Gene description for RICTOR
Gene name	RPTOR independent companion of MTOR, complex 2
Gene symbol	RICTOR
Other names/aliases	AVO3 PIA hAVO3
Species	Homo sapiens
Database cross references - RICTOR
ExoCarta	ExoCarta_253260
Entrez Gene	253260
HGNC	28611
MIM	609022
UniProt	Q6R327
RICTOR identified in exosomes derived from the following tissue/cell type
Neuroblastoma cells	25944692
Ovarian cancer cells	23333927
Ovarian cancer cells	23333927

Gene ontology annotations for RICTOR

Molecular Function     ribosome binding GO:0043022 IEA     protein binding GO:0005515 IPI     protein kinase binding GO:0019901 IPI Biological Process     positive regulation of actin filament polymerization GO:0030838 IEA     phosphatidylinositol-mediated signaling GO:0048015 TAS     regulation of protein kinase B signaling GO:0051896 IDA     TOR signaling GO:0031929 IEA     fibroblast growth factor receptor signaling pathway GO:0008543 TAS     embryo development GO:0009790 ISS     positive regulation of TOR signaling GO:0032008 IMP     positive regulation of protein kinase B signaling GO:0051897 IEA     positive regulation of endothelial cell proliferation GO:0001938 IEA     vascular endothelial growth factor receptor signaling pathway GO:0048010 TAS     epidermal growth factor receptor signaling pathway GO:0007173 TAS     positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 IEA     T cell costimulation GO:0031295 TAS     peptidyl-serine phosphorylation GO:0018105 IGI     actin cytoskeleton reorganization GO:0031532 IMP     innate immune response GO:0045087 TAS     regulation of actin cytoskeleton organization GO:0032956 IMP     neurotrophin TRK receptor signaling pathway GO:0048011 TAS     Fc-epsilon receptor signaling pathway GO:0038095 TAS Subcellular Localization     TORC2 complex GO:0031932 IDA     cytosol GO:0005829 TAS