Gene description for KDELC1
Gene name KDEL (Lys-Asp-Glu-Leu) containing 1
Gene symbol KDELC1
Other names/aliases EP58
KDEL1
Species Homo sapiens
 Database cross references - KDELC1
ExoCarta ExoCarta_79070
Vesiclepedia VP_79070
Entrez Gene 79070
HGNC 19350
MIM 611613
UniProt Q6UW63  
 KDELC1 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for KDELC1
Molecular Function
    UDP-glucosyltransferase activity GO:0035251 IDA
    UDP-xylosyltransferase activity GO:0035252 IDA
    glucosyltransferase activity GO:0046527 IBA
    EGF-domain serine glucosyltransferase activity GO:0140561 IEA
    EGF-domain serine xylosyltransferase activity GO:0140562 IEA
Biological Process
    protein O-linked glycosylation via serine GO:0018242 IDA
    protein O-linked glycosylation via serine GO:0018242 IMP
Subcellular Localization
    nucleoplasm GO:0005654 IDA
    endoplasmic reticulum lumen GO:0005788 ISS
    cytosol GO:0005829 IDA
    endomembrane system GO:0012505 IBA
 Experiment description of studies that identified KDELC1 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for KDELC1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 LY86  
Affinity Capture-MS Homo sapiens
2 ATG16L1 55054
Affinity Capture-MS Homo sapiens
3 LY6H  
Affinity Capture-MS Homo sapiens
4 ARSA 410
Affinity Capture-MS Homo sapiens
5 GPIHBP1  
Affinity Capture-MS Homo sapiens
6 TRIM65 201292
Affinity Capture-MS Homo sapiens
7 ELSPBP1  
Affinity Capture-MS Homo sapiens
8 TMEM106A  
Affinity Capture-MS Homo sapiens
9 NAAA  
Affinity Capture-MS Homo sapiens
10 KLK15  
Affinity Capture-MS Homo sapiens
11 C1QTNF9B  
Affinity Capture-MS Homo sapiens
12 CUL2 8453
Affinity Capture-MS Homo sapiens
13 RPA2 6118
Proximity Label-MS Homo sapiens
14 LCN6  
Affinity Capture-MS Homo sapiens
15 LRRC59 55379
Proximity Label-MS Homo sapiens
16 PDIA4 9601
Proximity Label-MS Homo sapiens
17 TAZ  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
18 CALU 813
Proximity Label-MS Homo sapiens
19 CALR3  
Proximity Label-MS Homo sapiens
20 GGH 8836
Affinity Capture-MS Homo sapiens
21 PTCH1  
Affinity Capture-MS Homo sapiens
22 B3GNT3 10331
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
23 PDGFRA 5156
Affinity Capture-MS Homo sapiens
24 PRG2  
Affinity Capture-MS Homo sapiens
25 MFAP4 4239
Affinity Capture-MS Homo sapiens
26 CUL3 8452
Affinity Capture-MS Homo sapiens
27 ITGB8 3696
Affinity Capture-MS Homo sapiens
28 LOXL3 84695
Affinity Capture-MS Homo sapiens
29 CBLN4  
Affinity Capture-MS Homo sapiens
30 GAA 2548
Affinity Capture-MS Homo sapiens
31 P3H1 64175
Affinity Capture-MS Homo sapiens
32 IL5RA  
Affinity Capture-MS Homo sapiens
33 GCNT2 2651
Affinity Capture-MS Homo sapiens
34 LYZL6  
Affinity Capture-MS Homo sapiens
35 SPSB3  
Affinity Capture-MS Homo sapiens
36 MSTN  
Affinity Capture-MS Homo sapiens
37 CELA3A  
Affinity Capture-MS Homo sapiens
38 LYZL1  
Affinity Capture-MS Homo sapiens
39 TMEM25  
Affinity Capture-MS Homo sapiens
40 Ankrd28  
Affinity Capture-MS Mus musculus
41 BRICD5  
Affinity Capture-MS Homo sapiens
42 EFNA2  
Affinity Capture-MS Homo sapiens
43 HSPA5 3309
Affinity Capture-MS Homo sapiens
44 SCGB2A2  
Affinity Capture-MS Homo sapiens
45 C1orf54  
Affinity Capture-MS Homo sapiens
46 FCN3 8547
Affinity Capture-MS Homo sapiens
47 DNAJB9 4189
Affinity Capture-MS Homo sapiens
48 GML  
Affinity Capture-MS Homo sapiens
49 ENPP7 339221
Affinity Capture-MS Homo sapiens
50 DNASE1L1 1774
Affinity Capture-MS Homo sapiens
51 EDN3  
Affinity Capture-MS Homo sapiens
52 CALCOCO2  
Affinity Capture-MS Homo sapiens
53 BMP1 649
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
54 DPEP2  
Affinity Capture-MS Homo sapiens
55 TRAV20  
Affinity Capture-MS Homo sapiens
56 RPA3 6119
Proximity Label-MS Homo sapiens
57 LYPD4  
Affinity Capture-MS Homo sapiens
58 SEC61B 10952
Proximity Label-MS Homo sapiens
59 PRG3  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which KDELC1 is involved
No pathways found





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