Gene description for ANOS1
Gene name anosmin 1
Gene symbol ANOS1
Other names/aliases ADMLX
HH1
HHA
KAL
KAL1
KALIG-1
KMS
WFDC19
Species Homo sapiens
 Database cross references - ANOS1
ExoCarta ExoCarta_3730
Vesiclepedia VP_3730
Entrez Gene 3730
HGNC 6211
MIM 300836
UniProt P23352  
 ANOS1 identified in exosomes derived from the following tissue/cell type
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
 Gene ontology annotations for ANOS1
Molecular Function
    serine-type endopeptidase inhibitor activity GO:0004867 IEA
    extracellular matrix structural constituent GO:0005201 TAS
    protein binding GO:0005515 IPI
    heparin binding GO:0008201 IEA
Biological Process
    chemotaxis GO:0006935 IEA
    cell adhesion GO:0007155 IEA
    axon guidance GO:0007411 TAS
    neuron differentiation GO:0030182 IBA
Subcellular Localization
    extracellular region GO:0005576 TAS
    extracellular space GO:0005615 TAS
    plasma membrane GO:0005886 IEA
    cell surface GO:0009986 IBA
    extracellular matrix GO:0031012 TAS
 Experiment description of studies that identified ANOS1 in exosomes
1
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for ANOS1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 GNL2 29889
Affinity Capture-MS Homo sapiens
2 ZNF668  
Affinity Capture-MS Homo sapiens
3 RPL26L1 51121
Affinity Capture-MS Homo sapiens
4 TRMT1L 81627
Affinity Capture-MS Homo sapiens
5 WDR3  
Affinity Capture-MS Homo sapiens
6 ZNF346  
Affinity Capture-MS Homo sapiens
7 KIAA0020 9933
Affinity Capture-MS Homo sapiens
8 SRPK2 6733
Affinity Capture-MS Homo sapiens
9 UTP11L  
Affinity Capture-MS Homo sapiens
10 TOP3B 8940
Affinity Capture-MS Homo sapiens
11 RPL37A 6168
Affinity Capture-MS Homo sapiens
12 ZNF708  
Affinity Capture-MS Homo sapiens
13 NMNAT1  
Affinity Capture-MS Homo sapiens
14 URB2  
Affinity Capture-MS Homo sapiens
15 SRFBP1  
Affinity Capture-MS Homo sapiens
16 BUD13  
Affinity Capture-MS Homo sapiens
17 ZNF92  
Affinity Capture-MS Homo sapiens
18 ZBTB1  
Affinity Capture-MS Homo sapiens
19 KMT2A  
Affinity Capture-MS Homo sapiens
20 PWP2 5822
Affinity Capture-MS Homo sapiens
21 WDR36 134430
Affinity Capture-MS Homo sapiens
22 USP36  
Affinity Capture-MS Homo sapiens
23 RSBN1L  
Affinity Capture-MS Homo sapiens
24 NSA2  
Affinity Capture-MS Homo sapiens
25 LLPH  
Affinity Capture-MS Homo sapiens
26 DDX24 57062
Affinity Capture-MS Homo sapiens
27 ZNF724P  
Affinity Capture-MS Homo sapiens
28 ZSCAN21  
Affinity Capture-MS Homo sapiens
29 ANOS1 3730
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
30 TTF1  
Affinity Capture-MS Homo sapiens
31 DDX51  
Affinity Capture-MS Homo sapiens
32 ZNF16  
Affinity Capture-MS Homo sapiens
33 ZNF107  
Affinity Capture-MS Homo sapiens
34 SRP68 6730
Affinity Capture-MS Homo sapiens
35 ZNF100  
Affinity Capture-MS Homo sapiens
36 RRP8  
Affinity Capture-MS Homo sapiens
37 NSD1  
Affinity Capture-MS Homo sapiens
38 C12orf43  
Affinity Capture-MS Homo sapiens
39 FGFR1 2260
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
40 ZNF184  
Affinity Capture-MS Homo sapiens
41 CCDC86  
Affinity Capture-MS Homo sapiens
42 TFB1M  
Affinity Capture-MS Homo sapiens
43 EIF2AK2 5610
Affinity Capture-MS Homo sapiens
44 DDX31  
Affinity Capture-MS Homo sapiens
45 ZKSCAN8  
Affinity Capture-MS Homo sapiens
46 HIST2H2AB 317772
Affinity Capture-MS Homo sapiens
47 DDX21 9188
Affinity Capture-MS Homo sapiens
48 RBM28 55131
Affinity Capture-MS Homo sapiens
49 BLM 641
Affinity Capture-MS Homo sapiens
50 STAU1 6780
Affinity Capture-MS Homo sapiens
51 APOBEC3C 27350
Affinity Capture-MS Homo sapiens
52 DDX10  
Affinity Capture-MS Homo sapiens
53 SRBD1  
Affinity Capture-MS Homo sapiens
54 REXO4  
Affinity Capture-MS Homo sapiens
55 HIST1H1C 3006
Affinity Capture-MS Homo sapiens
56 ZFP91 80829
Affinity Capture-MS Homo sapiens
57 RRP1B 23076
Affinity Capture-MS Homo sapiens
58 SPTY2D1  
Affinity Capture-MS Homo sapiens
59 DNTTIP2  
Affinity Capture-MS Homo sapiens
