Gene description for KRT33B
Gene name keratin 33B, type I
Gene symbol KRT33B
Other names/aliases HA3II
Ha-3II
K33B
KRTHA3A
KRTHA3B
hHa3-II
Species Homo sapiens
 Database cross references - KRT33B
ExoCarta ExoCarta_3884
Vesiclepedia VP_3884
Entrez Gene 3884
HGNC 6451
MIM 602762
UniProt Q14525  
 KRT33B identified in exosomes derived from the following tissue/cell type
Urine 21557262    
 Gene ontology annotations for KRT33B
Molecular Function
    structural molecule activity GO:0005198 IEA
    protein binding GO:0005515 IPI
Biological Process
    epithelial cell differentiation GO:0030855 IBA
    hair cycle GO:0042633 IDA
    intermediate filament organization GO:0045109 IBA
Subcellular Localization
    extracellular space GO:0005615 HDA
    cytosol GO:0005829 TAS
    cytoskeleton GO:0005856 IBA
    intermediate filament GO:0005882 IEA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified KRT33B in exosomes
1
Experiment ID 114
MISEV standards
✔
IEM
Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21557262    
Organism Homo sapiens
Experiment description Proteomic identification of exosomal LRG1: A potential urinary biomarker for detecting NSCLC.
Authors "Li Y, Zhang Y, Qiu F, Qiu Z."
Journal name ELEC
Publication year 2011
Sample Urine
Sample name Urine - Lung cancer
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for KRT33B
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 KRT72 140807
Two-hybrid Homo sapiens
2 KRT83  
Two-hybrid Homo sapiens
3 EPPK1 83481
Affinity Capture-MS Homo sapiens
4 KRT85  
Two-hybrid Homo sapiens
5 KRT4 3851
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
6 NUP54 53371
Two-hybrid Homo sapiens
7 GAN 8139
Affinity Capture-MS Homo sapiens
8 ZBTB2 57621
Affinity Capture-MS Homo sapiens
9 KRT3 3850
Two-hybrid Homo sapiens
10 EFNA4  
Affinity Capture-MS Homo sapiens
11 CYSRT1 375791
Two-hybrid Homo sapiens
12 CCDC24  
Two-hybrid Homo sapiens
13 KRT1 3848
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
14 GRB2 2885
Affinity Capture-MS Homo sapiens
15 LMO4  
Two-hybrid Homo sapiens
16 FRS3 10817
Two-hybrid Homo sapiens
17 C1orf216  
Two-hybrid Homo sapiens
18 USP15 9958
Affinity Capture-MS Homo sapiens
19 KRT86  
Two-hybrid Homo sapiens
20 SCNM1  
Two-hybrid Homo sapiens
21 KRT8 3856
Cross-Linking-MS (XL-MS) Homo sapiens
Two-hybrid Homo sapiens
22 AQP1 358
Two-hybrid Homo sapiens
23 FASLG 356
Two-hybrid Homo sapiens
24 EPS15 2060
Affinity Capture-MS Homo sapiens
25 CUL3 8452
Affinity Capture-MS Homo sapiens
26 DES 1674
Two-hybrid Homo sapiens
27 ATG9A 79065
Two-hybrid Homo sapiens
28 ICA1  
Affinity Capture-MS Homo sapiens
29 PLEKHJ1  
Affinity Capture-MS Homo sapiens
30 KRT82 3888
Two-hybrid Homo sapiens
31 MOS 4342
Two-hybrid Homo sapiens
32 KRT71 112802
Two-hybrid Homo sapiens
33 BCL10  
Affinity Capture-MS Homo sapiens
34 DCAF6 55827
Affinity Capture-MS Homo sapiens
35 HOXA1 3198
Two-hybrid Homo sapiens
36 INPP5K 51763
Affinity Capture-MS Homo sapiens
37 KRT6C 286887
Two-hybrid Homo sapiens
38 KLC4 89953
Two-hybrid Homo sapiens
39 HAPLN2  
Two-hybrid Homo sapiens
40 ARFIP1 27236
Two-hybrid Homo sapiens
41 RTP5  
Two-hybrid Homo sapiens
42 CNNM3 26505
Two-hybrid Homo sapiens
43 VPS37C 55048
Two-hybrid Homo sapiens
44 GOLGA6L2  
Two-hybrid Homo sapiens
45 ABI2 10152
Two-hybrid Homo sapiens
46 OTUD4  
Affinity Capture-MS Homo sapiens
47 MB21D2  
Affinity Capture-MS Homo sapiens
48 EFHD1  
Affinity Capture-MS Homo sapiens
49 ZNF639  
Affinity Capture-MS Homo sapiens
50 KRT80 144501
Two-hybrid Homo sapiens
51 UBR1 197131
Affinity Capture-MS Homo sapiens
52 DTNB 1838
Two-hybrid Homo sapiens
53 COX5B 1329
Two-hybrid Homo sapiens
54 KRT75 9119
Two-hybrid Homo sapiens
55 C17orf70  
Affinity Capture-MS Homo sapiens
56 PPP1R18 170954
Two-hybrid Homo sapiens
57 ZER1 10444
Affinity Capture-MS Homo sapiens
58 HGS 9146
Two-hybrid Homo sapiens
59 CCDC101  
Two-hybrid Homo sapiens
60 DUSP21  
Two-hybrid Homo sapiens
61 KRT2 3849
Two-hybrid Homo sapiens
62 SHC3  
Two-hybrid Homo sapiens
63 YWHAG 7532
Affinity Capture-MS Homo sapiens
64 KRT6B 3854
Two-hybrid Homo sapiens
65 OBSL1 23363
Affinity Capture-MS Homo sapiens
66 YBEY  
Affinity Capture-MS Homo sapiens
67 INCA1  
Two-hybrid Homo sapiens
68 RAB26  
Two-hybrid Homo sapiens
69 ZYG11B  
Affinity Capture-MS Homo sapiens
70 Nphp1  
Affinity Capture-MS Mus musculus
71 KRT79 338785
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
72 AIMP2 7965
Two-hybrid Homo sapiens
73 KDM1A 23028
Two-hybrid Homo sapiens
74 FAM103A1  
Two-hybrid Homo sapiens
75 NUPL1 9818
Two-hybrid Homo sapiens
76 KRT78 196374
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which KRT33B is involved
PathwayEvidenceSource
Developmental Biology TAS Reactome
Formation of the cornified envelope TAS Reactome
Keratinization TAS Reactome





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