Experiment description of studies that identified PPP1R8 in exosomes

1 Experiment ID 237 ISEV standards ✔ EM EV Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH EV Cytosolic markers ✘ EV Membrane markers ✔ HSP90B1 EV Negative markers ✔ qNano EV Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N Journal name Carcinogenesis Publication year 2015 Sample Hepatocytes Sample name MIHA Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RNA Sequencing

Protein-protein interactions for PPP1R8

Protein Interactor ExoCarta ID Identification method PubMed Species 1 DKFZP564O0523   Two-hybrid Homo sapiens 2 LYN 4067 Invitro Homo sapiens 3 NME2 4831 Affinity Capture-MS Homo sapiens 4 PPP1CA 5499 Affinity Capture-MS Homo sapiens Reconstituted Complex Homo sapiens Reconstituted Complex Homo sapiens 5 STC2 8614 Two-hybrid Homo sapiens 6 SF3B1 23451 Two-hybrid Homo sapiens Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens 7 PRKACA 5566 Biochemical Activity Homo sapiens 8 PPP1CB 5500 Affinity Capture-MS Homo sapiens 9 CRMP1 1400 Two-hybrid Homo sapiens 10 HDAC2 3066 Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens 11 C14orf1 11161 Two-hybrid Homo sapiens 12 GBP2   Two-hybrid Homo sapiens 13 CDC5L 988 Invivo Homo sapiens Invitro Homo sapiens Two-hybrid Homo sapiens Affinity Capture-MS Homo sapiens 14 EED   Affinity Capture-Western Homo sapiens Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens 15 SETDB1   Two-hybrid Homo sapiens View the network

Pathways in which PPP1R8 is involved

No pathways found