Gene description for CDIPT
Gene name CDP-diacylglycerol--inositol 3-phosphatidyltransferase
Gene symbol CDIPT
Other names/aliases PIS
PIS1
Species Homo sapiens
 Database cross references - CDIPT
ExoCarta ExoCarta_10423
Entrez Gene 10423
HGNC 1769
MIM 605893
UniProt O14735  
 CDIPT identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for CDIPT
Molecular Function
    alcohol binding GO:0043178 IEA
    CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity GO:0003881 TAS
    carbohydrate binding GO:0030246 IEA
    manganese ion binding GO:0030145 IEA
    protein binding GO:0005515 IPI
    diacylglycerol binding GO:0019992 IEA
Biological Process
    CDP-diacylglycerol metabolic process GO:0046341 IEA
    phosphatidylinositol biosynthetic process GO:0006661 TAS
    small molecule metabolic process GO:0044281 TAS
    glycerophospholipid biosynthetic process GO:0046474 TAS
    phospholipid metabolic process GO:0006644 TAS
Subcellular Localization
    endoplasmic reticulum membrane GO:0005789 TAS
    integral component of membrane GO:0016021 IDA
    plasma membrane GO:0005886 IEA
    membrane GO:0016020 IDA
    Golgi apparatus GO:0005794 IBA
    Golgi membrane GO:0000139 IEA
 Experiment description of studies that identified CDIPT in exosomes
1
Experiment ID 126
ISEV standards
✘ EV Biophysical techniques
✔
GAPDH
EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for CDIPT
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which CDIPT is involved
PathwayEvidenceSource
Synthesis of PI TAS Reactome





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