Gene description for SF3A1
Gene name splicing factor 3a, subunit 1, 120kDa
Gene symbol SF3A1
Other names/aliases PRP21
PRPF21
SAP114
SF3A120
Species Homo sapiens
 Database cross references - SF3A1
ExoCarta ExoCarta_10291
Vesiclepedia VP_10291
Entrez Gene 10291
HGNC 10765
MIM 605595
UniProt Q15459  
 SF3A1 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Hepatocytes 26054723    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
T lymphocytes 34108659    
Thymus 23844026    
 Gene ontology annotations for SF3A1
Molecular Function
    RNA binding GO:0003723 HDA
    RNA binding GO:0003723 IBA
    RNA binding GO:0003723 IDA
    protein binding GO:0005515 IPI
Biological Process
    mRNA 3'-splice site recognition GO:0000389 TAS
    mRNA splicing, via spliceosome GO:0000398 IC
    mRNA splicing, via spliceosome GO:0000398 IDA
    mRNA splicing, via spliceosome GO:0000398 NAS
    mRNA processing GO:0006397 IMP
    mRNA cis splicing, via spliceosome GO:0045292 IEA
    U2-type prespliceosome assembly GO:1903241 IDA
    U2-type prespliceosome assembly GO:1903241 NAS
Subcellular Localization
    nucleus GO:0005634 IDA
    nucleus GO:0005634 NAS
    nucleoplasm GO:0005654 IDA
    nucleoplasm GO:0005654 TAS
    spliceosomal complex GO:0005681 IDA
    spliceosomal complex GO:0005681 NAS
    U2-type spliceosomal complex GO:0005684 IDA
    U2-type spliceosomal complex GO:0005684 IPI
    U2 snRNP GO:0005686 IBA
    U2 snRNP GO:0005686 IDA
    U2 snRNP GO:0005686 NAS
    nuclear speck GO:0016607 IDA
    U2-type prespliceosome GO:0071004 IBA
    U2-type prespliceosome GO:0071004 IDA
    U2-type precatalytic spliceosome GO:0071005 IDA
    catalytic step 2 spliceosome GO:0071013 IBA
    catalytic step 2 spliceosome GO:0071013 IDA
 Experiment description of studies that identified SF3A1 in sEVs
1
Experiment ID 489
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
10
Experiment ID 498
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
11
Experiment ID 407
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
12
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
13
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
14
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
15
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
16
Experiment ID 405
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
17
Experiment ID 237
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
18
Experiment ID 417
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
19
Experiment ID 411
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
20
Experiment ID 418
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
21
Experiment ID 418
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
22
Experiment ID 413
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
23
Experiment ID 211
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
24
Experiment ID 212
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
25
Experiment ID 406
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
26
Experiment ID 415
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
27
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
28
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
29
Experiment ID 408
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
30
Experiment ID 409
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
31
Experiment ID 416
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
32
Experiment ID 410
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
33
Experiment ID 217
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SF3A1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UBE2H 7328
