Gene description for S100A9
Gene name S100 calcium binding protein A9
Gene symbol S100A9
Other names/aliases 60B8AG
CAGB
CFAG
CGLB
L1AG
LIAG
MAC387
MIF
MRP14
NIF
P14
Species Homo sapiens
 Database cross references - S100A9
ExoCarta ExoCarta_6280
Vesiclepedia VP_6280
Entrez Gene 6280
HGNC 10499
MIM 123886
UniProt P06702  
 S100A9 identified in exosomes derived from the following tissue/cell type
Bladder cancer cells 20224111    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 34887515    
Liver cancer cells 25265333    
Liver cancer cells 25265333    
Liver cancer cells 25265333    
Platelets 25332113    
Platelets 25332113    
Platelets 25332113    
Saliva 19199708    
Urine 19056867    
Urine 22418980    
Urine 22418980    
 Gene ontology annotations for S100A9
Molecular Function
    calcium ion binding GO:0005509 IBA
    calcium ion binding GO:0005509 TAS
    protein binding GO:0005515 IPI
    microtubule binding GO:0008017 TAS
    zinc ion binding GO:0008270 TAS
    antioxidant activity GO:0016209 IEA
    Toll-like receptor 4 binding GO:0035662 TAS
    calcium-dependent protein binding GO:0048306 IBA
    arachidonate binding GO:0050544 TAS
    RAGE receptor binding GO:0050786 TAS
Biological Process
    leukocyte migration involved in inflammatory response GO:0002523 IBA
    leukocyte migration involved in inflammatory response GO:0002523 IDA
    chronic inflammatory response GO:0002544 IBA
    autophagy GO:0006914 IDA
    apoptotic process GO:0006915 IEA
    inflammatory response GO:0006954 TAS
    cell-cell signaling GO:0007267 TAS
    positive regulation of neuron projection development GO:0010976 ISS
    astrocyte development GO:0014002 IBA
    positive regulation of cell growth GO:0030307 TAS
    neutrophil chemotaxis GO:0030593 IBA
    neutrophil chemotaxis GO:0030593 IDA
    sequestering of zinc ion GO:0032119 TAS
    regulation of toll-like receptor signaling pathway GO:0034121 NAS
    autocrine signaling GO:0035425 IBA
    peptidyl-cysteine S-trans-nitrosylation GO:0035606 IDA
    modulation of process of another organism GO:0035821 IDA
    defense response to bacterium GO:0042742 TAS
    endothelial cell migration GO:0043542 IBA
    innate immune response GO:0045087 IEA
    positive regulation of inflammatory response GO:0050729 IDA
    defense response to fungus GO:0050832 TAS
    positive regulation of NF-kappaB transcription factor activity GO:0051092 TAS
    regulation of cytoskeleton organization GO:0051493 TAS
    regulation of respiratory burst involved in inflammatory response GO:0060264 NAS
    antimicrobial humoral immune response mediated by antimicrobial peptide GO:0061844 IBA
    antimicrobial humoral immune response mediated by antimicrobial peptide GO:0061844 IDA
    neutrophil aggregation GO:0070488 IBA
    neutrophil aggregation GO:0070488 IDA
    cellular oxidant detoxification GO:0098869 IEA
    positive regulation of cysteine-type endopeptidase activity GO:2001056 IDA
    positive regulation of intrinsic apoptotic signaling pathway GO:2001244 IDA
Subcellular Localization
    extracellular region GO:0005576 HDA
    extracellular region GO:0005576 TAS
    extracellular space GO:0005615 HDA
    extracellular space GO:0005615 IDA
    nucleus GO:0005634 HDA
    cytoplasm GO:0005737 IBA
    cytoplasm GO:0005737 IDA
    cytosol GO:0005829 TAS
    cytoskeleton GO:0005856 TAS
    plasma membrane GO:0005886 TAS
    secretory granule lumen GO:0034774 TAS
    collagen-containing extracellular matrix GO:0062023 HDA
    extracellular exosome GO:0070062 HDA
    calprotectin complex GO:1990660 IPI
    calprotectin complex GO:1990660 ISO
    S100A9 complex GO:1990662 IPI
 Experiment description of studies that identified S100A9 in exosomes
1
Experiment ID 76
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|GAPDH|HSP90|CD81|CD9|CD63|LAMP1|MHCI
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20224111    
Organism Homo sapiens
Experiment description Proteomics analysis of bladder cancer exosomes.
Authors "Welton JL, Khanna S, Giles PJ, Brennan P, Brewis IA, Staffurth J, Mason MD, Clayton A."
