Gene description for STRN4
Gene name
striatin, calmodulin binding protein 4
Gene symbol
STRN4
Other names/aliases
ZIN zinedin
Species
Homo sapiens
Database cross references - STRN4
ExoCarta
ExoCarta_29888
Entrez Gene
29888
HGNC
15721
MIM
614767
UniProt
Q9NRL3
STRN4 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells
26054723
Hepatocytes
26054723
Gene ontology annotations for STRN4
Experiment description of studies that identified STRN4 in exosomes
1
Experiment ID
236
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
✘
EV Membrane markers
✔
HSP90B1
EV Negative markers
✔
qNano
EV Particle analysis
Identified molecule
mRNA
Identification method
RNA Sequencing
PubMed ID
26054723
Organism
Homo sapiens
Experiment description
Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors
He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name
Carcinogenesis
Publication year
2015
Sample
Hepatocellular carcinoma cells
Sample name
MHCC97L
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.13-1.19 g/mL
Molecules identified in the study
Protein RNA
Methods used in the study
Western blotting Mass spectrometry RT-PCR RNA Sequencing
2
Experiment ID
237
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
✘
EV Membrane markers
✔
HSP90B1
EV Negative markers
✔
qNano
EV Particle analysis
Identified molecule
mRNA
Identification method
RNA Sequencing
PubMed ID
26054723
Organism
Homo sapiens
Experiment description
Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors
He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name
Carcinogenesis
Publication year
2015
Sample
Hepatocytes
Sample name
MIHA
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.13-1.19 g/mL
Molecules identified in the study
Protein RNA
Methods used in the study
Western blotting Mass spectrometry RNA Sequencing
Protein-protein interactions for STRN4
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
STRIP1
85369
Affinity Capture-MS
Homo sapiens
2
STK24
8428
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
3
STK25
10494
Affinity Capture-MS
Homo sapiens
4
SLC25A6
293
Two-hybrid
Homo sapiens
5
AK5
Two-hybrid
Homo sapiens
6
FLJ21168
Affinity Capture-MS
Homo sapiens
7
NBEA
Two-hybrid
Homo sapiens
8
ASNS
440
Two-hybrid
Homo sapiens
9
T3JAM
Affinity Capture-MS
Homo sapiens
10
CLDN12
9069
Two-hybrid
Homo sapiens
11
GDF9
2661
Two-hybrid
Homo sapiens
12
GTP
Two-hybrid
Homo sapiens
13
STRN3
29966
Affinity Capture-MS
Homo sapiens
14
MCC
4163
Affinity Capture-MS
Homo sapiens
15
STRN
Affinity Capture-MS
Homo sapiens
16
KLHDC2
Two-hybrid
Homo sapiens
17
STK26
51765
Affinity Capture-MS
Homo sapiens
18
PREI3
Affinity Capture-MS
Homo sapiens
19
PI4KA
5297
Two-hybrid
Homo sapiens
20
PDCD10
11235
Affinity Capture-MS
Homo sapiens
21
BAT1
Two-hybrid
Homo sapiens
22
DKFZp547A023
Affinity Capture-MS
Homo sapiens
23
PPP2R1A
5518
Affinity Capture-MS
Homo sapiens
24
PPP2CA
5515
Affinity Capture-MS
Homo sapiens
25
PPP2CB
5516
Affinity Capture-MS
Homo sapiens
26
CTTNBP2
Affinity Capture-MS
Homo sapiens
27
ECSIT
51295
Two-hybrid
Homo sapiens
View the network
image/svg+xml
Pathways in which STRN4 is involved
No pathways found