Gene description for PPP1R37
Gene name protein phosphatase 1, regulatory subunit 37
Gene symbol PPP1R37
Other names/aliases LRRC68
Species Homo sapiens
 Database cross references - PPP1R37
ExoCarta ExoCarta_284352
Vesiclepedia VP_284352
Entrez Gene 284352
HGNC 27607
UniProt O75864  
 PPP1R37 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for PPP1R37
Molecular Function
    protein phosphatase inhibitor activity GO:0004864 IEA
    protein binding GO:0005515 IPI
 Experiment description of studies that identified PPP1R37 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for PPP1R37
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HNRNPH1 3187
Affinity Capture-RNA Homo sapiens
2 ZMYND19  
Two-hybrid Homo sapiens
3 RAB35 11021
Proximity Label-MS Homo sapiens
4 RBPMS2  
Two-hybrid Homo sapiens
5 PPP1CB 5500
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
6 EBAG9 9166
Proximity Label-MS Homo sapiens
7 LAMTOR1 55004
Proximity Label-MS Homo sapiens
8 RAB5A 5868
Proximity Label-MS Homo sapiens
9 ATG9A 79065
Proximity Label-MS Homo sapiens
10 PPP1CA 5499
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 S100A2 6273
Affinity Capture-MS Homo sapiens
12 FOXH1  
Two-hybrid Homo sapiens
13 ZNF764 92595
Two-hybrid Homo sapiens
14 HNRNPCL2 440563
Two-hybrid Homo sapiens
15 RAB4A 5867
Proximity Label-MS Homo sapiens
16 CDH1 999
Proximity Label-MS Homo sapiens
17 ZNF837  
Two-hybrid Homo sapiens
18 RAB9A 9367
Proximity Label-MS Homo sapiens
19 GOLGA1  
Proximity Label-MS Homo sapiens
20 DCP1A 55802
Affinity Capture-MS Homo sapiens
21 BEND7 222389
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
22 EPHA2 1969
Proximity Label-MS Homo sapiens
23 RBMY1F  
Two-hybrid Homo sapiens
24 SEH1L 81929
Affinity Capture-MS Homo sapiens
25 KRTAP6-3  
Two-hybrid Homo sapiens
26 STX6 10228
Proximity Label-MS Homo sapiens
27 CALR 811
Co-fractionation Homo sapiens
28 RBMY1J  
Two-hybrid Homo sapiens
29 RAB11A 8766
Proximity Label-MS Homo sapiens
View the network image/svg+xml
 Pathways in which PPP1R37 is involved
No pathways found





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