Gene description for MAD2L2
Gene name	MAD2 mitotic arrest deficient-like 2 (yeast)
Gene symbol	MAD2L2
Other names/aliases	MAD2B POLZ2 REV7
Species	Homo sapiens
Database cross references - MAD2L2
ExoCarta	ExoCarta_10459
Vesiclepedia	VP_10459
Entrez Gene	10459
HGNC	6764
MIM	604094
UniProt	Q9UI95
MAD2L2 identified in sEVs derived from the following tissue/cell type
Hepatocytes	26054723

Gene ontology annotations for MAD2L2

Molecular Function     protein binding GO:0005515 IPI     JUN kinase binding GO:0008432 IDA     RNA polymerase II-specific DNA-binding transcription factor binding GO:0061629 IPI Biological Process     negative regulation of transcription by RNA polymerase II GO:0000122 IDA     regulation of cell growth GO:0001558 IGI     somatic diversification of immunoglobulins involved in immune response GO:0002208 NAS     double-strand break repair GO:0006302 IGI     actin filament organization GO:0007015 IMP     mitotic spindle assembly checkpoint signaling GO:0007094 TAS     positive regulation of epithelial to mesenchymal transition GO:0010718 IEA     negative regulation of epithelial to mesenchymal transition GO:0010719 IMP     negative regulation of transcription by competitive promoter binding GO:0010944 IMP     positive regulation of peptidyl-serine phosphorylation GO:0033138 IDA     negative regulation of protein catabolic process GO:0042177 IDA     error-prone translesion synthesis GO:0042276 IDA     DNA damage response, signal transduction resulting in transcription GO:0042772 IDA     telomere maintenance in response to DNA damage GO:0043247 NAS     negative regulation of DNA-binding transcription factor activity GO:0043433 IDA     positive regulation of isotype switching GO:0045830 IDA     positive regulation of DNA-templated transcription GO:0045893 IMP     cell division GO:0051301 IEA     negative regulation of canonical Wnt signaling pathway GO:0090090 IMP     positive regulation of extracellular matrix assembly GO:1901203 IEA     negative regulation of ubiquitin protein ligase activity GO:1904667 IDA     negative regulation of double-strand break repair via homologous recombination GO:2000042 IDA     negative regulation of cell-cell adhesion mediated by cadherin GO:2000048 IMP     negative regulation of transcription regulatory region DNA binding GO:2000678 IMP     positive regulation of double-strand break repair via nonhomologous end joining GO:2001034 IDA     positive regulation of double-strand break repair via nonhomologous end joining GO:2001034 NAS Subcellular Localization     chromatin GO:0000785 NAS     nucleus GO:0005634 IDA     nucleoplasm GO:0005654 IDA     nucleoplasm GO:0005654 TAS     anaphase-promoting complex GO:0005680 IDA     chromosome GO:0005694 IC     cytoplasm GO:0005737 IEA     spindle GO:0005819 IDA     zeta DNA polymerase complex GO:0016035 IBA     zeta DNA polymerase complex GO:0016035 IDA     zeta DNA polymerase complex GO:0016035 IPI     site of double-strand break GO:0035861 IC     site of double-strand break GO:0035861 NAS