Gene description for PRPF31
Gene name pre-mRNA processing factor 31
Gene symbol PRPF31
Other names/aliases NY-BR-99
PRP31
RP11
SNRNP61
Species Homo sapiens
 Database cross references - PRPF31
ExoCarta ExoCarta_26121
Vesiclepedia VP_26121
Entrez Gene 26121
HGNC 15446
MIM 606419
UniProt Q8WWY3  
 PRPF31 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Mesenchymal stem cells 36408942    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
 Gene ontology annotations for PRPF31
Molecular Function
    RNA binding GO:0003723 HDA
    protein binding GO:0005515 IPI
    U4 snRNA binding GO:0030621 IDA
    U4atac snRNA binding GO:0030622 IDA
    protein-macromolecule adaptor activity GO:0030674 IDA
    identical protein binding GO:0042802 IPI
    ribonucleoprotein complex binding GO:0043021 IDA
    snRNP binding GO:0070990 IPI
Biological Process
    spliceosomal tri-snRNP complex assembly GO:0000244 IDA
    spliceosomal tri-snRNP complex assembly GO:0000244 IDA
    spliceosomal tri-snRNP complex assembly GO:0000244 IMP
    mRNA splicing, via spliceosome GO:0000398 IBA
    mRNA splicing, via spliceosome GO:0000398 IC
    mRNA splicing, via spliceosome GO:0000398 IDA
    mRNA splicing, via spliceosome GO:0000398 IDA
    mRNA splicing, via spliceosome GO:0000398 NAS
    snoRNA localization GO:0048254 IMP
    ribonucleoprotein complex localization GO:0071166 IMP
Subcellular Localization
    nucleus GO:0005634 IDA
    nucleus GO:0005634 NAS
    nucleoplasm GO:0005654 IDA
    nucleoplasm GO:0005654 TAS
    U2-type spliceosomal complex GO:0005684 IC
    U4 snRNP GO:0005687 IBA
    U4 snRNP GO:0005687 IDA
    U4atac snRNP GO:0005690 IDA
    U4atac snRNP GO:0005690 TAS
    Cajal body GO:0015030 IDA
    nuclear speck GO:0016607 IDA
    U4/U6 x U5 tri-snRNP complex GO:0046540 IDA
    U4/U6 x U5 tri-snRNP complex GO:0046540 IPI
    U2-type precatalytic spliceosome GO:0071005 IDA
    precatalytic spliceosome GO:0071011 IBA
    MLL1 complex GO:0071339 IDA
    spliceosomal tri-snRNP complex GO:0097526 IBA
 Experiment description of studies that identified PRPF31 in sEVs
1
Experiment ID 489
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
6
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
7
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
9
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
11
Experiment ID 488
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
12
Experiment ID 211
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 212
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
15
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PRPF31
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SIAH1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
2 UBE2H 7328
Affinity Capture-MS Homo sapiens
3 ZFP64  
Two-hybrid Homo sapiens
4 ZNF668  
Two-hybrid Homo sapiens
5 SUFU 51684
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 ZNF792 126375
Two-hybrid Homo sapiens
7 KHDRBS3  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
8 TXNIP 10628
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
9 SNRPG 6637
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 UBL4A 8266
Affinity Capture-MS Homo sapiens
11 SNRPE 6635
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
12 COIL  
Proximity Label-MS Homo sapiens
13 Prpf8 192159
Affinity Capture-MS Mus musculus
14 KPNA1 3836
Affinity Capture-Western Homo sapiens
15 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
16 PRICKLE1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
17 KIFC3 3801
Two-hybrid Homo sapiens
18 AES 166
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
19 ZNF48  
Two-hybrid Homo sapiens
20 REL 5966
Two-hybrid Homo sapiens
21 HIST1H2BG 8339
Proximity Label-MS Homo sapiens
22 ACTC1 70
Proximity Label-MS Homo sapiens
23 USP39 10713
Affinity Capture-MS Homo sapiens
24 NOP56 10528
Proximity Label-MS Homo sapiens
25 RPS19 6223
Affinity Capture-MS Homo sapiens
26 RPL10 6134
Affinity Capture-MS Homo sapiens
27 TOP1 7150
Affinity Capture-MS Homo sapiens
28 LSM4 25804
Affinity Capture-MS Homo sapiens
29 ZNF71  
Two-hybrid Homo sapiens
30 SSB 6741
Affinity Capture-MS Homo sapiens
31 PRPF3  
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
32 PHF5A 84844
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
33 DVL3 1857
Two-hybrid Homo sapiens
