Gene description for LGALS8
Gene name lectin, galactoside-binding, soluble, 8
Gene symbol LGALS8
Other names/aliases Gal-8
Species Homo sapiens
 Database cross references - LGALS8
ExoCarta ExoCarta_3964
Entrez Gene 3964
HGNC 6569
MIM 606099
UniProt O00214  
 LGALS8 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for LGALS8
Molecular Function
    carbohydrate binding GO:0030246 IEA
    protein binding GO:0005515 IPI
Biological Process
    T cell costimulation GO:0031295 IEA
    plasma cell differentiation GO:0002317 IEA
Subcellular Localization
    cytoplasm GO:0005737 IEA
    extracellular exosome GO:0070062 IDA
    membrane GO:0016020 IDA
    extracellular space GO:0005615 TAS
 Experiment description of studies that identified LGALS8 in exosomes
Experiment ID 126
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for LGALS8
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 NDP52  
Two-hybrid Homo sapiens
2 ITGB1 3688
Invivo Homo sapiens
Invitro Homo sapiens
Affinity Capture-MS Homo sapiens
3 ITGA4 3676
Invivo Homo sapiens
Invitro Homo sapiens
4 ITGA3 3675
Invivo Homo sapiens
Invitro Homo sapiens
View the network image/svg+xml
 Pathways in which LGALS8 is involved
No pathways found

Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here