Gene description for BAX
Gene name BCL2-associated X protein
Gene symbol BAX
Other names/aliases BCL2L4
Species Homo sapiens
 Database cross references - BAX
ExoCarta ExoCarta_581
Vesiclepedia VP_581
Entrez Gene 581
HGNC 959
MIM 600040
UniProt Q07812  
 BAX identified in sEVs derived from the following tissue/cell type
B cells 20458337    
B cells 20458337    
B cells 20458337    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Mesenchymal stem cells 36408942    
 Gene ontology annotations for BAX
Molecular Function
    protein binding GO:0005515 IPI
    lipid binding GO:0008289 IDA
    channel activity GO:0015267 IBA
    channel activity GO:0015267 IDA
    Hsp70 protein binding GO:0030544 IEA
    identical protein binding GO:0042802 IPI
    protein homodimerization activity GO:0042803 IDA
    protein heterodimerization activity GO:0046982 IPI
    BH3 domain binding GO:0051434 IDA
    BH3 domain binding GO:0051434 IPI
Biological Process
    ovarian follicle development GO:0001541 IEA
    neuron migration GO:0001764 IEA
    T cell homeostatic proliferation GO:0001777 IEA
    B cell homeostasis GO:0001782 IEA
    B cell apoptotic process GO:0001783 IDA
    kidney development GO:0001822 IEA
    release of cytochrome c from mitochondria GO:0001836 IBA
    release of cytochrome c from mitochondria GO:0001836 IDA
    blood vessel remodeling GO:0001974 IEA
    myeloid cell homeostasis GO:0002262 IEA
    B cell negative selection GO:0002352 IEA
    B cell homeostatic proliferation GO:0002358 IEA
    positive regulation of B cell apoptotic process GO:0002904 IEA
    glycosphingolipid metabolic process GO:0006687 IEA
    regulation of nitrogen utilization GO:0006808 IEA
    apoptotic process GO:0006915 IDA
    apoptotic process GO:0006915 IMP
    apoptotic process GO:0006915 NAS
    germ cell development GO:0007281 IEA
    mitochondrial fusion GO:0008053 IBA
    mitochondrial fusion GO:0008053 IDA
    extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 IC
    intrinsic apoptotic signaling pathway in response to DNA damage GO:0008630 IBA
    intrinsic apoptotic signaling pathway in response to DNA damage GO:0008630 IDA
    apoptotic mitochondrial changes GO:0008637 IDA
    fertilization GO:0009566 IEA
    response to toxic substance GO:0009636 IDA
    response to salt stress GO:0009651 IEA
    establishment or maintenance of transmembrane electrochemical gradient GO:0010248 IDA
    response to gamma radiation GO:0010332 IEA
    positive regulation of calcium ion transport into cytosol GO:0010524 IEA
    negative regulation of mitochondrial membrane potential GO:0010917 IDA
    hypothalamus development GO:0021854 IEA
    cerebral cortex development GO:0021987 IEA
    positive regulation of protein-containing complex assembly GO:0031334 IDA
    negative regulation of protein binding GO:0032091 IDA
    endoplasmic reticulum calcium ion homeostasis GO:0032469 TAS
    negative regulation of endoplasmic reticulum calcium ion concentration GO:0032471 IEA
    release of matrix enzymes from mitochondria GO:0032976 IDA
    regulation of mammary gland epithelial cell proliferation GO:0033599 IEA
    cellular response to unfolded protein GO:0034620 TAS
    cellular response to UV GO:0034644 IEA
    ectopic germ cell programmed cell death GO:0035234 IEA
    odontogenesis of dentin-containing tooth GO:0042475 IEA
    regulation of apoptotic process GO:0042981 IDA
    positive regulation of apoptotic process GO:0043065 IDA
    positive regulation of apoptotic process GO:0043065 IMP
    negative regulation of neuron apoptotic process GO:0043524 IEA
    positive regulation of neuron apoptotic process GO:0043525 IBA
    positive regulation of neuron apoptotic process GO:0043525 IDA
    mitochondrial fragmentation involved in apoptotic process GO:0043653 IDA
    development of secondary sexual characteristics GO:0045136 IEA
    retinal cell programmed cell death GO:0046666 IEA
    positive regulation of developmental pigmentation GO:0048087 IEA
    negative regulation of fibroblast proliferation GO:0048147 IEA
    spermatid differentiation GO:0048515 IEA
    post-embryonic camera-type eye morphogenesis GO:0048597 IEA
    response to axon injury GO:0048678 IEA
    homeostasis of number of cells within a tissue GO:0048873 IEA
    protein insertion into mitochondrial membrane GO:0051204 IEA
    release of sequestered calcium ion into cytosol GO:0051209 IEA
    positive regulation of release of sequestered calcium ion into cytosol GO:0051281 IEA
    regulation of cell cycle GO:0051726 IEA
    regulation of mitochondrial membrane potential GO:0051881 IDA