34 DIEXF  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
35 FBRS 64319
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
36 SNRPF 6636
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
37 OSBPL1A 114876
Affinity Capture-MS Homo sapiens
38 STX11 8676
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
39 CAPNS2 84290
Two-hybrid Homo sapiens
40 CENPA  
Proximity Label-MS Homo sapiens
41 APEX1 328
Proximity Label-MS Homo sapiens
42 KIAA1429 25962
Affinity Capture-MS Homo sapiens
43 Pqbp1  
Affinity Capture-MS Mus musculus
44 PARK2  
Affinity Capture-MS Homo sapiens
45 PLEKHG4  
Two-hybrid Homo sapiens
46 TBC1D22B  
Affinity Capture-MS Homo sapiens
47 RNPS1 10921
Affinity Capture-MS Homo sapiens
48 ZNF408  
Two-hybrid Homo sapiens
49 CEP70  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
50 CHAF1A  
Affinity Capture-MS Homo sapiens
51 UBE2O 63893
Affinity Capture-MS Homo sapiens
52 USH1G  
Two-hybrid Homo sapiens
53 SF3B1 23451
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
54 Srsf9  
Two-hybrid Mus musculus
55 TRIM14 9830
Two-hybrid Homo sapiens
56 COPS5 10987
Affinity Capture-MS Homo sapiens
57 PRC1 9055
Affinity Capture-MS Homo sapiens
58 KRT40  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
59 AGO3  
Affinity Capture-MS Homo sapiens
60 RBMY1F  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
61 SNRPC 6631
Affinity Capture-MS Homo sapiens
62 FBL 2091
Co-fractionation Homo sapiens
63 CALCOCO2  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
64 PRPF4B 8899
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
65 OBSL1 23363
Affinity Capture-MS Homo sapiens
66 SF3A2 8175
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
67 KRT31 3881
Two-hybrid Homo sapiens
68 CDR2L  
Two-hybrid Homo sapiens
69 EIF3E 3646
Two-hybrid Homo sapiens
70 Wbp11  
Affinity Capture-MS Mus musculus
71 RANBP9 10048
Affinity Capture-MS Homo sapiens
72 TUT1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
73 RNU4ATAC  
Affinity Capture-Western Homo sapiens
74 HAP1  
Two-hybrid Homo sapiens
75 KRTAP19-5  
Two-hybrid Homo sapiens
76 MTHFR 4524
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
77 WIZ 58525
Affinity Capture-MS Homo sapiens
78 MECP2 4204
Affinity Capture-MS Homo sapiens
79 POLR1E  
Proximity Label-MS Homo sapiens
80 SNX27 81609
Affinity Capture-MS Homo sapiens
81 MDFI  
Two-hybrid Homo sapiens
82 RBM42  
Affinity Capture-MS Homo sapiens
83 CARD14  
Two-hybrid Homo sapiens
84 TFIP11  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
85 KCTD6  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
86 KIF14 9928
Affinity Capture-MS Homo sapiens
87 RBMX 27316
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
88 GOLGA6L9  
Two-hybrid Homo sapiens
89 TRIM41 90933
Two-hybrid Homo sapiens
90 PRPF6 24148
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
91 MTUS2 23281
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
92 WBP4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
93 ZNF24  
Two-hybrid Homo sapiens
94 PRPF8 10594
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
95 PPIH 10465
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
96 NCKIPSD 51517
Two-hybrid Homo sapiens
97 TAF10 6881
Affinity Capture-MS Homo sapiens
98 MEPCE 56257
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
99 RBM4 5936
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
100 CCDC33 80125
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
101 KRTAP10-1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
102 PPP1R16A 84988
Two-hybrid Homo sapiens
103 LHX8  
Two-hybrid Homo sapiens
104 PSMD14 10213
Affinity Capture-MS Homo sapiens
105 APOBEC3C 27350
Two-hybrid Homo sapiens
106 GOLGA2 2801
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
107 KRT35 3886
Two-hybrid Homo sapiens
108 HIST1H3E 8353
Affinity Capture-MS Homo sapiens
109 SNRNP200 23020
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
110 MEIS3  
Two-hybrid Homo sapiens
111 TFDP1  
Co-fractionation Homo sapiens
112 MIPOL1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
113 SNRPB 6628
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
114 SNRPD1 6632
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
115 PNMA3  
Two-hybrid Homo sapiens
116 TTC21B 79809
Affinity Capture-MS Homo sapiens
117 VCP 7415
Affinity Capture-MS Homo sapiens