Journal name MCP
Publication year 2010
Sample Bladder cancer cells
Sample name HT1376
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.10-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF/TOF]
Western blotting
FACS
2
Experiment ID 494
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD151|CD63|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Osteoarthritic cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 496
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Healthy cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
7
Experiment ID 266
MISEV standards
✘ Biophysical techniques
✔
TSG101|Alix
Enriched markers
✔
CANX|HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25265333    
Organism Homo sapiens
Experiment description Quantitative Proteomic Analysis of Exosome Protein Content Changes Induced by Hepatitis B Virus in Huh-7 Cells Using SILAC Labeling and LC-MS/MS
Authors "Zhao X, Wu Y, Duan J, Ma Y, Shen Z, Wei L, Cui X, Zhang J, Xie Y, Liu J"
Journal name J Proteome Res
Publication year 2014
Sample Liver cancer cells
Sample name Huh-7 - Wild type
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 267
MISEV standards
✘ Biophysical techniques
✔
TSG101|Alix
Enriched markers
✔
CANX|HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25265333    
Organism Homo sapiens
Experiment description Quantitative Proteomic Analysis of Exosome Protein Content Changes Induced by Hepatitis B Virus in Huh-7 Cells Using SILAC Labeling and LC-MS/MS
Authors "Zhao X, Wu Y, Duan J, Ma Y, Shen Z, Wei L, Cui X, Zhang J, Xie Y, Liu J"
Journal name J Proteome Res
Publication year 2014
Sample Liver cancer cells
Sample name Huh-7 - Transfected with HBx plasmids
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
9
Experiment ID 268
MISEV standards
✘ Biophysical techniques
✔
TSG101|Alix
Enriched markers
✔
CANX|HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25265333    
Organism Homo sapiens
Experiment description Quantitative Proteomic Analysis of Exosome Protein Content Changes Induced by Hepatitis B Virus in Huh-7 Cells Using SILAC Labeling and LC-MS/MS
Authors "Zhao X, Wu Y, Duan J, Ma Y, Shen Z, Wei L, Cui X, Zhang J, Xie Y, Liu J"
Journal name J Proteome Res
Publication year 2014
Sample Liver cancer cells
Sample name Huh-7 - Transfected with HBx-null HBV replicon plasmids
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
10
Experiment ID 231
MISEV standards
✘ Biophysical techniques
✔
Alix|CD63|CD9
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Western blotting
Mass spectrometry
11
Experiment ID 232
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
12
Experiment ID 233
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 66
MISEV standards
✔
IEM
Biophysical techniques
✔
TSG101|Alix|CD63|CD81
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19199708    
Organism Homo sapiens
Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors "Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR"
Journal name JPR
Publication year 2009
Sample Saliva
Sample name Saliva
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
14
Experiment ID 63
MISEV standards
✘ Biophysical techniques
✔
AQP2
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
15
Experiment ID 196
MISEV standards
✔
EM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors "Raj DA, Fiume I, Capasso G, Pocsfalvi G."
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal high density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
16
Experiment ID 197
MISEV standards
✔
EM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors "Raj DA, Fiume I, Capasso G, Pocsfalvi G."
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal low density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for S100A9
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UBE2H 7328
Affinity Capture-MS Homo sapiens
2 RALY 22913
Affinity Capture-MS Homo sapiens
3 NME2P1 283458
Affinity Capture-MS Homo sapiens
4 ARHGAP21 57584
Affinity Capture-MS Homo sapiens
5 RPL26L1 51121
Affinity Capture-MS Homo sapiens
6 CBX1 10951
Affinity Capture-MS Homo sapiens
7 SERPINB4 6318
Affinity Capture-MS Homo sapiens
8 ARNT 405
Affinity Capture-MS Homo sapiens
9 ZNF326 284695