Affinity Capture-MS Homo sapiens
2 PSMA6 5687
Co-fractionation Homo sapiens
3 NUPL2 11097
Affinity Capture-MS Homo sapiens
4 MAP1LC3C  
Affinity Capture-MS Homo sapiens
5 MCM7 4176
Co-fractionation Homo sapiens
6 RALYL 138046
Affinity Capture-MS Homo sapiens
7 HNRNPC 3183
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
8 ZC3H14  
Affinity Capture-MS Homo sapiens
9 SON 6651
Affinity Capture-MS Homo sapiens
10 SRRM1 10250
Affinity Capture-MS Homo sapiens
11 RALY 22913
Affinity Capture-MS Homo sapiens
12 SNRPG 6637
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 SLFN11 91607
Proximity Label-MS Homo sapiens
14 SNRPE 6635
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
15 COIL  
Affinity Capture-MS Homo sapiens
16 FGB 2244
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 HDAC1 3065
Co-fractionation Homo sapiens
18 RBM22 55696
Affinity Capture-MS Homo sapiens
19 CALML3 810
Affinity Capture-MS Homo sapiens
20 PRPF8 10594
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
21 MSH2 4436
Cross-Linking-MS (XL-MS) Homo sapiens
22 PPIE 10450
Affinity Capture-MS Homo sapiens
23 PUF60 22827
Affinity Capture-MS Homo sapiens
24 RPA2 6118
Affinity Capture-MS Homo sapiens
25 HNRNPDL 9987
Affinity Capture-MS Homo sapiens
26 DDX17 10521
Co-fractionation Homo sapiens
27 ACTC1 70
Proximity Label-MS Homo sapiens
28 SF3B1 23451
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
29 HNRNPL 3191
Affinity Capture-MS Homo sapiens
30 GTF2F1 2962
Co-fractionation Homo sapiens
31 CTNNBL1 56259
Affinity Capture-MS Homo sapiens
32 RPL35A 6165
Affinity Capture-MS Homo sapiens
33 LSM4 25804
Affinity Capture-MS Homo sapiens
34 CSNK2A1 1457
Biochemical Activity Homo sapiens
35 PRPF3  
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
36 N4BP2L2 10443
Affinity Capture-MS Homo sapiens
37 CAND1 55832
Affinity Capture-MS Homo sapiens
38 HNRNPR 10236
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
39 AQR 9716
Affinity Capture-MS Homo sapiens
40 APBB1  
Reconstituted Complex Homo sapiens
41 ZBTB1  
Affinity Capture-MS Homo sapiens
42 SNRPF 6636
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
43 ARHGEF16 27237
Affinity Capture-MS Homo sapiens
44 SF3B5 83443
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
45 SFPQ 6421
Co-fractionation Homo sapiens
46 GSK3A 2931
Affinity Capture-MS Homo sapiens
47 TCEA1 6917
Affinity Capture-MS Homo sapiens
48 KIAA1429 25962
Affinity Capture-MS Homo sapiens
49 SRP54 6729
Co-fractionation Homo sapiens
50 DDX23 9416
Affinity Capture-MS Homo sapiens
51 PARK2  
Affinity Capture-MS Homo sapiens
52 PLEKHG4  
Affinity Capture-MS Homo sapiens
53 NCOR1  
Co-purification Homo sapiens
Co-fractionation Homo sapiens
54 NCBP1 4686
Affinity Capture-MS Homo sapiens
55 USP39 10713
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
56 CRNKL1 51340
Affinity Capture-MS Homo sapiens
57 SKIV2L2 23517
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
58 GTF2E2  
Affinity Capture-MS Homo sapiens
59 PPIL1 51645
Affinity Capture-MS Homo sapiens
60 MCM2 4171
Affinity Capture-MS Homo sapiens
61 ISY1 57461
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
62 SHMT2 6472
Affinity Capture-MS Homo sapiens
63 RAB3IP  
Affinity Capture-MS Homo sapiens
64 TRMT112 51504
Co-fractionation Homo sapiens
65 GEMIN5 25929
Affinity Capture-MS Homo sapiens
66 HNRNPA1 3178
Co-fractionation Homo sapiens
67 POLR3G  
Affinity Capture-MS Homo sapiens
68 PRC1 9055
Affinity Capture-MS Homo sapiens
69 BRCC3 79184
Co-fractionation Homo sapiens
70 MDC1  
Affinity Capture-MS Homo sapiens
