Gene description for B3GALTL
Gene name beta 1,3-galactosyltransferase-like
Gene symbol B3GALTL
Other names/aliases B3GLCT
B3GTL
B3Glc-T
Gal-T
beta3Glc-T
Species Homo sapiens
 Database cross references - B3GALTL
ExoCarta ExoCarta_145173
Vesiclepedia VP_145173
Entrez Gene 145173
HGNC 20207
MIM 610308
UniProt Q6Y288  
 B3GALTL identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for B3GALTL
Molecular Function
    acetylglucosaminyltransferase activity GO:0008375 IBA
    glycosyltransferase activity GO:0016757 TAS
Biological Process
    skeletal system development GO:0001501 IEA
    fucose metabolic process GO:0006004 IEA
    brain development GO:0007420 IEA
    protein secretion GO:0009306 IEA
    gene expression GO:0010467 IEA
    protein O-linked fucosylation GO:0036066 TAS
    camera-type eye development GO:0043010 IEA
    roof of mouth development GO:0060021 IEA
    limb development GO:0060173 IEA
    cilium assembly GO:0060271 IEA
    cranial skeletal system development GO:1904888 IEA
Subcellular Localization
    endoplasmic reticulum membrane GO:0005789 TAS
 Experiment description of studies that identified B3GALTL in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for B3GALTL
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CCL3  
Affinity Capture-MS Homo sapiens
2 CTSE  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 MARCKS 4082
Co-fractionation Homo sapiens
4 LRRC59 55379
Proximity Label-MS Homo sapiens
5 PDIA4 9601
Proximity Label-MS Homo sapiens
6 TAZ  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 TMEM25  
Affinity Capture-MS Homo sapiens
8 CALR3  
Proximity Label-MS Homo sapiens
9 ALPPL2 251
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 ADAMTS18  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 PDGFRA 5156
Affinity Capture-MS Homo sapiens
12 SMC6  
Affinity Capture-MS Homo sapiens
13 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
14 ADAMTS13 11093
Affinity Capture-MS Homo sapiens
15 ERBB3 2065
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
16 ADAMTSL1 92949
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 THBS2 7058
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
18 CFP  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 IDS  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 C6 729
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
21 EMC2 9694
Affinity Capture-MS Homo sapiens
22 SCGB2A2  
Affinity Capture-MS Homo sapiens
23 PTPRK 5796
Affinity Capture-MS Homo sapiens
24 ADAMTS1 9510
Affinity Capture-MS Homo sapiens
25 PTCH1  
Affinity Capture-MS Homo sapiens
26 AK1 203
Affinity Capture-MS Homo sapiens
27 FGFR1OP  
Affinity Capture-MS Homo sapiens
28 OGT 8473
Reconstituted Complex Homo sapiens
29 PAPLN  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
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