Gene description for KRT8
Gene name keratin 8, type II
Gene symbol KRT8
Other names/aliases CARD2
CK-8
CK8
CYK8
K2C8
K8
KO
Species Homo sapiens
 Database cross references - KRT8
ExoCarta ExoCarta_3856
Vesiclepedia VP_3856
Entrez Gene 3856
HGNC 6446
MIM 148060
UniProt P05787  
 KRT8 identified in sEVs derived from the following tissue/cell type
Bladder cancer cells 20224111    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 17956143    
Colorectal cancer cells 19837982    
Colorectal cancer cells 34887515    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Hepatocellular carcinoma cells 26054723    
Hepatocellular carcinoma cells 26054723    
Hepatocellular carcinoma cells 26054723    
Hepatocytes 26054723    
Mesenchymal stem cells Unpublished / Not applicable
Mesenchymal stem cells 36408942    
Nasopharyngeal carcinoma cells 25857718    
Nasopharyngeal carcinoma cells 25857718    
Nasopharyngeal carcinoma cells 25857718    
Neuroblastoma cells 25944692    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Prostate cancer cells 22723089    
Prostate cancer cells 25844599    
Prostate cancer cells 25844599    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
Saliva 19199708    
 Gene ontology annotations for KRT8
Molecular Function
    protein binding GO:0005515 IPI
    protein-containing complex binding GO:0044877 IEA
    scaffold protein binding GO:0097110 IPI
Biological Process
    tumor necrosis factor-mediated signaling pathway GO:0033209 IEA
    sarcomere organization GO:0045214 IEA
    response to hydrostatic pressure GO:0051599 IEA
    response to other organism GO:0051707 IEA
    cell differentiation involved in embryonic placenta development GO:0060706 IEA
    extrinsic apoptotic signaling pathway GO:0097191 IEA
    hepatocyte apoptotic process GO:0097284 IEA
Subcellular Localization
    nucleus GO:0005634 HDA
    nucleoplasm GO:0005654 IEA
    cytoplasm GO:0005737 IDA
    cytosol GO:0005829 TAS
    intermediate filament GO:0005882 IDA
    cell-cell junction GO:0005911 IEA
    dystrophin-associated glycoprotein complex GO:0016010 IEA
    apicolateral plasma membrane GO:0016327 IEA
    nuclear matrix GO:0016363 IEA
    Z disc GO:0030018 IEA
    sarcolemma GO:0042383 IEA
    costamere GO:0043034 IEA
    keratin filament GO:0045095 IPI
    intermediate filament cytoskeleton GO:0045111 IDA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified KRT8 in sEVs
1
Experiment ID 76
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|GAPDH|HSP90|CD81|CD9|CD63|LAMP1|MHCI
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20224111    
Organism Homo sapiens
Experiment description Proteomics analysis of bladder cancer exosomes.
Authors "Welton JL, Khanna S, Giles PJ, Brennan P, Brewis IA, Staffurth J, Mason MD, Clayton A."
Journal name MCP
Publication year 2010
Sample Bladder cancer cells
Sample name HT1376
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.10-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF/TOF]
Western blotting
FACS
2
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
7
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
8
Experiment ID 20
MISEV standards
✔
EM
Biophysical techniques
✔
HSP90|CD63|CD81|LAMP1
Enriched markers
✔
GOLGA2|cytochrome c
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17956143    
Organism Homo sapiens
Experiment description Proteomic analysis of microvesicles derived from human colorectal cancer cells.
Authors "Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS"
Journal name JPR
Publication year 2007
Sample Colorectal cancer cells
Sample name HT29
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Diafiltration
Flotation density 1.16 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
9
Experiment ID 21
MISEV standards
✔
EM|IEM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD63
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry   
PubMed ID 19837982    
Organism Homo sapiens
Experiment description Proteomic and bioinformatic analysis of immunoaffinity-purified exosomes derived from the human colon tumor cell line LIM1215.