71 SNRPC 6631
Affinity Capture-MS Homo sapiens
72 SMU1 55234
Affinity Capture-MS Homo sapiens
73 TRAP1 10131
Affinity Capture-MS Homo sapiens
74 CCAR1 55749
Affinity Capture-MS Homo sapiens
75 OBSL1 23363
Affinity Capture-MS Homo sapiens
76 PQBP1  
Affinity Capture-MS Homo sapiens
77 MCM6 4175
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
78 SF3A2 8175
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
79 SAP18 10284
Affinity Capture-MS Homo sapiens
80 ABCE1 6059
Affinity Capture-MS Homo sapiens
81 C17orf85  
Affinity Capture-MS Homo sapiens
82 ZNF326 284695
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
83 FANCD2  
Affinity Capture-MS Homo sapiens
84 HNRNPA0 10949
Affinity Capture-MS Homo sapiens
85 EED  
Affinity Capture-MS Homo sapiens
86 SLX4  
Affinity Capture-MS Homo sapiens
87 C11orf57  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
88 SSBP1 6742
Co-fractionation Homo sapiens
89 MECP2 4204
Affinity Capture-MS Homo sapiens
90 PABPN1 8106
Affinity Capture-MS Homo sapiens
91 MYCN  
Affinity Capture-MS Homo sapiens
92 HSPA2 3306
Affinity Capture-MS Homo sapiens
93 ZMAT2  
Affinity Capture-MS Homo sapiens
94 SERPINB5 5268
Affinity Capture-MS Homo sapiens
95 MAD2L1 4085
Affinity Capture-MS Homo sapiens
96 PSMB3 5691
Co-fractionation Homo sapiens
97 RBM14 10432
Co-fractionation Homo sapiens
98 CHERP 10523
Affinity Capture-MS Homo sapiens
99 KIF14 9928
Affinity Capture-MS Homo sapiens
100 PRPS2 5634
Affinity Capture-MS Homo sapiens
101 HSPA8 3312
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
102 LSM2 57819
Affinity Capture-MS Homo sapiens
103 RBMX 27316
Co-fractionation Homo sapiens
104 VTN 7448
Co-fractionation Homo sapiens
105 FSCN1 6624
Affinity Capture-MS Homo sapiens
106 CHMP4C 92421
Affinity Capture-MS Homo sapiens
107 ZMAT3  
Affinity Capture-MS Homo sapiens
108 WBP4  
Reconstituted Complex Homo sapiens
109 STAT5A 6776
Affinity Capture-MS Homo sapiens
110 P4HA1 5033
Affinity Capture-MS Homo sapiens
111 UTP14A 10813
Co-fractionation Homo sapiens
112 ERH 2079
Affinity Capture-MS Homo sapiens
113 RBM12B  
Co-fractionation Homo sapiens
114 PPIH 10465
Affinity Capture-MS Homo sapiens
115 CCDC6 8030
Co-fractionation Homo sapiens
116 TXNL4A 10907
Affinity Capture-MS Homo sapiens
117 SF3B6 51639
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
118 QPRT 23475
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
119 CST6  
Affinity Capture-MS Homo sapiens
120 WDR61 80349
Affinity Capture-MS Homo sapiens
121 MSX2  
Affinity Capture-MS Homo sapiens
122 TRA2A 29896
Co-fractionation Homo sapiens
123 SMEK1 55671
Co-fractionation Homo sapiens
124 RBM7  
Affinity Capture-MS Homo sapiens
125 PSMC1 5700
Co-fractionation Homo sapiens
126 ACIN1 22985
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
127 SNRNP40 9410
Affinity Capture-MS Homo sapiens
128 SRRT 51593
Affinity Capture-MS Homo sapiens
129 HIST1H3E 8353
Affinity Capture-MS Homo sapiens
130 SNRNP200 23020
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
131 ALDH18A1 5832
Affinity Capture-MS Homo sapiens
132 SNRPB 6628
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
133 CCDC12  
Affinity Capture-MS Homo sapiens
134 PABPC1 26986
Co-fractionation Homo sapiens
135 SNRPD1 6632
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
136 MYH9 4627
Cross-Linking-MS (XL-MS) Homo sapiens
137 PPP1R8 5511
Affinity Capture-MS Homo sapiens
138 DDX5 1655
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
139 NTRK1 4914
Affinity Capture-MS Homo sapiens
140 ACTL6A 86
Affinity Capture-MS Homo sapiens
141 ARHGAP11A  
Affinity Capture-MS Homo sapiens
