Experiment description of studies that identified PDCD2L in exosomes

1 Experiment ID 363 MISEV standards ✘ Biophysical techniques ✔ TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1 Enriched markers ✔ DCLK1 Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 33991177     Organism Homo sapiens Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M." Journal name Proteomics Publication year 2021 Sample Gastric cancer cells Sample name MKN1 - 100K pellet Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

2 Experiment ID 364 MISEV standards ✘ Biophysical techniques ✔ TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1 Enriched markers ✔ DCLK1 Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 33991177     Organism Homo sapiens Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M." Journal name Proteomics Publication year 2021 Sample Gastric cancer cells Sample name MKN1 - 100K pellet Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

3 Experiment ID 365 MISEV standards ✘ Biophysical techniques ✔ TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1 Enriched markers ✔ DCLK1 Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 33991177     Organism Homo sapiens Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M." Journal name Proteomics Publication year 2021 Sample Gastric cancer cells Sample name MKN1 - 100K pellet Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

4 Experiment ID 211 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|EpCAM|TFRC Enriched markers ✔ cytochrome c|GOLGA2 Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 23333927     Organism Homo sapiens Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes. Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K." Journal name J Proteomics Publication year 2013 Sample Ovarian cancer cells Sample name IGROV1 Isolation/purification methods Differential centrifugation Ultracentrifugation Sucrose density gradient Flotation density 1.09-1.15 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry

5 Experiment ID 212 MISEV standards ✔ CEM Biophysical techniques ✔ TSG101|Alix|EpCAM|TFRC Enriched markers ✔ Cytochrome C|GOLGA2 Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 23333927     Organism Homo sapiens Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes. Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K." Journal name J Proteomics Publication year 2013 Sample Ovarian cancer cells Sample name OVCAR-3 Isolation/purification methods Differential centrifugation Ultracentrifugation Sucrose density gradient Flotation density 1.09-1.15 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry

Protein-protein interactions for PDCD2L

Protein Interactor ExoCarta ID Identification method PubMed Species 1 XXYLT1 152002 Affinity Capture-MS Homo sapiens 2 ZRANB1 54764 Affinity Capture-MS Homo sapiens 3 EIF1AD 84285 Affinity Capture-MS Homo sapiens 4 UBE2H 7328 Affinity Capture-MS Homo sapiens 5 PRMT3 10196 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 6 SNX27 81609 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 7 PLEKHA4 57664 Affinity Capture-MS Homo sapiens 8 ARHGAP22 58504 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 9 FEM1A   Affinity Capture-MS Homo sapiens 10 CUL3 8452 Affinity Capture-MS Homo sapiens 11 RPS2 6187 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 12 GPR156   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 13 OTUD1 220213 Affinity Capture-MS Homo sapiens 14 XPO1 7514 Affinity Capture-MS Homo sapiens 15 SLX4IP   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 16 CD6 923 Affinity Capture-MS Homo sapiens 17 EIF5A2 56648 Affinity Capture-MS Homo sapiens 18 PRPH 5630 Proximity Label-MS Homo sapiens 19 NCKIPSD 51517 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 20 PAGE1   Affinity Capture-MS Homo sapiens 21 CCDC102B   Affinity Capture-MS Homo sapiens 22 PCBP3 54039 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 23 RNF7   Affinity Capture-MS Homo sapiens 24 CCDC85A   Affinity Capture-MS Homo sapiens 25 NEK7 140609 Affinity Capture-MS Homo sapiens 26 AHCYL2 23382 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 27 RPA3 6119 Proximity Label-MS Homo sapiens 28 C16orf72 29035 Affinity Capture-MS Homo sapiens 29 OGT 8473 Reconstituted Complex Homo sapiens 30 ZMYND8 23613 Affinity Capture-MS Homo sapiens 31 COPS6 10980 Affinity Capture-MS Homo sapiens 32 SPAG9 9043 Affinity Capture-MS Homo sapiens 33 KLHL22 84861 Affinity Capture-MS Homo sapiens 34 NAP1L5   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 35 KLHL10   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 36 KANK4   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 37 COA7   Affinity Capture-MS Homo sapiens 38 GPBP1L1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 39 ITGB1BP2   Affinity Capture-Luminescence Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 40 BRPF3   Affinity Capture-MS Homo sapiens 41 BMX   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 42 FBXO38 81545 Proximity Label-MS Homo sapiens 43 SRP14 6727 Affinity Capture-MS Homo sapiens 44 GRAMD1B   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 45 TULP3 7289 Affinity Capture-MS Homo sapiens 46 ARIH1 25820 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 47 SHC1 6464 Affinity Capture-MS Homo sapiens View the network

Pathways in which PDCD2L is involved

No pathways found