Gene description for NCK2
Gene name	NCK adaptor protein 2
Gene symbol	NCK2
Other names/aliases	GRB4 NCKbeta
Species	Homo sapiens
Database cross references - NCK2
ExoCarta	ExoCarta_8440
Entrez Gene	8440
HGNC	7665
MIM	604930
UniProt	O43639
NCK2 identified in exosomes derived from the following tissue/cell type
Platelets	25332113
Platelets	25332113
Platelets	25332113

Gene ontology annotations for NCK2

Molecular Function     receptor signaling complex scaffold activity GO:0030159 NAS     protein binding GO:0005515 IPI     SH3/SH2 adaptor activity GO:0005070 NAS     cytoskeletal adaptor activity GO:0008093 NAS Biological Process     negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation GO:1903912 IDA     epidermal growth factor receptor signaling pathway GO:0007173 TAS     positive regulation of T cell proliferation GO:0042102 IMP     positive regulation of signal transduction GO:0009967 NAS     negative regulation of cell proliferation GO:0008285 TAS     negative regulation of peptidyl-serine phosphorylation GO:0033137 IDA     signal complex assembly GO:0007172 NAS     axon guidance GO:0007411 TAS     positive regulation of actin filament polymerization GO:0030838 IMP     lamellipodium assembly GO:0030032 IEA     vascular endothelial growth factor receptor signaling pathway GO:0048010 TAS     cell migration GO:0016477 IEA     ephrin receptor signaling pathway GO:0048013 TAS     regulation of epidermal growth factor-activated receptor activity GO:0007176 TAS     regulation of translation GO:0006417 IEA     positive regulation of transcription from RNA polymerase II promoter GO:0045944 IDA     signal transduction GO:0007165 TAS     T cell activation GO:0042110 NAS     actin filament organization GO:0007015 IEA Subcellular Localization     endoplasmic reticulum GO:0005783 IDA     cytoplasm GO:0005737 NAS     cytosol GO:0005829 TAS     vesicle membrane GO:0012506 IEA