Gene description for C17orf75
Gene name chromosome 17 open reading frame 75
Gene symbol C17orf75
Other names/aliases NJMU-R1
Species Homo sapiens
 Database cross references - C17orf75
ExoCarta ExoCarta_64149
Vesiclepedia VP_64149
Entrez Gene 64149
HGNC 30173
UniProt Q9HAS0  
 C17orf75 identified in sEVs derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for C17orf75
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    intracellular protein transport GO:0006886 IDA
    vesicle tethering to Golgi GO:0099041 IBA
    vesicle tethering to Golgi GO:0099041 IDA
Subcellular Localization
    Golgi apparatus GO:0005794 IDA
    trans-Golgi network GO:0005802 IBA
    trans-Golgi network GO:0005802 IDA
    cytosol GO:0005829 IDA
    cytoplasmic vesicle GO:0031410 IDA
 Experiment description of studies that identified C17orf75 in sEVs
1
Experiment ID 217
MISEV standards
EM
Biophysical techniques
TSG101|CD81|CD9|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for C17orf75
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 MESDC2 23184
Two-hybrid Homo sapiens
2 TOMM40 10452
Co-fractionation Homo sapiens
3 SPANXN5  
Affinity Capture-MS Homo sapiens
4 LHFPL4  
Affinity Capture-MS Homo sapiens
5 GPRC5C 55890
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 VDAC3 7419
Co-fractionation Homo sapiens
7 SLC18A1  
Affinity Capture-MS Homo sapiens
8 AIFM1 9131
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 FAS 355
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 EGLN3  
Affinity Capture-MS Homo sapiens
11 TRIM52  
Affinity Capture-MS Homo sapiens
12 DDHD1 80821
Affinity Capture-MS Homo sapiens
13 ATG9A 79065
Proximity Label-MS Homo sapiens
14 NPTN 27020
Affinity Capture-MS Homo sapiens
15 CLEC2D  
Affinity Capture-MS Homo sapiens
16 MGARP  
Affinity Capture-MS Homo sapiens
17 NR3C1 2908
Proximity Label-MS Homo sapiens
18 WDR11 55717
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 SERPINB2 5055
Affinity Capture-MS Homo sapiens
20 TNFAIP6 7130
Affinity Capture-MS Homo sapiens
21 MVK 4598
Affinity Capture-MS Homo sapiens
22 DRG1 4733
Affinity Capture-MS Homo sapiens
23 LRRN4CL 221091
Affinity Capture-MS Homo sapiens
24 CD80 941
Affinity Capture-MS Homo sapiens
25 FIS1 51024
Affinity Capture-MS Homo sapiens
26 LAGE3  
Affinity Capture-MS Homo sapiens
27 FAM91A1 157769
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
28 SV2A 9900
Affinity Capture-MS Homo sapiens
29 OGT 8473
Reconstituted Complex Homo sapiens
30 FGF8  
Affinity Capture-MS Homo sapiens
31 HLA-DRB5 3127
Affinity Capture-MS Homo sapiens
32 FAM174A 345757
Affinity Capture-MS Homo sapiens
33 GLMP 112770
Affinity Capture-MS Homo sapiens
34 COPS3 8533
Two-hybrid Homo sapiens
35 VDAC1 7416
Co-fractionation Homo sapiens
36 STYX  
Affinity Capture-MS Homo sapiens
37 GPNMB 10457
Affinity Capture-MS Homo sapiens
38 DLC1 10395
Affinity Capture-MS Homo sapiens
39 DUPD1  
Two-hybrid Homo sapiens
40 TOMM5  
Co-fractionation Homo sapiens
41 HUWE1 10075
Affinity Capture-MS Homo sapiens
42 DKKL1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which C17orf75 is involved
No pathways found





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