142 U2AF2 11338
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
143 SYNE1 23345
Cross-Linking-MS (XL-MS) Homo sapiens
144 TOX4  
Co-fractionation Homo sapiens
145 TRIP10 9322
Co-fractionation Homo sapiens
146 DYNC2H1 79659
Cross-Linking-MS (XL-MS) Homo sapiens
147 LUC7L2 51631
Affinity Capture-MS Homo sapiens
148 SNRPN 6638
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
149 PLEKHG7  
Affinity Capture-MS Homo sapiens
150 RPA4  
Proximity Label-MS Homo sapiens
151 ENO1 2023
Affinity Capture-RNA Homo sapiens
152 FNBP1 23048
Co-fractionation Homo sapiens
153 SNRNP27  
Affinity Capture-MS Homo sapiens
154 ZRSR2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
155 MAGOH 4116
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
156 TRMT2A 27037
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
157 Arhgap18  
Affinity Capture-MS Mus musculus
158 DDX39B 7919
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
159 OCRL 4952
Affinity Capture-MS Homo sapiens
160 SND1 27044
Affinity Capture-MS Homo sapiens
161 PRPF31 26121
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
162 CEBPA  
Protein-peptide Homo sapiens
163 CYLD  
Affinity Capture-MS Homo sapiens
164 SF3A3 10946
Two-hybrid Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Far Western Homo sapiens
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
165 U2AF1 7307
Co-fractionation Homo sapiens
166 GPATCH11  
Affinity Capture-MS Homo sapiens
167 TRA2B 6434
Affinity Capture-MS Homo sapiens
168 RBM10  
Two-hybrid Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Two-hybrid Homo sapiens
169 SNRPB2 6629
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
170 THOC7 80145
Affinity Capture-MS Homo sapiens
171 SCARNA22  
Affinity Capture-RNA Homo sapiens
172 ANLN 54443
Affinity Capture-MS Homo sapiens
173 TRIM21 6737
Affinity Capture-MS Homo sapiens
174 BCLAF1 9774
Affinity Capture-MS Homo sapiens
175 RBBP6 5930
Affinity Capture-MS Homo sapiens
176 UBE2N 7334
Affinity Capture-MS Homo sapiens
177 SF3B2 10992
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
178 ZBTB2 57621
Affinity Capture-MS Homo sapiens
179 FNBP1L 54874
Co-fractionation Homo sapiens
180 PRPF4B 8899
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
181 SUGP1  
Affinity Capture-MS Homo sapiens
182 PPP4R2  
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
183 CUL3 8452
Affinity Capture-MS Homo sapiens
184 KDM4D  
Affinity Capture-MS Homo sapiens
185 DOCK8 81704
Affinity Capture-MS Homo sapiens
186 BAG1 573
Affinity Capture-MS Homo sapiens
187 NR3C1 2908
Co-fractionation Homo sapiens
188 BAG2 9532
Affinity Capture-MS Homo sapiens
189 SMARCC2 6601
Co-fractionation Homo sapiens
190 SIRT7  
Affinity Capture-MS Homo sapiens
191 CD2BP2 10421
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
192 IFI16 3428
Affinity Capture-MS Homo sapiens
193 PLRG1 5356
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
194 NCBP2 22916
Affinity Capture-MS Homo sapiens
195 SRSF1 6426
Co-fractionation Homo sapiens
196 YLPM1 56252
Affinity Capture-MS Homo sapiens
197 DNAJC8 22826
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
198 ATG12  
Affinity Capture-MS Homo sapiens
199 WDR82 80335
Affinity Capture-MS Homo sapiens
200 SETD2  
Affinity Capture-MS Homo sapiens
201 SF1 7536
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
202 XAB2 56949
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
203 SRSF5 6430
Co-fractionation Homo sapiens
204 CYP1A1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
205 SYNCRIP 10492
Affinity Capture-MS Homo sapiens
206 THOC5 8563