Authors "Suresh Mathivanan, Justin W.E. Lim, Bow J. Tauro, Hong Ji, Robert L. Moritz and Richard J. Simpson"
Journal name MCP
Publication year 2009
Sample Colorectal cancer cells
Sample name LIM1215
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.10-1.12 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [Orbitrap]
Western blotting
10
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
11
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
13
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
14
Experiment ID 234
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-C3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
15
Experiment ID 235
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
16
Experiment ID 236
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
17
Experiment ID 237
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
18
Experiment ID 126
MISEV standards
✘ Biophysical techniques
✔
GAPDH
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
19
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
20
Experiment ID 219
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|CD9
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25857718    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from nasopharyngeal carcinoma cell identifies intercellular transfer of angiogenic proteins
Authors "Chan YK, Zhang H, Liu P, Tsao GS, Li Lung M, Mak NK, Ngok-Shun Wong R, Ying-Kit Yue P"
Journal name Int J Cancer
Publication year 2015
Sample Nasopharyngeal carcinoma cells
Sample name C666-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.17-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
21
Experiment ID 220
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|CD9
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25857718    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from nasopharyngeal carcinoma cell identifies intercellular transfer of angiogenic proteins
Authors "Chan YK, Zhang H, Liu P, Tsao GS, Li Lung M, Mak NK, Ngok-Shun Wong R, Ying-Kit Yue P"
Journal name Int J Cancer
Publication year 2015
Sample Nasopharyngeal carcinoma cells
Sample name NP69
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.17-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
22
Experiment ID 221
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|CD9
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25857718    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from nasopharyngeal carcinoma cell identifies intercellular transfer of angiogenic proteins
Authors "Chan YK, Zhang H, Liu P, Tsao GS, Li Lung M, Mak NK, Ngok-Shun Wong R, Ying-Kit Yue P"
Journal name Int J Cancer
Publication year 2015
Sample Nasopharyngeal carcinoma cells
Sample name NP460
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.17-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
23
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
24
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
25
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
26
Experiment ID 139
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name DU145 - Rep 3
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
27
Experiment ID 275
