Gene description for XPOT
Gene name exportin, tRNA
Gene symbol XPOT
Other names/aliases XPO3
Species Homo sapiens
 Database cross references - XPOT
ExoCarta ExoCarta_11260
Vesiclepedia VP_11260
Entrez Gene 11260
HGNC 12826
MIM 603180
UniProt O43592  
 XPOT identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Chondrocytes 35931686    
Chondrocytes 35931686    
Embryonic kidney cells 36706192    
Embryonic kidney cells 36706192    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Mesenchymal stem cells 36408942    
Neuroblastoma cells 25944692    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Thymus 23844026    
 Gene ontology annotations for XPOT
Molecular Function
    tRNA binding GO:0000049 IBA
    tRNA binding GO:0000049 IDA
    protein binding GO:0005515 IPI
    small GTPase binding GO:0031267 IEA
Biological Process
    tRNA export from nucleus GO:0006409 IDA
    intracellular protein transport GO:0006886 IEA
    tRNA re-export from nucleus GO:0071528 IBA
Subcellular Localization
    nuclear pore GO:0005643 IBA
    nuclear pore GO:0005643 IDA
    nucleoplasm GO:0005654 IDA
    nucleoplasm GO:0005654 TAS
    cytoplasm GO:0005737 IBA
    cytoplasm GO:0005737 IDA
    cytosol GO:0005829 IDA
    cytosol GO:0005829 TAS
    nuclear matrix GO:0016363 IBA
 Experiment description of studies that identified XPOT in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
7
Experiment ID 1275
MISEV standards
Biophysical techniques
✔
CD9|TSG101|FLOT1|FLOT2|RAB35|RAB5A|GAPDH|TFRC|CD63|Alix
Enriched markers
✔
PCNA|CANX|GAPDH|HSP90AA1|HSP90B1
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 1280
MISEV standards
Biophysical techniques
✔
TSG101|CD9|FLOT1|FLOT2|RAB35|RAB5A|GAPDH|TFRC|CD63|Alix
Enriched markers
✔
PCNA|CANX|GAPDH|HSP90AA1|HSP90B1
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T - Fraction 5
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density 1.151 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
9
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
10
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
11
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
13
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
14
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
15
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
16
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for XPOT
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CD3EAP  
Proximity Label-MS Homo sapiens
2 CDC14B 8555
Proximity Label-MS Homo sapiens
3 UBE2H 7328
Affinity Capture-MS Homo sapiens
4 PSMA6 5687
Co-fractionation Homo sapiens
5 SPRTN  
Affinity Capture-MS Homo sapiens
6 ETV6  
Proximity Label-MS Homo sapiens
7 FBXO7 25793
Affinity Capture-MS Homo sapiens
8 PSMA4 5685
Co-fractionation Homo sapiens
9 NAA40  
Co-fractionation Homo sapiens
10 RPA2 6118
Proximity Label-MS Homo sapiens
11 USP5 8078
Co-fractionation Homo sapiens
12 NUP62 23636
Co-fractionation Homo sapiens
13 FBXO25  
Affinity Capture-MS Homo sapiens
14 EBNA-LP  
Affinity Capture-MS
15 SLC2A1 6513
Affinity Capture-MS Homo sapiens
16 C9orf78 51759
Affinity Capture-MS Homo sapiens
17 LOC100132735  
Protein-RNA Homo sapiens
18 AAR2 25980
Affinity Capture-MS Homo sapiens
19 ASXL1  
Affinity Capture-MS Homo sapiens
20 NUP160 23279
Co-fractionation Homo sapiens
21 APEX1 328
Co-fractionation Homo sapiens
22 KIAA1429 25962
Affinity Capture-MS Homo sapiens
23 Heatr2  
Affinity Capture-MS Mus musculus
24 XRCC1 7515
Affinity Capture-MS Homo sapiens
25 ERF  
Affinity Capture-MS Homo sapiens
26 B3GNT2 10678
Affinity Capture-MS Homo sapiens
27 WDR11 55717
Co-fractionation Homo sapiens
28 HLA-B 3106
Affinity Capture-MS Homo sapiens
29 NUP153 9972
Co-fractionation Homo sapiens
30 H2AFV 94239
Co-fractionation Homo sapiens
31 FBXW7  
Affinity Capture-MS Homo sapiens
32 IQGAP1 8826
Co-fractionation Homo sapiens
33 NUP93 9688
Co-fractionation Homo sapiens
34 POLR1E  
Proximity Label-MS Homo sapiens
35 XPO7 23039
Co-fractionation Homo sapiens
36 HSP90B1 7184
Co-fractionation Homo sapiens
37 EPHA1 2041
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
38 NUDCD1 84955
Co-fractionation Homo sapiens
39 RNF126  
Affinity Capture-MS Homo sapiens
40 USP7 7874
Co-fractionation Homo sapiens
41 GPR17 2840
Affinity Capture-MS Homo sapiens
42 NUP133 55746
Co-fractionation Homo sapiens
43 KRT8 3856
Proximity Label-MS Homo sapiens
