Gene description for ZNF207
Gene name zinc finger protein 207
Gene symbol ZNF207
Other names/aliases BuGZ
Species Homo sapiens
 Database cross references - ZNF207
ExoCarta ExoCarta_7756
Entrez Gene 7756
HGNC 12998
MIM 603428
UniProt O43670  
 ZNF207 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
Hepatocytes 26054723    
 Gene ontology annotations for ZNF207
Molecular Function
    zinc ion binding GO:0008270 NAS
    protein binding GO:0005515 IPI
    sequence-specific DNA binding transcription factor activity GO:0003700 NAS
    heparin binding GO:0008201 IEA
    poly(A) RNA binding GO:0044822 IDA
    microtubule binding GO:0008017 IDA
    DNA binding GO:0003677 IEA
Biological Process
    protein stabilization GO:0050821 IMP
    mitotic spindle assembly checkpoint GO:0007094 IMP
    attachment of spindle microtubules to kinetochore GO:0008608 IMP
    mitotic sister chromatid segregation GO:0000070 IMP
    cell division GO:0051301 IEA
    regulation of transcription, DNA-templated GO:0006355 NAS
    regulation of chromosome segregation GO:0051983 IMP
Subcellular Localization
    condensed chromosome kinetochore GO:0000777 IEA
    nucleus GO:0005634 NAS
    kinetochore GO:0000776 IMP
    microtubule GO:0005874 IEA
    nucleolus GO:0005730 IDA
 Experiment description of studies that identified ZNF207 in exosomes
1
Experiment ID 236
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
2
Experiment ID 237
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for ZNF207
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ERBB3 2065
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which ZNF207 is involved
No pathways found





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