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel sensitive
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.12-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry/Flow cytometry/Western blotting
28
Experiment ID 274
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel resistant
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Flow cytometry
Western blotting
29
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
30
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
31
Experiment ID 66
MISEV standards
✔
IEM
Biophysical techniques
✔
TSG101|Alix|CD63|CD81
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19199708    
Organism Homo sapiens
Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors "Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR"
Journal name JPR
Publication year 2009
Sample Saliva
Sample name Saliva
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for KRT8
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UBE2H 7328
Affinity Capture-MS Homo sapiens
2 INSIG1  
Affinity Capture-MS Homo sapiens
3 KIF16B 55614
Proximity Label-MS Homo sapiens
4 ARHGAP21 57584
Proximity Label-MS Homo sapiens
5 DLG5 9231
Proximity Label-MS Homo sapiens
6 NUF2  
Proximity Label-MS Homo sapiens
7 CCSER2 54462
Proximity Label-MS Homo sapiens
8 RPGRIP1L 23322
Proximity Label-MS Homo sapiens
9 RABEP1 9135
Proximity Label-MS Homo sapiens
10 KRT1 3848
Proximity Label-MS Homo sapiens
11 CEP89 84902
Proximity Label-MS Homo sapiens
12 DOCK4 9732
Proximity Label-MS Homo sapiens
13 TBC1D4  
Proximity Label-MS Homo sapiens
14 ALMS1  
Proximity Label-MS Homo sapiens
15 NUP188 23511
Proximity Label-MS Homo sapiens
16 TRIP13 9319
Proximity Label-MS Homo sapiens
17 RPAP2  
Proximity Label-MS Homo sapiens
18 KRT17 3872
Two-hybrid Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
19 BTF3 689
Affinity Capture-MS Homo sapiens
20 CRK 1398
Affinity Capture-MS Homo sapiens
21 NUP62 23636
Proximity Label-MS Homo sapiens
22 FBXO25  
Biochemical Activity Homo sapiens
23 APC  
Proximity Label-MS Homo sapiens
24 GFAP 2670
Proximity Label-MS Homo sapiens
25 DTNA  
Proximity Label-MS Homo sapiens
26 BYSL 705
Two-hybrid Homo sapiens
27 GRIPAP1 56850
Proximity Label-MS Homo sapiens
28 KPNA2 3838
Two-hybrid Homo sapiens
29 CAMSAP2  
Proximity Label-MS Homo sapiens
30 KIF7 374654
Proximity Label-MS Homo sapiens
31 CLUH 23277
Proximity Label-MS Homo sapiens
32 FKBP4 2288
Proximity Label-MS Homo sapiens
33 LTN1 26046
Proximity Label-MS Homo sapiens
34 RNF208  
Affinity Capture-MS Homo sapiens
35 ANKRD28 23243
Proximity Label-MS Homo sapiens
36 SOX2  
Affinity Capture-MS Homo sapiens
37 CEP97 79598
Proximity Label-MS Homo sapiens
38 TRIM54  
Two-hybrid Homo sapiens
39 TNIP1 10318
Proximity Label-MS Homo sapiens
40 FGFR3 2261
Two-hybrid Homo sapiens
41 CSPP1  
Proximity Label-MS Homo sapiens
42 APEX1 328
Affinity Capture-MS Homo sapiens
43 KIAA1429 25962
Affinity Capture-MS Homo sapiens
44 WDR62  
Proximity Label-MS Homo sapiens
45 TNRC6C  
Proximity Label-MS Homo sapiens
46 PPL 5493
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
47 CFAP45 25790
Cross-Linking-MS (XL-MS) Homo sapiens
48 WDR76  
Affinity Capture-MS Homo sapiens
49 PCNT  
Proximity Label-MS Homo sapiens
