Gene description for NUP62
Gene name	nucleoporin 62kDa
Gene symbol	NUP62
Other names/aliases	IBSN SNDI p62
Species	Homo sapiens
Database cross references - NUP62
ExoCarta	ExoCarta_23636
Entrez Gene	23636
HGNC	8066
MIM	605815
UniProt	P37198
NUP62 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells	26054723

Gene ontology annotations for NUP62

Molecular Function     ubiquitin binding GO:0043130 ISS     protein binding GO:0005515 IPI     SH2 domain binding GO:0042169 ISS     receptor signaling complex scaffold activity GO:0030159 ISS     chromatin binding GO:0003682 NAS     nucleocytoplasmic transporter activity GO:0005487 NAS     thyroid hormone receptor binding GO:0046966 ISS     PTB domain binding GO:0051425 IEA     structural constituent of nuclear pore GO:0017056 IEA Biological Process     transcription, DNA-templated GO:0006351 ISS     transmembrane transport GO:0055085 TAS     positive regulation of transcription, DNA-templated GO:0045893 ISS     negative regulation of Ras protein signal transduction GO:0046580 IEA     viral transcription GO:0019083 TAS     negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 IEA     negative regulation of MAP kinase activity GO:0043407 IEA     regulation of glucose transport GO:0010827 TAS     gene expression GO:0010467 TAS     hormone-mediated signaling pathway GO:0009755 NAS     regulation of cellular response to heat GO:1900034 TAS     regulation of Ras protein signal transduction GO:0046578 NAS     mitotic cell cycle GO:0000278 TAS     negative regulation of programmed cell death GO:0043069 ISS     positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123 ISS     cellular response to heat GO:0034605 TAS     cell aging GO:0007569 IEA     mitotic nuclear envelope disassembly GO:0007077 TAS     positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 NAS     protein transport GO:0015031 IEA     protein sumoylation GO:0016925 TAS     cellular protein metabolic process GO:0044267 TAS     cell death GO:0008219 ISS     negative regulation of apoptotic process GO:0043066 ISS     negative regulation of cell proliferation GO:0008285 ISS     carbohydrate metabolic process GO:0005975 TAS     hexose transport GO:0008645 TAS     cell surface receptor signaling pathway GO:0007166 NAS     cytokine-mediated signaling pathway GO:0019221 TAS     small molecule metabolic process GO:0044281 TAS     post-translational protein modification GO:0043687 TAS     regulation of signal transduction GO:0009966 NAS     viral process GO:0016032 TAS     nucleocytoplasmic transport GO:0006913 NAS     mRNA transport GO:0051028 IEA     glucose transport GO:0015758 TAS     viral life cycle GO:0019058 TAS Subcellular Localization     intracellular membrane-bounded organelle GO:0043231 IDA     Flemming body GO:0090543 IDA     nuclear membrane GO:0031965 IDA     spindle pole GO:0000922 IEA     pore complex GO:0046930 NAS     ribonucleoprotein complex GO:0030529 IDA     nuclear pore GO:0005643 ISS     cytoplasm GO:0005737 NAS     nuclear envelope GO:0005635 TAS     nucleocytoplasmic shuttling complex GO:0031074 NAS