44 CD70 970
Affinity Capture-MS Homo sapiens
45 P4HA1 5033
Co-fractionation Homo sapiens
46 NFRKB  
Co-fractionation Homo sapiens
47 Tube1  
Affinity Capture-MS Mus musculus
48 CTDP1 9150
Affinity Capture-MS Homo sapiens
49 PARK2  
Affinity Capture-MS Homo sapiens
50 P2RY8  
Affinity Capture-MS Homo sapiens
51 TRA2A 29896
Two-hybrid Homo sapiens
52 FAM60A  
Affinity Capture-MS Homo sapiens
53 ILVBL 10994
Affinity Capture-MS Homo sapiens
54 NUP107 57122
Co-fractionation Homo sapiens
55 COMTD1 118881
Affinity Capture-MS Homo sapiens
56 POU6F2  
Two-hybrid Homo sapiens
57 PTPRE 5791
Affinity Capture-MS Homo sapiens
58 RAN 5901
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
59 NTRK1 4914
Affinity Capture-MS Homo sapiens
60 GPR182  
Affinity Capture-MS Homo sapiens
61 BICD2 23299
Co-fractionation Homo sapiens
62 HDAC5 10014
Affinity Capture-MS Homo sapiens
63 CAMKK2 10645
Affinity Capture-MS Homo sapiens
64 CEBPA  
Protein-peptide Homo sapiens
65 TTLL12 23170
Co-fractionation Homo sapiens
66 CA9 768
Affinity Capture-MS Homo sapiens
67 UPK2 7379
Affinity Capture-MS Homo sapiens
68 PSMA3 5684
Co-fractionation Homo sapiens
69 EFNA4  
Affinity Capture-MS Homo sapiens
70 CLN3 1201
Affinity Capture-MS Homo sapiens
71 PAPSS1 9061
Co-fractionation Homo sapiens
72 NASP 4678
Co-fractionation Homo sapiens
73 ARRDC4  
Affinity Capture-MS Homo sapiens
74 TPR 7175
Co-fractionation Homo sapiens
75 ECT2 1894
Affinity Capture-MS Homo sapiens
76 SIRT7  
Affinity Capture-MS Homo sapiens
77 IQCB1  
Affinity Capture-MS Homo sapiens
78 GCSH 2653
Co-fractionation Homo sapiens
79 PTPRA 5786
Affinity Capture-MS Homo sapiens
80 KRT75 9119
Two-hybrid Homo sapiens
81 CD274 29126
Affinity Capture-MS Homo sapiens
82 NUP88 4927
Co-fractionation Homo sapiens
83 CUL3 8452
Affinity Capture-MS Homo sapiens
84 EGFR 1956
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
85 FBXO6 26270
Affinity Capture-MS Homo sapiens
86 ARMC6 93436
Affinity Capture-MS Homo sapiens
87 Hsph1 15505
Affinity Capture-MS Mus musculus
88 UBA2 10054
Co-fractionation Homo sapiens
89 NEFM 4741
Proximity Label-MS Homo sapiens
90 RPA3 6119
Proximity Label-MS Homo sapiens
91 MCMBP 79892
Co-fractionation Homo sapiens
92 TXNL1 9352
Co-fractionation Homo sapiens
93 FAM46A  
Affinity Capture-MS Homo sapiens
94 PTPRN  
Affinity Capture-MS Homo sapiens
95 ETV3  
Affinity Capture-MS Homo sapiens
96 HDLBP 3069
Reconstituted Complex Homo sapiens
97 DDRGK1 65992
Affinity Capture-MS Homo sapiens
98 RNF2  
Affinity Capture-MS Homo sapiens
99 AKAP1 8165
Proximity Label-MS Homo sapiens
100 RAE1 8480
Co-fractionation Homo sapiens
101 HUWE1 10075
Affinity Capture-MS Homo sapiens
102 EML1 2009
Co-fractionation Homo sapiens
103 HIF1A 3091
Affinity Capture-MS Homo sapiens
104 STUB1 10273
Co-fractionation Homo sapiens
105 PSMB2 5690
Co-fractionation Homo sapiens
106 TAF6 6878
Co-fractionation Homo sapiens
107 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
108 NUP205 23165
Co-fractionation Homo sapiens
109 GRB2 2885
Co-fractionation Homo sapiens
110 FBXL6  
Affinity Capture-MS Homo sapiens
111 HMGB1 3146
Co-fractionation Homo sapiens
112 MFSD4  
Affinity Capture-MS Homo sapiens
113 HDAC6 10013
Affinity Capture-MS Homo sapiens
114 TPTE  
Affinity Capture-MS Homo sapiens
115 CUL5 8065
Affinity Capture-MS Homo sapiens
116 NUP98 4928
Co-fractionation Homo sapiens
117 HTR6  
Affinity Capture-MS Homo sapiens
118 PSMA1 5682
Co-fractionation Homo sapiens
119 Samm50  
Affinity Capture-MS Mus musculus
120 ACTA1 58
Co-fractionation Homo sapiens
121 C16orf72 29035
Affinity Capture-MS Homo sapiens
122 AIRE  
Affinity Capture-MS Homo sapiens
123 DPF3  
Affinity Capture-MS Homo sapiens
124 SERBP1 26135
Affinity Capture-MS Homo sapiens
125 EIF5A 1984
Co-fractionation Homo sapiens
126 KIR2DL4  
Affinity Capture-MS Homo sapiens
127 KRAS 3845
Synthetic Lethality Homo sapiens
128 C9orf72  
Affinity Capture-MS Homo sapiens
129 MYC  
Affinity Capture-MS Homo sapiens
130 RBCK1  
Co-fractionation Homo sapiens
131 RANBP2 5903
Co-fractionation Homo sapiens
132 EP300 2033
Affinity Capture-MS Homo sapiens
133 S1PR4  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which XPOT is involved
PathwayEvidenceSource
Metabolism of RNA TAS Reactome
tRNA processing TAS Reactome
tRNA processing in the nucleus TAS Reactome





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here