50 TNRC6A 27327
Proximity Label-MS Homo sapiens
51 TBC1D31  
Proximity Label-MS Homo sapiens
52 IFT74 80173
Proximity Label-MS Homo sapiens
53 HELZ 9931
Proximity Label-MS Homo sapiens
54 GOLGA3 2802
Proximity Label-MS Homo sapiens
55 NAV1 89796
Proximity Label-MS Homo sapiens
56 TBC1D2B 23102
Proximity Label-MS Homo sapiens
57 INA 9118
Proximity Label-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
58 CCDC14  
Proximity Label-MS Homo sapiens
59 DIAPH3 81624
Proximity Label-MS Homo sapiens
60 CCDC138  
Proximity Label-MS Homo sapiens
61 KRT40  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
62 ERC1 23085
Proximity Label-MS Homo sapiens
63 KRT10 3858
Cross-Linking-MS (XL-MS) Homo sapiens
64 NUP93 9688
Proximity Label-MS Homo sapiens
65 MAPK14 1432
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
66 OBSL1 23363
Affinity Capture-MS Homo sapiens
67 NBR1 4077
Proximity Label-MS Homo sapiens
68 KRT31 3881
Two-hybrid Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
69 TRIP11 9321
Proximity Label-MS Homo sapiens
70 SF3B3 23450
Proximity Label-MS Homo sapiens
71 CEP162  
Proximity Label-MS Homo sapiens
72 ITGA4 3676
Affinity Capture-MS Homo sapiens
73 EED  
Affinity Capture-MS Homo sapiens
74 CCDC18  
Proximity Label-MS Homo sapiens
75 VCAM1 7412
Affinity Capture-MS Homo sapiens
76 CEP57  
Two-hybrid Homo sapiens
77 PPP6R1 22870
Proximity Label-MS Homo sapiens
78 NUP88 4927
Proximity Label-MS Homo sapiens
79 MECP2 4204
Affinity Capture-MS Homo sapiens
80 TTLL5  
Proximity Label-MS Homo sapiens
81 ARIH2 10425
Affinity Capture-MS Homo sapiens
82 WBP2 23558
Reconstituted Complex Homo sapiens
83 HSPA2 3306
Affinity Capture-MS Homo sapiens
84 FAF2 23197
Affinity Capture-MS Homo sapiens
85 SYNM 23336
Proximity Label-MS Homo sapiens
86 N4BP2  
Proximity Label-MS Homo sapiens
87 PDZRN3 23024
Proximity Label-MS Homo sapiens
88 VPS53 55275
Proximity Label-MS Homo sapiens
89 TFIP11  
Two-hybrid Homo sapiens
90 KIF14 9928
Proximity Label-MS Homo sapiens
91 HSPA8 3312
Affinity Capture-MS Homo sapiens
92 INSIG2  
Affinity Capture-MS Homo sapiens
93 MAPK1 5594
Biochemical Activity Homo sapiens
94 PATL1 219988
Proximity Label-MS Homo sapiens
95 FARSA 2193
Proximity Label-MS Homo sapiens
96 KRT12 3859
Cross-Linking-MS (XL-MS) Homo sapiens
97 STAM2 10254
Co-fractionation Homo sapiens
98 CEP350 9857
Proximity Label-MS Homo sapiens
99 KRT34  
Two-hybrid Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
100 DES 1674
Cross-Linking-MS (XL-MS) Homo sapiens
101 FAM193A  
Proximity Label-MS Homo sapiens
102 CEP55 55165
Proximity Label-MS Homo sapiens
103 TBK1 29110
Proximity Label-MS Homo sapiens
104 PRPH 5630
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
105 PIBF1  
Proximity Label-MS Homo sapiens
106 PPP6R2 9701
Proximity Label-MS Homo sapiens
107 CEP192 55125
Proximity Label-MS Homo sapiens
108 SIPA1L1 26037
Proximity Label-MS Homo sapiens
109 CDR2L  
Proximity Label-MS Homo sapiens
110 KLC4 89953
Proximity Label-MS Homo sapiens
111 KRT74 121391
Cross-Linking-MS (XL-MS) Homo sapiens
112 MAPRE1 22919
Proximity Label-MS Homo sapiens
113 NUP107 57122
Proximity Label-MS Homo sapiens
114 ATF2  
Affinity Capture-MS Homo sapiens
115 OFD1 8481
