homo sapiens Two-hybrid Homo sapiens 23 SH3GLB1 51100 Reconstituted Complex Homo sapiens 24 UBE2K 3093 Invitro Homo sapiens Two-hybrid Homo sapiens Two-hybrid Homo sapiens 25 TP53   Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens 26 AP2A2 161 Two-hybrid Homo sapiens 27 ESRRBL1   Invivo Homo sapiens 28 TRIP10 9322 Two-hybrid Homo sapiens Reconstituted Complex Homo sapiens 29 HIP1 3092 Two-hybrid Homo sapiens Two-hybrid Homo sapiens Reconstituted Complex Homo sapiens 30 NEUROD1   Affinity Capture-Western Homo sapiens 31 MAGEA3   Two-hybrid Homo sapiens 32 Ncor1   Reconstituted Complex Rattus norvegicus 33 MAP3K10   Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens 34 PACSIN1   Two-hybrid Homo sapiens Reconstituted Complex Homo sapiens 35 TPH1   Invitro Homo sapiens 36 ZDHHC17   Reconstituted Complex Homo sapiens Two-hybrid Homo sapiens Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens View the network

Pathways in which HTT is involved

No pathways found