    Sertoli cell proliferation GO:0060011 IEA
    retina development in camera-type eye GO:0060041 IEA
    apoptotic process involved in mammary gland involution GO:0060057 IEA
    positive regulation of apoptotic process involved in mammary gland involution GO:0060058 IEA
    vagina development GO:0060068 IEA
    calcium ion transport into cytosol GO:0060402 IEA
    intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 TAS
    thymocyte apoptotic process GO:0070242 IEA
    intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 IEA
    positive regulation of release of cytochrome c from mitochondria GO:0090200 IDA
    positive regulation of release of cytochrome c from mitochondria GO:0090200 IMP
    motor neuron apoptotic process GO:0097049 IEA
    apoptotic signaling pathway GO:0097190 IDA
    extrinsic apoptotic signaling pathway GO:0097191 IDA
    extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 IBA
    intrinsic apoptotic signaling pathway GO:0097193 IDA
    execution phase of apoptosis GO:0097194 IMP
    supramolecular fiber organization GO:0097435 IDA
    cellular response to virus GO:0098586 IDA
    positive regulation of mitochondrial membrane permeability involved in apoptotic process GO:1902110 IEA
    apoptotic process involved in blood vessel morphogenesis GO:1902262 IEA
    apoptotic process involved in embryonic digit morphogenesis GO:1902263 IEA
    regulation of mitochondrial membrane permeability involved in programmed necrotic cell death GO:1902445 IEA
    positive regulation of apoptotic DNA fragmentation GO:1902512 IMP
    positive regulation of IRE1-mediated unfolded protein response GO:1903896 TAS
    epithelial cell apoptotic process GO:1904019 IEA
    positive regulation of epithelial cell apoptotic process GO:1904037 IEA
    B cell receptor apoptotic signaling pathway GO:1990117 IDA
    positive regulation of reproductive process GO:2000243 IEA
    positive regulation of motor neuron apoptotic process GO:2000673 IEA
    negative regulation of apoptotic signaling pathway GO:2001234 IEA
    positive regulation of intrinsic apoptotic signaling pathway GO:2001244 IMP
Subcellular Localization
    nucleus GO:0005634 IDA
    nucleus GO:0005634 IMP
    nuclear envelope GO:0005635 IDA
    cytoplasm GO:0005737 IDA
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 IDA
    mitochondrial outer membrane GO:0005741 IBA
    mitochondrial outer membrane GO:0005741 IDA
    mitochondrial outer membrane GO:0005741 TAS
    mitochondrial permeability transition pore complex GO:0005757 IDA
    endoplasmic reticulum GO:0005783 IDA
    endoplasmic reticulum membrane GO:0005789 IDA
    cytosol GO:0005829 IDA
    cytosol GO:0005829 TAS
    membrane GO:0016020 HDA
    pore complex GO:0046930 IDA
    extracellular exosome GO:0070062 HDA
    cell periphery GO:0071944 IDA
    Bcl-2 family protein complex GO:0097136 IDA
    BAX complex GO:0097144 IDA
    BAK complex GO:0097145 IDA
 Experiment description of studies that identified BAX in sEVs
1
Experiment ID 79
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 1
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
2
Experiment ID 80
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
3
Experiment ID 81
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
4
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
7
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
8
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
9
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
10
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
11
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
12
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for BAX
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UBE2H 7328
Affinity Capture-MS Homo sapiens
2 XIAP  
Affinity Capture-Western Homo sapiens
3 GUK1 2987
Co-fractionation Homo sapiens
4 PKM 5315
Co-fractionation Homo sapiens
5 MOAP1  
Affinity Capture-Western Homo sapiens
6 C9orf78 51759
Affinity Capture-MS Homo sapiens
7 PARK7 11315
Reconstituted Complex Homo sapiens
8 TOMM22 56993
Affinity Capture-Western Homo sapiens
9 KIAA1429 25962
Affinity Capture-MS Homo sapiens
10 PARK2  
Affinity Capture-MS Homo sapiens
11 WDR76  
Co-purification Homo sapiens
Affinity Capture-MS Homo sapiens
12 COQ9  
Affinity Capture-MS Homo sapiens
13 CASP3 836
Co-fractionation Homo sapiens
14 LONRF3  
Co-fractionation Homo sapiens
15 PNPLA6 10908
Affinity Capture-MS Homo sapiens
16 ATAD5  
Affinity Capture-MS Homo sapiens
17 PRDX2 7001
Co-fractionation Homo sapiens
18 GIMAP5  
Affinity Capture-Western Homo sapiens