Proximity Label-MS Homo sapiens
116 XPOT 11260
Proximity Label-MS Homo sapiens
117 PPEF2 5470
Affinity Capture-MS Homo sapiens
118 IPO8 10526
Proximity Label-MS Homo sapiens
119 UBASH3B 84959
Affinity Capture-MS Homo sapiens
120 CEP152  
Proximity Label-MS Homo sapiens
121 CDH1 999
Affinity Capture-MS Homo sapiens
122 C2orf44  
Proximity Label-MS Homo sapiens
123 CNOT1 23019
Proximity Label-MS Homo sapiens
124 GIT2 9815
Proximity Label-MS Homo sapiens
125 HAUS8  
Proximity Label-MS Homo sapiens
126 VCP 7415
Affinity Capture-MS Homo sapiens
127 SIPA1L2  
Proximity Label-MS Homo sapiens
128 OGT 8473
Reconstituted Complex Homo sapiens
129 AKAP11 11215
Proximity Label-MS Homo sapiens
130 TCHP  
Proximity Label-MS Homo sapiens
131 NRBF2  
Proximity Label-MS Homo sapiens
132 CEPT1 10390
Proximity Label-MS Homo sapiens
133 PLK1 5347
Proximity Label-MS Homo sapiens
134 MIA3 375056
Proximity Label-MS Homo sapiens
135 KRT14 3861
Cross-Linking-MS (XL-MS) Homo sapiens
136 NOS2  
Affinity Capture-MS Homo sapiens
137 BICD2 23299
Proximity Label-MS Homo sapiens
138 YWHAQ 10971
Affinity Capture-MS Homo sapiens
139 CCDC22 28952
Proximity Label-MS Homo sapiens
140 EIF4ENIF1 56478
Proximity Label-MS Homo sapiens
141 HECTD1 25831
Proximity Label-MS Homo sapiens
142 ARHGEF12 23365
Proximity Label-MS Homo sapiens
143 EYA4 2070
Proximity Label-MS Homo sapiens
144 CEP72  
Proximity Label-MS Homo sapiens
145 MAPK8 5599
Affinity Capture-Western Homo sapiens
146 ANKRD26 22852
Proximity Label-MS Homo sapiens
147 HAUS7  
Proximity Label-MS Homo sapiens
148 COG4 25839
Proximity Label-MS Homo sapiens
149 CYLD  
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
150 MPHOSPH9  
Proximity Label-MS Homo sapiens
151 USP32 84669
Affinity Capture-MS Homo sapiens
152 SSX2IP  
Proximity Label-MS Homo sapiens
153 YWHAE 7531
Proximity Label-MS Homo sapiens
154 WDR6 11180
Proximity Label-MS Homo sapiens
155 PHLPP1  
Proximity Label-MS Homo sapiens
156 KRT72 140807
Cross-Linking-MS (XL-MS) Homo sapiens
157 IFT57 55081
Proximity Label-MS Homo sapiens
158 HSPA5 3309
Reconstituted Complex Homo sapiens
159 PLAT 5327
Reconstituted Complex Homo sapiens
160 FAM83B  
Proximity Label-MS Homo sapiens
161 UNK  
Proximity Label-MS Homo sapiens
162 MAP7 9053
Proximity Label-MS Homo sapiens
163 TUBB2A 7280
Proximity Label-MS Homo sapiens
164 METTL14  
Affinity Capture-MS Homo sapiens
165 KIF15 56992
Proximity Label-MS Homo sapiens
166 KRT33B 3884
Two-hybrid Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
167 KRT25 147183
Two-hybrid Homo sapiens
168 TRIM36  
Proximity Label-MS Homo sapiens
169 TBKBP1  
Proximity Label-MS Homo sapiens
170 GLMN 11146
Proximity Label-MS Homo sapiens
171 DOCK7 85440
Proximity Label-MS Homo sapiens
172 PNN 5411
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
173 KRT35 3886
Two-hybrid Homo sapiens
174 CAMSAP3  
Proximity Label-MS Homo sapiens
175 AKAP9 10142
Proximity Label-MS Homo sapiens
176 IQCB1  
Affinity Capture-MS Homo sapiens
177 ANXA1 301
Affinity Capture-MS Homo sapiens
178 EPPK1 83481
Proximity Label-MS Homo sapiens
179 TJP1 7082
Affinity Capture-MS Homo sapiens
180 TRAF6 7189
Affinity Capture-Western Homo sapiens
181 CUL3 8452
Affinity Capture-MS Homo sapiens
