Gene description for ZNF318
Gene name zinc finger protein 318
Gene symbol ZNF318
Other names/aliases HRIHFB2436
TZF
ZFP318
Species Homo sapiens
 Database cross references - ZNF318
ExoCarta ExoCarta_24149
Vesiclepedia VP_24149
Entrez Gene 24149
HGNC 13578
UniProt Q5VUA4  
 ZNF318 identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for ZNF318
Molecular Function
    nucleic acid binding GO:0003676 IEA
    zinc ion binding GO:0008270 IEA
    protein homodimerization activity GO:0042803 ISS
Biological Process
    negative regulation of DNA-templated transcription GO:0045892 IBA
    negative regulation of DNA-templated transcription GO:0045892 ISS
    positive regulation of DNA-templated transcription GO:0045893 IBA
    positive regulation of DNA-templated transcription GO:0045893 ISS
    meiotic cell cycle GO:0051321 IEA
Subcellular Localization
    nucleoplasm GO:0005654 IBA
    nucleoplasm GO:0005654 IDA
    cytosol GO:0005829 IDA
 Experiment description of studies that identified ZNF318 in exosomes
1
Experiment ID 237
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for ZNF318
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 GATA1  
Proximity Label-MS Homo sapiens
2 VPS35 55737
Affinity Capture-MS Homo sapiens
3 UBE2H 7328
Affinity Capture-MS Homo sapiens
4 ISG15 9636
Co-fractionation Homo sapiens
5 HDAC2 3066
Affinity Capture-Western Homo sapiens
6 TRIM66  
Affinity Capture-MS Homo sapiens
7 ACTC1 70
Proximity Label-MS Homo sapiens
8 CELA1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 DHX8 1659
Proximity Label-MS Homo sapiens
10 KIF20A 10112
Affinity Capture-MS Homo sapiens
11 RPL14 9045
Cross-Linking-MS (XL-MS) Homo sapiens
12 RPS2P32  
Affinity Capture-MS Homo sapiens
13 CORO6  
Affinity Capture-MS Homo sapiens
14 PPP1CC 5501
Two-hybrid Homo sapiens
15 PGK1 5230
Cross-Linking-MS (XL-MS) Homo sapiens
16 HSPA2 3306
Affinity Capture-MS Homo sapiens
17 MCM2 4171
Affinity Capture-MS Homo sapiens
18 CARD8  
Affinity Capture-MS Homo sapiens
19 SNRPC 6631
Affinity Capture-MS Homo sapiens
20 BRPF3  
Affinity Capture-MS Homo sapiens
21 GUSBP5  
Affinity Capture-MS Homo sapiens
22 DNAI1  
Affinity Capture-MS Homo sapiens
23 FBL 2091
Affinity Capture-MS Homo sapiens
24 IL17RA 23765
Affinity Capture-MS Homo sapiens
25 MAD2L1 4085
Affinity Capture-MS Homo sapiens
26 TFRC 7037
Cross-Linking-MS (XL-MS) Homo sapiens
27 KIF14 9928
Affinity Capture-MS Homo sapiens
28 METTL10  
Affinity Capture-MS Homo sapiens
29 BAG5 9529
Affinity Capture-MS Homo sapiens
30 CPNE2 221184
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
31 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
32 B4GALT2  
Affinity Capture-MS Homo sapiens
33 GOLGA2 2801
Proximity Label-MS Homo sapiens
34 SLX4  
Affinity Capture-MS Homo sapiens
35 CECR2  
Affinity Capture-MS Homo sapiens
36 ZBTB46  
Affinity Capture-MS Homo sapiens
37 KRT2 3849
Affinity Capture-MS Homo sapiens
38 VCPIP1 80124
Affinity Capture-MS Homo sapiens
39 CEBPA  
Proximity Label-MS Homo sapiens
40 NMNAT2  
Affinity Capture-MS Homo sapiens
41 PHLPP1  
Proximity Label-MS Homo sapiens
42 DISC1 27185
Affinity Capture-MS Homo sapiens
43 BAG1 573
Affinity Capture-MS Homo sapiens
44 BAG2 9532
Affinity Capture-MS Homo sapiens
45 SIRT7  
Affinity Capture-MS Homo sapiens
46 NCAPH2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
47 SNRPB 6628
Affinity Capture-MS Homo sapiens
48 CRYAA 1409
Affinity Capture-MS Homo sapiens
49 RPL36A 6173
Cross-Linking-MS (XL-MS) Homo sapiens
50 PTEN 5728
Affinity Capture-MS Homo sapiens
51 NUP43 348995
Proximity Label-MS Homo sapiens
52 AP1G2 8906
Affinity Capture-MS Homo sapiens
53 SF3A1 10291
Affinity Capture-MS Homo sapiens
54 SGTB  
Affinity Capture-MS Homo sapiens
55 ABTB2 25841
Affinity Capture-MS Homo sapiens
56 RARRES1 5918
Affinity Capture-MS Homo sapiens
57 RPA3 6119
Proximity Label-MS Homo sapiens
58 HSPA1A 3303
Affinity Capture-MS Homo sapiens
59 P4HA3 283208
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
60 MIER2  
Affinity Capture-MS Homo sapiens
61 MDM2  
Affinity Capture-MS Homo sapiens
62 BAG4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
63 CCDC8  
Affinity Capture-MS Homo sapiens
64 SMUG1  
Affinity Capture-MS Homo sapiens
65 CCBL1 883
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
66 RNF43  
Proximity Label-MS Homo sapiens
67 ASB3 51130
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
68 SIRT6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
69 CPSF6 11052
Affinity Capture-MS Homo sapiens
70 LIPH 200879
Affinity Capture-MS Homo sapiens
71 PDIA4 9601
Cross-Linking-MS (XL-MS) Homo sapiens
72 APOBEC3D  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
73 TRIM52  
Affinity Capture-MS Homo sapiens
74 Cep135  
Affinity Capture-MS Mus musculus
75 SNRPA 6626
Affinity Capture-MS Homo sapiens
76 PNMA1 9240
Affinity Capture-MS Homo sapiens
77 DHX40  
Proximity Label-MS Homo sapiens
78 C6orf141  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
79 NUP50 10762
Proximity Label-MS Homo sapiens
80 TRIM37  
Proximity Label-MS Homo sapiens
81 KRT38 8687
Affinity Capture-MS Homo sapiens
82 PRPF39 55015
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
83 CDC16 8881
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
84 AP4M1 9179
Affinity Capture-MS Homo sapiens
85 HSD17B7P2  
Affinity Capture-MS Homo sapiens
86 AR 367
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
87 CCDC96  
Affinity Capture-MS Homo sapiens
88 CCT8L2  
Affinity Capture-MS Homo sapiens
89 SP7  
Proximity Label-MS Homo sapiens
90 FAM160B2 64760
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which ZNF318 is involved
No pathways found





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