Gene description for STK11
Gene name	serine/threonine kinase 11
Gene symbol	STK11
Other names/aliases	LKB1 PJS hLKB1
Species	Homo sapiens
Database cross references - STK11
ExoCarta	ExoCarta_6794
Entrez Gene	6794
HGNC	11389
MIM	602216
UniProt	Q15831
STK11 identified in exosomes derived from the following tissue/cell type
Urine	19056867

Gene ontology annotations for STK11

Molecular Function     protein kinase activator activity GO:0030295 IDA     magnesium ion binding GO:0000287 IDA     p53 binding GO:0002039 IDA     LRR domain binding GO:0030275 IEA     protein serine/threonine kinase activity GO:0004674 TAS     protein binding GO:0005515 IPI     protein complex binding GO:0032403 IEA     ATP binding GO:0005524 IDA Biological Process     positive regulation of axonogenesis GO:0050772 IEA     positive regulation of gluconeogenesis GO:0045722 IEA     regulation of Wnt signaling pathway GO:0030111 IEA     small molecule metabolic process GO:0044281 TAS     cell cycle arrest GO:0007050 TAS     protein autophosphorylation GO:0046777 IDA     TCR signalosome assembly GO:0036399 IEA     spermatid development GO:0007286 IEA     negative regulation of cell growth GO:0030308 ISS     cellular response to DNA damage stimulus GO:0006974 IMP     canonical Wnt signaling pathway GO:0060070 IEA     response to ionizing radiation GO:0010212 ISS     intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 IDA     protein phosphorylation GO:0006468 IDA     regulation of cell growth GO:0001558 ISS     regulation of protein kinase B signaling GO:0051896 IEA     cellular response to UV-B GO:0071493 IDA     tissue homeostasis GO:0001894 IEA     establishment of cell polarity GO:0030010 ISS     regulation of fatty acid biosynthetic process GO:0042304 TAS     protein heterooligomerization GO:0051291 IEA     response to lipid GO:0033993 IEA     vasculature development GO:0001944 ISS     positive thymic T cell selection GO:0045059 IEA     positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 IMP     Golgi localization GO:0051645 IEA     anoikis GO:0043276 IMP     axonogenesis GO:0007409 IEA     glucose homeostasis GO:0042593 ISS     T cell receptor signaling pathway GO:0050852 IEA     energy reserve metabolic process GO:0006112 TAS     response to glucagon GO:0033762 IEA     insulin receptor signaling pathway GO:0008286 TAS     autophagy GO:0006914 IEA     negative regulation of epithelial cell proliferation involved in prostate gland development GO:0060770 IEA     positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 IEA     negative regulation of cell proliferation GO:0008285 IMP     activation of protein kinase activity GO:0032147 IEA Subcellular Localization     membrane GO:0016020 ISS     extracellular exosome GO:0070062 IDA     TCR signalosome GO:0036398 IEA     cytosol GO:0005829 TAS     nucleus GO:0005634 IDA     cytoplasm GO:0005737 IDA     mitochondrion GO:0005739 IDA