182 PUM1 9698
Proximity Label-MS Homo sapiens
183 CCP110  
Proximity Label-MS Homo sapiens
184 CLN5  
Affinity Capture-MS Homo sapiens
185 IKBKAP 8518
Proximity Label-MS Homo sapiens
186 FBXO6 26270
Affinity Capture-MS Homo sapiens
187 TNRC6B  
Proximity Label-MS Homo sapiens
188 FN1 2335
Affinity Capture-MS Homo sapiens
189 KRT27 342574
Two-hybrid Homo sapiens
190 PLEKHA5 54477
Proximity Label-MS Homo sapiens
191 SCYL2 55681
Proximity Label-MS Homo sapiens
192 CDK5RAP2 55755
Proximity Label-MS Homo sapiens
193 ASB12  
Affinity Capture-MS Homo sapiens
194 LZTS2 84445
Proximity Label-MS Homo sapiens
195 KRT15 3866
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
196 BIRC6 57448
Proximity Label-MS Homo sapiens
197 ANKRD52 283373
Proximity Label-MS Homo sapiens
198 CCDC77  
Proximity Label-MS Homo sapiens
199 KNSTRN  
Proximity Label-MS Homo sapiens
200 TADA2A  
Affinity Capture-MS Homo sapiens
201 KIF1BP 26128
Proximity Label-MS Homo sapiens
202 MYC  
Affinity Capture-MS Homo sapiens
203 NIN 51199
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
204 CNTROB  
Proximity Label-MS Homo sapiens
205 USP9X 8239
Proximity Label-MS Homo sapiens
206 CAMSAP1 157922
Proximity Label-MS Homo sapiens
207 SEC16A 9919
Proximity Label-MS Homo sapiens
208 CEP85  
Proximity Label-MS Homo sapiens
209 TXNL1 9352
Proximity Label-MS Homo sapiens
210 KRT23  
Cross-Linking-MS (XL-MS) Homo sapiens
211 CEP131 22994
Proximity Label-MS Homo sapiens
212 PTPN14 5784
Proximity Label-MS Homo sapiens
213 SIRT2 22933
Proximity Label-MS Homo sapiens
214 PPP6C 5537
Affinity Capture-MS Homo sapiens
215 KIAA1671  
Proximity Label-MS Homo sapiens
216 CRYBG3  
Proximity Label-MS Homo sapiens
217 HSPA4L 22824
Affinity Capture-MS Homo sapiens
218 ESYT2 57488
Proximity Label-MS Homo sapiens
219 KRT19 3880
Proximity Label-MS Homo sapiens
Two-hybrid Homo sapiens
Proximity Label-MS Homo sapiens
220 ZER1 10444
Affinity Capture-MS Homo sapiens
221 KRT16 3868
Two-hybrid Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
222 HAUS3  
Proximity Label-MS Homo sapiens
223 KRT33A  
Cross-Linking-MS (XL-MS) Homo sapiens
224 DSP 1832
Proximity Label-MS Homo sapiens
225 HAUS4  
Proximity Label-MS Homo sapiens
226 SMG7  
Proximity Label-MS Homo sapiens
227 UBR4 23352
Proximity Label-MS Homo sapiens
228 NES 10763
Proximity Label-MS Homo sapiens
229 KRT18 3875
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
230 ANKHD1-EIF4EBP3  
Proximity Label-MS Homo sapiens
231 ALG13 79868
Proximity Label-MS Homo sapiens
232 SPICE1  
Proximity Label-MS Homo sapiens
233 EIF3F 8665
Affinity Capture-MS Homo sapiens
234 DVL1 1855
Proximity Label-MS Homo sapiens
235 LRRC49  
Proximity Label-MS Homo sapiens
236 TP53 7157
Proximity Label-MS Homo sapiens
237 NUP205 23165
Proximity Label-MS Homo sapiens
238 KIAA0753  
Proximity Label-MS Homo sapiens
239 GRB2 2885
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
240 KRT36 8689
Two-hybrid Homo sapiens
241 SEC23IP 11196
Proximity Label-MS Homo sapiens
242 PLEC 5339
Proximity Label-MS Homo sapiens
243 NEK6 10783
Two-hybrid Homo sapiens
244 SYNJ1 8867
Proximity Label-MS Homo sapiens
245 VIM 7431
Proximity Label-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