Affinity Capture-MS Homo sapiens
207 MCM4 4173
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
208 FUS 2521
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
209 Mphosph9  
Affinity Capture-MS Mus musculus
210 CENPM  
Affinity Capture-MS Homo sapiens
211 PSMD7 5713
Co-fractionation Homo sapiens
212 SUZ12  
Affinity Capture-MS Homo sapiens
213 SART1 9092
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
214 NXF1 10482
Affinity Capture-RNA Homo sapiens
215 ERP44 23071
Affinity Capture-MS Homo sapiens
216 TRIM55  
Co-fractionation Homo sapiens
217 TPBG 7162
Co-fractionation Homo sapiens
218 ACTR1A 10121
Co-fractionation Homo sapiens
219 PATL1 219988
Co-fractionation Homo sapiens
220 IL7R  
Protein-RNA Homo sapiens
221 MFAP1  
Affinity Capture-MS Homo sapiens
222 PRPF19 27339
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
223 MYC  
Affinity Capture-MS Homo sapiens
224 RPA3 6119
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
225 PPWD1 23398
Affinity Capture-MS Homo sapiens
226 ZC3H18  
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
227 EMC2 9694
Affinity Capture-MS Homo sapiens
228 EGFR 1956
Negative Genetic Homo sapiens
229 PNN 5411
Affinity Capture-MS Homo sapiens
230 EPB41 2035
Co-fractionation Homo sapiens
231 PHF5A 84844
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
232 THOC1 9984
Affinity Capture-MS Homo sapiens
233 VRK2 7444
Affinity Capture-MS Homo sapiens
234 PRPF40A 55660
Two-hybrid Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
235 SNW1 22938
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
236 Junb  
Affinity Capture-MS Mus musculus
237 DDRGK1 65992
Affinity Capture-MS Homo sapiens
238 RNF2  
Affinity Capture-MS Homo sapiens
239 SF3B3 23450
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
240 FOXQ1  
Affinity Capture-MS Homo sapiens
241 XRCC3  
Affinity Capture-MS Homo sapiens
242 SLU7  
Co-fractionation Homo sapiens
243 HSPD1 3329
Co-fractionation Homo sapiens
244 ZNF318 24149
Affinity Capture-MS Homo sapiens
245 GAS7  
Reconstituted Complex Homo sapiens
246 ENTHD2  
Affinity Capture-MS Homo sapiens
247 ZC3H11A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
248 PSMB1 5689
Co-fractionation Homo sapiens
249 SUPT16H 11198
Co-fractionation Homo sapiens
250 TAF4 6874
Affinity Capture-MS Homo sapiens
251 RAE1 8480
Affinity Capture-MS Homo sapiens
252 RBM17 84991
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
253 HUWE1 10075
Affinity Capture-MS Homo sapiens
254 ISY1-RAB43 100534599
Co-fractionation Homo sapiens
255 U2SURP 23350
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
256 PA2G4 5036
Affinity Capture-MS Homo sapiens
257 DDX46 9879
Co-fractionation Homo sapiens
258 HTATSF1 27336
Affinity Capture-MS Homo sapiens
259 PAXBP1  
Affinity Capture-MS Homo sapiens
260 DHX15 1665
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
261 HNRNPA3 220988
Affinity Capture-MS Homo sapiens
262 MRPL42  
Affinity Capture-MS Homo sapiens
263 FHL1 2273
Affinity Capture-MS Homo sapiens
264 SRRM2 23524
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
265 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
266 EFTUD2 9343
Affinity Capture-MS Homo sapiens
267 BCAS2 10286
Affinity Capture-MS Homo sapiens
268 PARP1 142
Proximity Label-MS Homo sapiens
269 WDR77 79084
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
270 TTC33  
Affinity Capture-MS Homo sapiens
271 CHTOP  
Affinity Capture-MS Homo sapiens
272 TP53 7157
Affinity Capture-MS Homo sapiens
273 RBM25 58517
Affinity Capture-MS Homo sapiens
274 WWOX 51741
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
