Gene description for SLC9A3R2
Gene name
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
Gene symbol
SLC9A3R2
Other names/aliases
E3KARP NHE3RF2 NHERF-2 NHERF2 OCTS2 SIP-1 SIP1 TKA-1
Species
Homo sapiens
Database cross references - SLC9A3R2
ExoCarta
ExoCarta_9351
Entrez Gene
9351
HGNC
11076
MIM
606553
UniProt
Q15599
SLC9A3R2 identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells
23333927
Ovarian cancer cells
23333927
Urine
19056867
Gene ontology annotations for SLC9A3R2
Experiment description of studies that identified SLC9A3R2 in exosomes
1
Experiment ID
211
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix
EV Cytosolic markers
✔
EpCAM|TFRC
EV Membrane markers
✔
cytochrome c|GOLGA2
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
IGROV1
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
2
Experiment ID
212
ISEV standards
✔
CEM
EV Biophysical techniques
✔
TSG101|Alix
EV Cytosolic markers
✔
EpCAM|TFRC
EV Membrane markers
✔
Cytochrome C|GOLGA2
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
OVCAR-3
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
3
Experiment ID
63
ISEV standards
✘
EV Biophysical techniques
✘
EV Cytosolic markers
✔
AQP2
EV Membrane markers
✘
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
19056867
Organism
Homo sapiens
Experiment description
Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors
Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name
JASN
Publication year
2009
Sample
Urine
Sample name
Urine - Normal
Isolation/purification methods
Differential centrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry [LTQ] Western blotting
Protein-protein interactions for SLC9A3R2
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
ACTN4
81
Affinity Capture-Western
Homo sapiens
Reconstituted Complex
Homo sapiens
2
PIK3CA
5290
Reconstituted Complex
Homo sapiens
3
EZR
7430
Reconstituted Complex
Homo sapiens
Affinity Capture-Western
Homo sapiens
4
ADRB2
Invitro
Homo sapiens
5
PTHR1
Invivo
Homo sapiens
6
KCNJ1
Two-hybrid
Homo sapiens
Reconstituted Complex
Homo sapiens
7
CFTR
Invivo
Homo sapiens
Invivo
Homo sapiens
Invitro
Homo sapiens
Invitro
Homo sapiens
8
PDZK1
5174
Two-hybrid
Homo sapiens
9
PODXL
5420
Affinity Capture-Western
Homo sapiens
Affinity Capture-Western
Homo sapiens
Reconstituted Complex
Homo sapiens
Reconstituted Complex
Homo sapiens
Affinity Capture-Western
Homo sapiens
10
SGK1
Invivo
Homo sapiens
Invitro
Homo sapiens
Reconstituted Complex
Homo sapiens
Biochemical Activity
Homo sapiens
Reconstituted Complex
Homo sapiens
11
WWTR1
25937
Affinity Capture-Western
Homo sapiens
12
ADORA2B
Affinity Capture-Western
Homo sapiens
13
Rdx
19684
Co-crystal Structure
Mus musculus
14
SLC9A3
6550
Reconstituted Complex
Homo sapiens
15
P2RY1
Invitro
Homo sapiens
16
PDPK1
Affinity Capture-Western
Homo sapiens
Affinity Capture-Western
Homo sapiens
17
SGKL
Invitro
Homo sapiens
18
PLCB3
5331
Invivo
Homo sapiens
19
SLC26A3
Reconstituted Complex
Homo sapiens
View the network
image/svg+xml
Pathways in which SLC9A3R2 is involved
No pathways found