246 STRN4 29888
Proximity Label-MS Homo sapiens
247 CENPJ 55835
Proximity Label-MS Homo sapiens
248 SDCCAG3  
Proximity Label-MS Homo sapiens
249 BUB1B  
Proximity Label-MS Homo sapiens
250 IKBKG 8517
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
251 ATP5B 506
Proximity Label-MS Homo sapiens
252 KRT73 319101
Cross-Linking-MS (XL-MS) Homo sapiens
253 CAPZA2 830
Proximity Label-MS Homo sapiens
254 SEPT10 151011
Proximity Label-MS Homo sapiens
255 TROAP  
Reconstituted Complex Homo sapiens
256 PPP1R9B 84687
Proximity Label-MS Homo sapiens
257 KRT28 162605
Two-hybrid Homo sapiens
258 RCHY1  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
259 HAUS5 23354
Proximity Label-MS Homo sapiens
260 KRT71 112802
Cross-Linking-MS (XL-MS) Homo sapiens
261 DNMBP 23268
Proximity Label-MS Homo sapiens
262 FAM83H 286077
Proximity Label-MS Homo sapiens
263 PKP1 5317
Reconstituted Complex Homo sapiens
264 YTHDF3  
Proximity Label-MS Homo sapiens
265 POU2F1 5451
Affinity Capture-MS Homo sapiens
266 SQSTM1 8878
Proximity Label-MS Homo sapiens
267 ESR1  
Reconstituted Complex Homo sapiens
268 CEP44  
Proximity Label-MS Homo sapiens
269 SCN4A  
Cross-Linking-MS (XL-MS) Homo sapiens
270 PSMC3 5702
Proximity Label-MS Homo sapiens
271 KRT24 192666
Two-hybrid Homo sapiens
272 RNF38  
Affinity Capture-MS Homo sapiens
273 CLASP1 23332
Proximity Label-MS Homo sapiens
274 OTUD4  
Affinity Capture-MS Homo sapiens
275 PPP1R13B  
Proximity Label-MS Homo sapiens
276 STXBP4 252983
Proximity Label-MS Homo sapiens
277 KRT38 8687
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
278 SPAG5 10615
Proximity Label-MS Homo sapiens
279 DENND4A 10260
Proximity Label-MS Homo sapiens
280 CAD 790
Proximity Label-MS Homo sapiens
281 PRKCE 5581
Affinity Capture-Western Homo sapiens
282 SOGA1 140710
Proximity Label-MS Homo sapiens
283 TTC3 7267
Proximity Label-MS Homo sapiens
284 PLEKHG1  
Proximity Label-MS Homo sapiens
285 SMG1 23049
Proximity Label-MS Homo sapiens
286 LIMD1 8994
Proximity Label-MS Homo sapiens
287 CDR2  
Proximity Label-MS Homo sapiens
288 XRCC6 2547
Proximity Label-MS Homo sapiens
289 KRT13 3860
Two-hybrid Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
290 PEX5 5830
Proximity Label-MS Homo sapiens
291 QRSL1  
Two-hybrid Homo sapiens
292 AR 367
Affinity Capture-MS Homo sapiens
293 MTCL1 23255
Proximity Label-MS Homo sapiens
294 NEFM 4741
Proximity Label-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
295 NEFL 4747
Cross-Linking-MS (XL-MS) Homo sapiens
296 NDC80 10403
Proximity Label-MS Homo sapiens
297 PSMC4 5704
Proximity Label-MS Homo sapiens
298 RAPGEF6 51735
Proximity Label-MS Homo sapiens
299 CAV1 857
Co-fractionation Homo sapiens
300 IPO9 55705
Proximity Label-MS Homo sapiens
301 THADA 63892
Proximity Label-MS Homo sapiens
302 Smn1 20595
Affinity Capture-MS Mus musculus
303 AIM1 202
Proximity Label-MS Homo sapiens
304 SIPA1L3  
Proximity Label-MS Homo sapiens
305 PJA2  
Proximity Label-MS Homo sapiens
View the network image/svg+xml
 Pathways in which KRT8 is involved
PathwayEvidenceSource
Developmental Biology TAS Reactome
Formation of the cornified envelope TAS Reactome
Keratinization TAS Reactome





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