118 CYSRT1 375791
Two-hybrid Homo sapiens
119 NTRK1 4914
Affinity Capture-MS Homo sapiens
120 RPL31 6160
Proximity Label-MS Homo sapiens
121 ZNF837  
Two-hybrid Homo sapiens
122 IFI16 3428
Affinity Capture-MS Homo sapiens
123 RAD18  
Affinity Capture-MS Homo sapiens
124 SNRPB2 6629
Co-fractionation Homo sapiens
125 PNMA2  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
126 RNU6ATAC  
Affinity Capture-Western Homo sapiens
127 SNRPN 6638
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
128 RUNDC3A  
Two-hybrid Homo sapiens
129 HECTD1 25831
Affinity Capture-MS Homo sapiens
130 ASB15 142685
Two-hybrid Homo sapiens
131 CTR9 9646
Affinity Capture-MS Homo sapiens
132 PAK7  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
133 PHC2  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
134 FASTK  
Two-hybrid Homo sapiens
135 PRPF31 26121
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
136 CTNNBL1 56259
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
137 CYLD  
Affinity Capture-MS Homo sapiens
138 SF3A3 10946
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
139 BZW1 9689
Affinity Capture-MS Homo sapiens
140 SSX2IP  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
141 CD3EAP  
Proximity Label-MS Homo sapiens
142 CCDC57 284001
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
143 NOTCH2NL 388677
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
144 GAN 8139
Affinity Capture-MS Homo sapiens
145 OGT 8473
Reconstituted Complex Homo sapiens
146 OLA1 29789
Affinity Capture-MS Homo sapiens
147 RBM39 9584
Affinity Capture-MS Homo sapiens
148 HES7 84667
Two-hybrid Homo sapiens
149 USP4 7375
Affinity Capture-MS Homo sapiens
150 KRTAP1-3  
Two-hybrid Homo sapiens
151 NR4A1  
Affinity Capture-MS Homo sapiens
152 STRN3 29966
Co-fractionation Homo sapiens
153 LBX1  
Two-hybrid Homo sapiens
154 RBMY1A1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
155 KANK2 25959
Two-hybrid Homo sapiens
156 XPO1 7514
Affinity Capture-MS Homo sapiens
157 USP15 9958
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
158 KRTAP6-3  
Two-hybrid Homo sapiens
159 NCAPH2  
Two-hybrid Homo sapiens
160 CD2BP2 10421
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
161 ZNF622 90441
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
162 KRTAP10-8  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
163 RBMY1J  
Two-hybrid Homo sapiens
164 PRKAR1A 5573
Co-fractionation Homo sapiens
165 COPS8 10920
Affinity Capture-MS Homo sapiens
166 CUL3 8452
Affinity Capture-MS Homo sapiens
167 XAB2 56949
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
168 EGFR 1956
Negative Genetic Homo sapiens
169 ZNF250  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
170 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
171 KRTAP10-3  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
172 FSD2 123722
Two-hybrid Homo sapiens
173 VWC2  
Two-hybrid Homo sapiens
174 KPNA2 3838
Affinity Capture-Western Homo sapiens
175 SART1 9092
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
176 BHLHB9 80823
Two-hybrid Homo sapiens
177 CCNDBP1 23582
Two-hybrid Homo sapiens
178 SF3A1 10291
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
179 EFTUD2 9343
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
180 LZTS2 84445
Two-hybrid Homo sapiens
181 KRT15 3866
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
182 FANCA  
Two-hybrid Homo sapiens
183 TADA2A  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
184 IFT46 56912
Affinity Capture-MS Homo sapiens
185 RPA3 6119
Proximity Label-MS Homo sapiens
186 LSM3 27258
Affinity Capture-MS Homo sapiens
187 C1QTNF1 114897
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
188 LSM6 11157
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
189 TRIM27  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
190 NHP2L1 4809
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
191 HSPA4 3308
Co-fractionation Homo sapiens
192 SART3 9733
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
193 ZNF587  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
194 DDRGK1 65992
Affinity Capture-MS Homo sapiens
195 SF3B3 23450
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
196 UBE2N 7334
Affinity Capture-MS Homo sapiens
197 Rpl35 66489
Affinity Capture-MS Mus musculus
