Gene ontology annotations for MINPP1
Molecular Function
acid phosphatase activity
GO:0003993
IBA
inositol-hexakisphosphate phosphatase activity
GO:0004446
IDA
inositol-hexakisphosphate phosphatase activity
GO:0004446
IMP
protein binding
GO:0005515
IPI
4-phytase activity
GO:0008707
IEA
3-phytase activity
GO:0016158
IEA
inositol bisphosphate phosphatase activity
GO:0016312
IDA
inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity
GO:0030351
IDA
inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity
GO:0030351
TAS
inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity
GO:0030352
IDA
bisphosphoglycerate 3-phosphatase activity
GO:0034417
IDA
inositol trisphosphate phosphatase activity
GO:0046030
IDA
inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity
GO:0051717
IDA
inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity
GO:0051717
TAS
inositol phosphate phosphatase activity
GO:0052745
IBA
inositol phosphate phosphatase activity
GO:0052745
NAS
inositol hexakisphosphate 2-phosphatase activity
GO:0052826
TAS
inositol pentakisphosphate phosphatase activity
GO:0052827
IMP
Biological Process
ossification
GO:0001503
NAS
intracellular monoatomic cation homeostasis
GO:0030003
IMP
bone mineralization
GO:0030282
NAS
inositol phosphate metabolic process
GO:0043647
TAS
Subcellular Localization
extracellular space
GO:0005615
IMP
endoplasmic reticulum lumen
GO:0005788
ISS
endoplasmic reticulum lumen
GO:0005788
TAS
plasma membrane
GO:0005886
ISS
extracellular exosome
GO:0070062
HDA
Experiment description of studies that identified MINPP1 in exosomes
1
Experiment ID
489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 6
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
2
Experiment ID
490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 7
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
3
Experiment ID
491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 8
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
4
Experiment ID
492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 9
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
Protein-protein interactions for MINPP1
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
GSTP1
2950
Co-fractionation
Homo sapiens
2
HNRNPLL
92906
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
3
PMPCA
23203
Co-fractionation
Homo sapiens
4
PMPCB
9512
Co-fractionation
Homo sapiens
5
PPP1CB
5500
Affinity Capture-MS
Homo sapiens
6
TSFM
10102
Co-fractionation
Homo sapiens
7
SCGB2A1
4246
Affinity Capture-MS
Homo sapiens
8
CALR3
Proximity Label-MS
Homo sapiens
9
PDIA4
9601
Proximity Label-MS
Homo sapiens
10
LRRC59
55379
Proximity Label-MS
Homo sapiens
11
UBQLN2
29978
Two-hybrid
Homo sapiens
12
CD70
970
Affinity Capture-MS
Homo sapiens
13
PDGFRA
5156
Affinity Capture-MS
Homo sapiens
14
CD274
29126
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
15
EFNA5
Affinity Capture-MS
Homo sapiens
16
PRG2
Affinity Capture-MS
Homo sapiens
17
PPP5C
5536
Co-fractionation
Homo sapiens
18
SOX4
Two-hybrid
Homo sapiens
19
EFNA4
Affinity Capture-MS
Homo sapiens
20
TMCO6
Affinity Capture-MS
Homo sapiens
21
CYP1A1
Affinity Capture-MS
Homo sapiens
22
FBXO6
26270
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
23
UBE2V1
7335
Affinity Capture-MS
Homo sapiens
24
SPINK4
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
25
MGAT2
4247
Affinity Capture-MS
Homo sapiens
26
GDAP1
54332
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
27
GRHPR
9380
Co-fractionation
Homo sapiens
28
CLEC12B
Affinity Capture-MS
Homo sapiens
29
C1orf87
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
30
RPA3
6119
Proximity Label-MS
Homo sapiens
31
FBXO2
26232
Affinity Capture-MS
Homo sapiens
32
OGT
8473
Reconstituted Complex
Homo sapiens
33
TPI1
7167
Co-fractionation
Homo sapiens
34
IL27RA
9466
Affinity Capture-MS
Homo sapiens
35
GIMAP1
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
36
FOXRED1
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
37
LYPD6
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
38
NAT14
57106
Affinity Capture-MS
Homo sapiens
39
VWA1
64856
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
40
UBE2V2
7336
Affinity Capture-MS
Homo sapiens
41
SEC61B
10952
Proximity Label-MS
Homo sapiens
42
MRS2
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
View the network
image/svg+xml
Pathways in which MINPP1 is involved