Gene description for CTSB
Gene name	cathepsin B
Gene symbol	CTSB
Other names/aliases	APPS CPSB
Species	Homo sapiens
Database cross references - CTSB
ExoCarta	ExoCarta_1508
Entrez Gene	1508
HGNC	2527
MIM	116810
UniProt	P07858
CTSB identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells	26054723
Hepatocytes	26054723
Keratinocytes	19530224
Keratinocytes	19530224
Saliva	19199708
Thymus	23844026

Gene ontology annotations for CTSB

Molecular Function     protein binding GO:0005515 IPI     peptidase activity GO:0008233 IDA     proteoglycan binding GO:0043394 IPI     cysteine-type endopeptidase activity GO:0004197 IDA     cysteine-type peptidase activity GO:0008234 IDA     collagen binding GO:0005518 IDA Biological Process     extracellular matrix disassembly GO:0022617 TAS     proteolysis involved in cellular protein catabolic process GO:0051603 IDA     cellular response to thyroid hormone stimulus GO:0097067 IEP     extracellular matrix organization GO:0030198 TAS     proteolysis GO:0006508 IDA     toll-like receptor signaling pathway GO:0002224 TAS     epithelial cell differentiation GO:0030855 IEP     regulation of catalytic activity GO:0050790 IEA     innate immune response GO:0045087 TAS     collagen catabolic process GO:0030574 TAS     decidualization GO:0046697 IEA     regulation of apoptotic process GO:0042981 TAS Subcellular Localization     melanosome GO:0042470 IEA     nucleolus GO:0005730 IDA     extracellular region GO:0005576 TAS     mitochondrion GO:0005739 IEA     perinuclear region of cytoplasm GO:0048471 IDA     endolysosome lumen GO:0036021 TAS     intracellular membrane-bounded organelle GO:0043231 IDA     extracellular space GO:0005615 ISS     lysosome GO:0005764 IDA     intracellular GO:0005622 TAS     extracellular exosome GO:0070062 IDA