198 SNRPD3 6634
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
199 FSCN1 6624
Affinity Capture-MS Homo sapiens
200 UPF2 26019
Co-fractionation Homo sapiens
201 ZNF417  
Two-hybrid Homo sapiens
202 CCDC136  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
203 TSGA10  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
204 MID2 11043
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
205 SNRPD2 6633
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
206 Sart1  
Affinity Capture-MS Mus musculus
207 Sf3a3 75062
Two-hybrid Mus musculus
208 AHSA1 10598
Affinity Capture-MS Homo sapiens
209 CLPP 8192
Proximity Label-MS Homo sapiens
210 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
211 TP53BP2  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
212 HNRNPH2 3188
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
213 PARP1 142
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
214 CPSF6 11052
Affinity Capture-MS Homo sapiens
215 FANCC 2176
Two-hybrid Homo sapiens
216 PRDM14  
Two-hybrid Homo sapiens
217 Atp7a  
Affinity Capture-MS Mus musculus
218 RBM25 58517
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
219 WWOX 51741
Affinity Capture-MS Homo sapiens
220 SSRP1 6749
Affinity Capture-MS Homo sapiens
221 ZNF746  
Affinity Capture-MS Homo sapiens
222 FOXB1  
Affinity Capture-MS Homo sapiens
223 CDCA7L  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
224 MEN1 4221
Affinity Capture-MS Homo sapiens
225 CCDC70  
Two-hybrid Homo sapiens
226 SLAIN1 122060
Two-hybrid Homo sapiens
227 SNRPA 6626
Affinity Capture-MS Homo sapiens
228 ZNF774  
Two-hybrid Homo sapiens
229 SMURF1 57154
Affinity Capture-MS Homo sapiens
230 RPAP2  
Affinity Capture-MS Homo sapiens
231 MKRN3  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
232 KRTAP4-11  
Two-hybrid Homo sapiens
233 KRTAP1-1  
Two-hybrid Homo sapiens
234 RBAK  
Two-hybrid Homo sapiens
235 CCDC106  
Two-hybrid Homo sapiens
236 PNMA1 9240
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
237 UBXN11  
Two-hybrid Homo sapiens
238 LSM5  
Affinity Capture-MS Homo sapiens
239 DDX23 9416
Co-fractionation Homo sapiens
240 NIFK 84365
Proximity Label-MS Homo sapiens
241 HNRNPK 3190
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
242 Prpf3 70767
Affinity Capture-MS Mus musculus
243 ESR1  
Affinity Capture-MS Homo sapiens
244 UFL1 23376
Affinity Capture-MS Homo sapiens
245 KHDRBS2  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
246 SNRNP40 9410
Affinity Capture-MS Homo sapiens
247 CEBPA  
Protein-peptide Homo sapiens
248 LSM7  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
249 FXR1 8087
Two-hybrid Homo sapiens
250 PSTPIP1 9051
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
251 RPS24 6229
Proximity Label-MS Homo sapiens
252 ZSCAN22  
Two-hybrid Homo sapiens
253 JAKMIP2  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
254 TRIM23 373
Two-hybrid Homo sapiens
255 CIT 11113
Affinity Capture-MS Homo sapiens
256 BICD2 23299
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
257 METTL3  
Affinity Capture-MS Homo sapiens
258 LDOC1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
259 EXOSC8  
Two-hybrid Homo sapiens
260 PDE4DIP 9659
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
261 PRPF4 9128
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
262 KRAS 3845
Synthetic Growth Defect Homo sapiens
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
263 Ufl1  
Affinity Capture-MS Mus musculus
264 GNB2L1 10399
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
265 ZNF473 25888
Two-hybrid Homo sapiens
266 TMCC2  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
267 RC3H1 149041
Affinity Capture-MS Homo sapiens
268 HSF2BP  
Two-hybrid Homo sapiens
269 SNRPA1 6627
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
270 KRT34  
Two-hybrid Homo sapiens
271 ALS2CR12  
Two-hybrid Homo sapiens
272 PRMT1 3276
Affinity Capture-MS Homo sapiens
273 ZFP69B  
Two-hybrid Homo sapiens
274 LURAP1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
275 SRSF3 6428
Two-hybrid Homo sapiens
276 EP300 2033
Affinity Capture-MS Homo sapiens
277 ARIH1 25820
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
278 EFEMP2 30008
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
279 KRTAP10-9  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here