Gene description for TGFBRAP1
Gene name transforming growth factor, beta receptor associated protein 1
Gene symbol TGFBRAP1
Other names/aliases TRAP-1
Species Homo sapiens
 Database cross references - TGFBRAP1
ExoCarta ExoCarta_9392
Entrez Gene 9392
HGNC 16836
MIM 606237
UniProt Q8WUH2  
 TGFBRAP1 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for TGFBRAP1
Molecular Function
    protein binding GO:0005515 IPI
    transforming growth factor beta receptor binding GO:0005160 IDA
    SMAD binding GO:0046332 IDA
Biological Process
    regulation of transcription, DNA-templated GO:0006355 IDA
    transforming growth factor beta receptor signaling pathway GO:0007179 TAS
    vesicle-mediated transport GO:0016192 IEA
    signal transduction GO:0007165 IDA
    intracellular protein transport GO:0006886 IEA
Subcellular Localization
    membrane GO:0016020 IDA
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified TGFBRAP1 in exosomes
Experiment ID 217
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for TGFBRAP1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ACVRL1  
Invivo Homo sapiens
2 SMAD2 4087
Invivo Homo sapiens
3 ALOX5  
Two-hybrid Homo sapiens
4 ACVR1B 91
Invivo Homo sapiens
Affinity Capture-MS Homo sapiens
5 BMPR1A  
Invivo Homo sapiens
Affinity Capture-MS Homo sapiens
6 SMAD4  
Invivo Homo sapiens
Invitro Homo sapiens
Affinity Capture-MS Homo sapiens
7 ACVR2B  
Invivo Homo sapiens
8 TGFBR2 7048
Invivo Homo sapiens
9 TGFBR1  
Invivo Homo sapiens
View the network image/svg+xml
 Pathways in which TGFBRAP1 is involved
No pathways found

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