60 USP28 57646
Affinity Capture-MS Homo sapiens
61 PURB 5814
Affinity Capture-MS Homo sapiens
62 TEFM  
Affinity Capture-MS Homo sapiens
63 BMS1  
Affinity Capture-MS Homo sapiens
64 SPATS2L 26010
Affinity Capture-MS Homo sapiens
65 RPLP2 6181
Affinity Capture-MS Homo sapiens
66 NOC3L 64318
Affinity Capture-MS Homo sapiens
67 ZC3HAV1 56829
Affinity Capture-MS Homo sapiens
68 ZBTB24  
Affinity Capture-MS Homo sapiens
69 NAT10 55226
Affinity Capture-MS Homo sapiens
70 TAF1B  
Affinity Capture-MS Homo sapiens
71 Lama1  
Reconstituted Complex Mus musculus
72 RPL3 6122
Affinity Capture-MS Homo sapiens
73 ISG20L2 81875
Affinity Capture-MS Homo sapiens
74 EBNA1BP2 10969
Affinity Capture-MS Homo sapiens
75 BBX 56987
Affinity Capture-MS Homo sapiens
76 PDCD11 22984
Affinity Capture-MS Homo sapiens
77 SUZ12  
Affinity Capture-MS Homo sapiens
78 SDC2 6383
Affinity Capture-Western Homo sapiens
79 FN1 2335
Reconstituted Complex Homo sapiens
80 NTHL1  
Affinity Capture-MS Homo sapiens
81 DHX57 90957
Affinity Capture-MS Homo sapiens
82 ZNF512  
Affinity Capture-MS Homo sapiens
83 CEBPZ  
Affinity Capture-MS Homo sapiens
84 ZCCHC6 79670
Affinity Capture-MS Homo sapiens
85 DDX54 79039
Affinity Capture-MS Homo sapiens
86 BAZ1A 11177
Affinity Capture-MS Homo sapiens
87 PATZ1  
Affinity Capture-MS Homo sapiens
88 ZFP62  
Affinity Capture-MS Homo sapiens
89 NOL6 65083
Affinity Capture-MS Homo sapiens
90 UTP3 57050
Affinity Capture-MS Homo sapiens
91 FTSJ3 117246
Affinity Capture-MS Homo sapiens
92 TAF1A  
Affinity Capture-MS Homo sapiens
93 DDX55  
Affinity Capture-MS Homo sapiens
94 NDNF  
Affinity Capture-MS Homo sapiens
95 NGDN  
Affinity Capture-MS Homo sapiens
96 C3orf17  
Affinity Capture-MS Homo sapiens
97 RRP7A 27341
Affinity Capture-MS Homo sapiens
98 NIP7 51388
Affinity Capture-MS Homo sapiens
99 EXOSC10 5394
Affinity Capture-MS Homo sapiens
100 ZNF624 57547
Affinity Capture-MS Homo sapiens
101 C8orf33 65265
Affinity Capture-MS Homo sapiens
102 RRP36 88745
Affinity Capture-MS Homo sapiens
103 TSHZ3  
Affinity Capture-MS Homo sapiens
104 SRRM1 10250
Affinity Capture-MS Homo sapiens
105 RRS1 23212
Affinity Capture-MS Homo sapiens
106 ZNF273  
Affinity Capture-MS Homo sapiens
107 PRDM15  
Affinity Capture-MS Homo sapiens
108 MINA 84864
Affinity Capture-MS Homo sapiens
109 NOL10  
Affinity Capture-MS Homo sapiens
110 POP4 10775
Affinity Capture-MS Homo sapiens
111 KNOP1 400506
Affinity Capture-MS Homo sapiens
112 LENG8  
Affinity Capture-MS Homo sapiens
113 ZNF48  
Affinity Capture-MS Homo sapiens
114 URB1 9875
Affinity Capture-MS Homo sapiens
115 SRP72 6731
Affinity Capture-MS Homo sapiens
116 THAP11 57215
Affinity Capture-MS Homo sapiens
117 TBL3 10607
Affinity Capture-MS Homo sapiens
118 TAF1D  
Affinity Capture-MS Homo sapiens
119 Lamb2 16779
Reconstituted Complex Mus musculus
120 ZNF7  
Affinity Capture-MS Homo sapiens
121 TRIP12 9320
Affinity Capture-MS Homo sapiens
122 DDX27 55661
Affinity Capture-MS Homo sapiens
123 GZF1  
Affinity Capture-MS Homo sapiens
124 ZNF691  
Affinity Capture-MS Homo sapiens
125 NOC2L 26155
Affinity Capture-MS Homo sapiens
126 GTPBP4 23560
Affinity Capture-MS Homo sapiens
127 HNRNPLL 92906
Affinity Capture-MS Homo sapiens
128 YTHDC2 64848
Affinity Capture-MS Homo sapiens
129 ZNF768 79724
Affinity Capture-MS Homo sapiens
130 AKAP17A  
Affinity Capture-MS Homo sapiens
131 ZNF800  
Affinity Capture-MS Homo sapiens
132 TAF1C  
Affinity Capture-MS Homo sapiens
133 DDX42 11325
Co-fractionation Homo sapiens
134 ZNF629 23361
Affinity Capture-MS Homo sapiens
135 RPL36AL 6166
Affinity Capture-MS Homo sapiens
136 RBM34  
Affinity Capture-MS Homo sapiens
137 ZNF431  
Affinity Capture-MS Homo sapiens
138 NVL  
Affinity Capture-MS Homo sapiens
139 Lamb1 16777
Reconstituted Complex Mus musculus
140 RPL17 6139
Affinity Capture-MS Homo sapiens
141 HERC5 51191
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



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