Gene description for FLG2
Gene name filaggrin family member 2
Gene symbol FLG2
Other names/aliases IFPS
Species Homo sapiens
 Database cross references - FLG2
ExoCarta ExoCarta_388698
Entrez Gene 388698
HGNC 33276
MIM 616284
UniProt Q5D862  
 FLG2 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for FLG2
Molecular Function
    structural molecule activity GO:0005198 IEA
    calcium ion binding GO:0005509 IEA
Biological Process
    establishment of skin barrier GO:0061436 IEP
Subcellular Localization
    extracellular exosome GO:0070062 IDA
    cytoplasm GO:0005737 IDA
    nucleus GO:0005634 IDA
 Experiment description of studies that identified FLG2 in exosomes
1
Experiment ID 126
ISEV standards
EV Biophysical techniques
GAPDH
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for FLG2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which FLG2 is involved
No pathways found





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