19 SERPINH1 871
Co-fractionation Homo sapiens
20 SLC25A46 91137
Proximity Label-MS Homo sapiens
21 TOMM40 10452
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
22 NSFL1C 55968
Affinity Capture-MS Homo sapiens
23 FGFR1 2260
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
24 C18orf21  
Affinity Capture-MS Homo sapiens
25 PSMC3 5702
Affinity Capture-Western Homo sapiens
26 GEMIN2 8487
Affinity Capture-MS Homo sapiens
27 BCL2L11  
Affinity Capture-MS Homo sapiens
28 MEPCE 56257
Affinity Capture-MS Homo sapiens
29 CLU 1191
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
30 USP30  
Affinity Capture-Western Homo sapiens
31 BDP1  
Affinity Capture-MS Homo sapiens
32 MKRN2 23609
Affinity Capture-RNA Homo sapiens
33 SREBF2 6721
Negative Genetic Homo sapiens
34 PMAIP1  
Affinity Capture-Western Homo sapiens
35 VCP 7415
Affinity Capture-MS Homo sapiens
36 BCL2L2 599
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
37 YWHAQ 10971
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Dosage Rescue Homo sapiens
38 BCL2  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
39 ANAPC4 29945
Affinity Capture-MS Homo sapiens
40 MAPK8 5599
Affinity Capture-Western Homo sapiens
41 ITCH 83737
Affinity Capture-Western Homo sapiens
42 TXN2 25828
Co-fractionation Homo sapiens
43 BAG3 9531
Affinity Capture-MS Homo sapiens
44 BBC3  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
45 C15orf48  
Affinity Capture-MS Homo sapiens
46 BCL2L12 83596
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
47 RNF144B  
Affinity Capture-Western Homo sapiens
48 BAX 581
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
49 ZBTB24  
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
50 CRYAB 1410
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
51 CRYAA 1409
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
52 UHRF2  
Far Western Homo sapiens
53 HSD17B10 3028
Affinity Capture-MS Homo sapiens
54 YY1 7528
Affinity Capture-MS Homo sapiens
55 BCL2L15  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
56 OCIAD1 54940
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
57 PCBP1 5093
Co-fractionation Homo sapiens
58 CASP9 842
Co-fractionation Homo sapiens
59 RPA3 6119
Proximity Label-MS Homo sapiens
60 NIN 51199
Affinity Capture-MS Homo sapiens
61 GSTK1 373156
Co-fractionation Homo sapiens
62 HSPA4 3308
Affinity Capture-Western Homo sapiens
63 PSMC5 5705
Affinity Capture-Western Homo sapiens
64 VDAC1 7416
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
65 SEPT7 989
Dosage Rescue Homo sapiens
66 HSPD1 3329
Affinity Capture-Western Homo sapiens
67 AKAP1 8165
Proximity Label-MS Homo sapiens
68 XRCC5 7520
Affinity Capture-Western Homo sapiens
69 C6orf222  
Affinity Capture-MS Homo sapiens
70 SNCA 6622
Co-localization Homo sapiens
71 BCL2A1  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
72 LIG3 3980
Affinity Capture-MS Homo sapiens
73 BAD  
Affinity Capture-Western Homo sapiens
74 CASP7  
Co-fractionation Homo sapiens
75 TP53 7157
Co-localization Homo sapiens
76 FCGRT 2217
Co-fractionation Homo sapiens
77 HDAC6 10013
Affinity Capture-Western Homo sapiens
78 PPM1J  
Affinity Capture-MS Homo sapiens
79 MCL1 4170
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Dosage Rescue Homo sapiens
Two-hybrid Homo sapiens
Co-crystal Structure Homo sapiens
Affinity Capture-Western Homo sapiens
80 CASP8 841
Co-fractionation Homo sapiens
81 BID  
Co-localization Homo sapiens
82 FBXL20 84961
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
83 BAK1 578
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
84 ERCC6  
Affinity Capture-MS Homo sapiens
85 BCL2L1 598
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
FRET Homo sapiens
Affinity Capture-MS Homo sapiens
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Co-crystal Structure Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Dosage Rescue Homo sapiens
86 SLC25A4 291
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
87 LRRK2 120892
Affinity Capture-Western Homo sapiens
88 SERPINB12 89777
Affinity Capture-MS Homo sapiens
89 SH3GLB1 51100
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
90 Bak1  
Affinity Capture-Western Rattus norvegicus
91 PRDX1 5052
Co-fractionation Homo sapiens
92 XRCC6 2547
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
93 CYCS 54205
Co-fractionation Homo sapiens
94 PRSS23 11098
Affinity Capture-MS Homo sapiens
95 KCNA3  
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
96 BCL2L10  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
97 EDRF1  
Affinity Capture-MS Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here