Gene description for GTF2B
Gene name	general transcription factor IIB
Gene symbol	GTF2B
Other names/aliases	TF2B TFIIB
Species	Homo sapiens
Database cross references - GTF2B
ExoCarta	ExoCarta_2959
Vesiclepedia	VP_2959
Entrez Gene	2959
HGNC	4648
MIM	189963
UniProt	Q00403
GTF2B identified in sEVs derived from the following tissue/cell type
Thymus	23844026

Gene ontology annotations for GTF2B

Molecular Function     RNA polymerase II core promoter sequence-specific DNA binding GO:0000979 IBA     RNA polymerase II core promoter sequence-specific DNA binding GO:0000979 IDA     RNA polymerase II complex binding GO:0000993 IDA     protein binding GO:0005515 IPI     zinc ion binding GO:0008270 IDA     RNA polymerase II general transcription initiation factor activity GO:0016251 IBA     RNA polymerase II general transcription initiation factor activity GO:0016251 IDA     acetyltransferase activity GO:0016407 IBA     acetyltransferase activity GO:0016407 IDA     TBP-class protein binding GO:0017025 IBA     TBP-class protein binding GO:0017025 IPI     histone H3K56 acetyltransferase activity GO:0032931 IEA     histone H3K14 acetyltransferase activity GO:0036408 IEA     histone H3K9 acetyltransferase activity GO:0043992 IEA     histone H3K18 acetyltransferase activity GO:0043993 IEA     histone H3K23 acetyltransferase activity GO:0043994 IEA     histone H4K5 acetyltransferase activity GO:0043995 IEA     histone H4K8 acetyltransferase activity GO:0043996 IEA     histone H4K12 acetyltransferase activity GO:0043997 IEA     histone H2AK5 acetyltransferase activity GO:0043999 IEA     histone H2AK9 acetyltransferase activity GO:0044012 IEA     histone H2BK5 acetyltransferase activity GO:0044014 IEA     histone H2BK12 acetyltransferase activity GO:0044015 IEA     histone H3K4 acetyltransferase activity GO:0044016 IEA     histone H3K27 acetyltransferase activity GO:0044017 IEA     histone H3K36 acetyltransferase activity GO:0044018 IEA     nuclear thyroid hormone receptor binding GO:0046966 IPI     histone H4K16 acetyltransferase activity GO:0046972 IEA     DNA-binding transcription factor binding GO:0140297 IPI     histone H3K122 acetyltransferase activity GO:0140908 IEA     promoter-specific chromatin binding GO:1990841 IDA Biological Process     transcriptional start site selection at RNA polymerase II promoter GO:0001174 IBA     transcriptional start site selection at RNA polymerase II promoter GO:0001174 IMP     chromatin remodeling GO:0006338 IEA     DNA-templated transcription initiation GO:0006352 IBA     transcription by RNA polymerase II GO:0006366 IDA     transcription by RNA polymerase II GO:0006366 IMP     transcription initiation at RNA polymerase II promoter GO:0006367 IDA     transcription initiation at RNA polymerase II promoter GO:0006367 IMP     protein acetylation GO:0006473 IDA     viral transcription GO:0019083 IDA     viral transcription GO:0019083 IMP     RNA polymerase II preinitiation complex assembly GO:0051123 IBA     RNA polymerase II preinitiation complex assembly GO:0051123 IDA     RNA polymerase II preinitiation complex assembly GO:0051123 IMP     meiotic sister chromatid cohesion GO:0051177 IEA     spindle assembly GO:0051225 IEA     positive regulation of core promoter binding GO:1904798 IDA     RNA polymerase II core complex assembly GO:1990114 IBA     RNA polymerase II core complex assembly GO:1990114 IMP Subcellular Localization     kinetochore GO:0000776 IEA     nucleus GO:0005634 IBA     nucleus GO:0005634 IDA     nucleoplasm GO:0005654 IDA     nucleoplasm GO:0005654 TAS     transcription factor TFIID complex GO:0005669 IDA     chromosome GO:0005694 IDA     nuclear body GO:0016604 IDA     cell division site GO:0032153 IEA     protein-DNA complex GO:0032993 IDA     germinal vesicle GO:0042585 IEA     RNA polymerase II transcription regulator complex GO:0090575 IDA     RNA polymerase II transcription regulator complex GO:0090575 IMP     transcription preinitiation complex GO:0097550 IBA