Gene description for ATG9A
Gene name autophagy related 9A
Gene symbol ATG9A
Other names/aliases APG9L1
MGD3208
mATG9
Species Homo sapiens
 Database cross references - ATG9A
ExoCarta ExoCarta_79065
Entrez Gene 79065
HGNC 22408
MIM 612204
UniProt Q7Z3C6  
 ATG9A identified in exosomes derived from the following tissue/cell type
Platelets 25332113    
Platelets 25332113    
Platelets 25332113    
 Gene ontology annotations for ATG9A
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    late nucleophagy GO:0044805 IBA
    protein localization to pre-autophagosomal structure GO:0034497 IBA
    mitochondrion degradation GO:0000422 IBA
    innate immune response GO:0045087 IEA
    autophagosome assembly GO:0000045 IMP
    piecemeal microautophagy of nucleus GO:0034727 IBA
    protein localization to Golgi apparatus GO:0034067 IEA
    protein transport GO:0015031 IEA
Subcellular Localization
    late endosome GO:0005770 IDA
    late endosome membrane GO:0031902 IEA
    autophagosome GO:0005776 IBA
    autophagosome membrane GO:0000421 IDA
    pre-autophagosomal structure GO:0000407 IDA
    trans-Golgi network GO:0005802 IDA
    recycling endosome GO:0055037 IDA
    integral component of membrane GO:0016021 IEA
    membrane GO:0016020 IDA
    endosome GO:0005768 IDA
    endoplasmic reticulum membrane GO:0005789 IEA
    cytoplasmic vesicle GO:0031410 IEA
 Experiment description of studies that identified ATG9A in exosomes
1
Experiment ID 231
ISEV standards
EV Biophysical techniques
Alix
EV Cytosolic markers
CD63|CD9
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G.
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 232
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G.
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
3
Experiment ID 233
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G.
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ATG9A
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which ATG9A is involved
No pathways found





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