275 TCERG1 10915
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
276 MCM5 4174
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
277 SF3B4 10262
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
278 EIF4G1 1981
Co-fractionation Homo sapiens
279 TSKS  
Co-fractionation Homo sapiens
280 RPA1 6117
Affinity Capture-MS Homo sapiens
281 MEN1 4221
Affinity Capture-MS Homo sapiens
282 HNRNPA2B1 3181
Co-fractionation Homo sapiens
283 SNRPA 6626
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
284 HNRNPM 4670
Co-fractionation Homo sapiens
285 SMURF1 57154
Affinity Capture-MS Homo sapiens
286 THRAP3 9967
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
287 RBM39 9584
Affinity Capture-MS Homo sapiens
288 PRMT1 3276
Affinity Capture-MS Homo sapiens
289 SNRPD2 6633
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
290 CDC40  
Affinity Capture-MS Homo sapiens
291 Sf3a1 67465
Affinity Capture-MS Mus musculus
292 NSRP1  
Affinity Capture-MS Homo sapiens
293 EIF4A3 9775
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
294 CCDC97  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
295 CWC15  
Affinity Capture-MS Homo sapiens
296 HDAC5 10014
Affinity Capture-MS Homo sapiens
297 HNRNPK 3190
Co-fractionation Homo sapiens
298 WIF1 11197
Affinity Capture-MS Homo sapiens
299 DYNC1H1 1778
Co-fractionation Homo sapiens
300 UFL1 23376
Affinity Capture-MS Homo sapiens
301 KDM4C  
Affinity Capture-MS Homo sapiens
302 DDX39A 10212
Affinity Capture-MS Homo sapiens
303 RBFOX2 23543
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
304 USP30  
Affinity Capture-MS Homo sapiens
305 IDH2 3418
Affinity Capture-MS Homo sapiens
306 LSM7  
Affinity Capture-MS Homo sapiens
307 MOV10 4343
Affinity Capture-RNA Homo sapiens
308 ALYREF 10189
Affinity Capture-MS Homo sapiens
309 PSMA5 5686
Co-fractionation Homo sapiens
310 SRSF9 8683
Affinity Capture-MS Homo sapiens
311 GM2A 2760
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
312 SNRNP70 6625
Co-fractionation Homo sapiens
313 ARHGAP20  
Affinity Capture-MS Homo sapiens
314 GAPVD1 26130
Co-fractionation Homo sapiens
315 SRSF7 6432
Co-fractionation Homo sapiens
316 PINK1  
Affinity Capture-MS Homo sapiens
317 RNPS1 10921
Affinity Capture-MS Homo sapiens
318 ANXA5 308
Affinity Capture-MS Homo sapiens
319 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
320 PRPF6 24148
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
321 SMNDC1  
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
322 DDX42 11325
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
323 LDLR 3949
Negative Genetic Homo sapiens
324 LSM6 11157
Affinity Capture-MS Homo sapiens
325 PRPF4 9128
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
326 CUL7 9820
Affinity Capture-MS Homo sapiens
327 KRAS 3845
Negative Genetic Homo sapiens
328 HNRNPU 3192
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
329 PSMD1 5707
Co-fractionation Homo sapiens
330 VASN 114990
Co-fractionation Homo sapiens
331 SNRPA1 6627
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
332 THOC6 79228
Affinity Capture-MS Homo sapiens
333 SMCHD1 23347
Affinity Capture-MS Homo sapiens
334 PCNP 57092
Affinity Capture-MS Homo sapiens
335 SMARCC1 6599
Co-fractionation Homo sapiens
336 ZNF830  
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
337 EP300 2033
Affinity Capture-MS Homo sapiens
338 CDC5L 988
Affinity Capture-MS Homo sapiens
Co-purification Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
339 RBM8A 9939
Affinity Capture-MS Homo sapiens
340 CTSH 1512
Affinity Capture-MS Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here