Co-fractionation Homo sapiens
10 MAGEA3  
Two-hybrid Homo sapiens
11 SHC1 6464
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
12 ATG5 9474
Proximity Label-MS Homo sapiens
13 PRPF8 10594
Co-fractionation Homo sapiens
14 ARHGEF26 26084
Affinity Capture-MS Homo sapiens
15 MARCH2  
Affinity Capture-MS Homo sapiens
16 FBXL19  
Affinity Capture-MS Homo sapiens
17 MAGEA1  
Two-hybrid Homo sapiens
18 SURF4 6836
Co-fractionation Homo sapiens
19 TLE3  
Co-fractionation Homo sapiens
20 CSTA 1475
Affinity Capture-MS Homo sapiens
21 ZIC1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
22 TRIM55  
Co-fractionation Homo sapiens
23 KDM4A  
Affinity Capture-MS Homo sapiens
24 ST7  
Affinity Capture-MS Homo sapiens
25 FNDC5  
Affinity Capture-MS Homo sapiens
26 PI4KA 5297
Affinity Capture-MS Homo sapiens
27 RHBDD1 84236
Affinity Capture-MS Homo sapiens
28 KIAA1429 25962
Affinity Capture-MS Homo sapiens
29 GPATCH2L  
Affinity Capture-MS Homo sapiens
30 KLK10 5655
Affinity Capture-MS Homo sapiens
31 RNPS1 10921
Co-fractionation Homo sapiens
32 B3GNT2 10678
Affinity Capture-MS Homo sapiens
33 RNF5  
Affinity Capture-MS Homo sapiens
34 TUBB 203068
Reconstituted Complex Homo sapiens
35 PSRC1  
Co-fractionation Homo sapiens
36 MCM2 4171
Affinity Capture-MS Homo sapiens
37 COPS5 10987
Affinity Capture-MS Homo sapiens
38 NUDT3 11165
Affinity Capture-MS Homo sapiens
39 MAPK14 1432
Biochemical Activity Homo sapiens
40 NR3C1 2908
Affinity Capture-MS Homo sapiens
41 SRSF3 6428
Co-fractionation Homo sapiens
42 USF2 7392
Affinity Capture-MS Homo sapiens
43 ARHGAP19  
Affinity Capture-MS Homo sapiens
44 CPLX1 10815
Co-fractionation Homo sapiens
45 SLX4  
Affinity Capture-MS Homo sapiens
46 PHF11 51131
Affinity Capture-MS Homo sapiens
47 APTX  
Affinity Capture-MS Homo sapiens
48 SERPINA1 5265
Affinity Capture-MS Homo sapiens
49 METTL23  
Affinity Capture-MS Homo sapiens
50 MYCN  
Affinity Capture-MS Homo sapiens
51 CCNC  
Affinity Capture-MS Homo sapiens
52 GNPAT 8443
Affinity Capture-MS Homo sapiens
53 NCSTN 23385
Co-fractionation Homo sapiens
54 RBM14 10432
Co-fractionation Homo sapiens
55 KIF14 9928
Affinity Capture-MS Homo sapiens
56 DDX19B 11269
Affinity Capture-MS Homo sapiens
57 SETD8  
Affinity Capture-MS Homo sapiens
58 NF2 4771
Affinity Capture-MS Homo sapiens
59 ZNF550  
Affinity Capture-MS Homo sapiens
60 PIP 5304
Affinity Capture-MS Homo sapiens
61 ING4  
Affinity Capture-MS Homo sapiens
62 UTP14A 10813
Co-fractionation Homo sapiens
63 RNF4 6047
Affinity Capture-MS Homo sapiens
64 DDX21 9188
Co-fractionation Homo sapiens
65 TTC39A 22996
Affinity Capture-MS Homo sapiens
66 SMARCA5 8467
Co-fractionation Homo sapiens
67 ZNF207 7756
Affinity Capture-MS Homo sapiens
68 SPDL1  
Affinity Capture-MS Homo sapiens
69 U2AF1 7307
Co-fractionation Homo sapiens
70 TRA2A 29896
Co-fractionation Homo sapiens
71 EIF2B5 8893
Affinity Capture-MS Homo sapiens
72 TUBA1A 7846
Reconstituted Complex Homo sapiens
73 ACIN1 22985
Co-fractionation Homo sapiens
74 SRRT 51593
Co-fractionation Homo sapiens
75 Vav2  
Affinity Capture-MS Mus musculus
76 TBC1D22B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
77 DEK 7913
Co-fractionation Homo sapiens
78 RIPPLY3  
Affinity Capture-MS Homo sapiens
79 TRIM21 6737
Affinity Capture-MS Homo sapiens
80 NTRK1 4914
Affinity Capture-MS Homo sapiens
81 PIGT 51604
Affinity Capture-MS Homo sapiens
82 IFI16 3428
Affinity Capture-MS Homo sapiens
83 U2AF2 11338
Co-fractionation Homo sapiens
84 S100A8 6279
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
85 SPRR2E  
Affinity Capture-MS Homo sapiens
86 TPBG 7162
Co-fractionation Homo sapiens
87 RPL36 25873
Affinity Capture-MS Homo sapiens
88 SF3B6 51639
Co-fractionation Homo sapiens
89 Arhgap18  
Affinity Capture-MS Mus musculus
90 CUL2 8453
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
91 TCEB3B  
Affinity Capture-MS Homo sapiens
92 SON 6651
Co-fractionation Homo sapiens
93 DDX39B 7919
Affinity Capture-MS Homo sapiens
94 OCRL 4952
Affinity Capture-MS Homo sapiens
95 CYLD  
Affinity Capture-MS Homo sapiens
96 DKK2  
Affinity Capture-MS Homo sapiens
97 CNR2  
Affinity Capture-MS Homo sapiens
98 HIST1H2AI 8329
Affinity Capture-MS Homo sapiens
99 PHF21B  
Affinity Capture-MS Homo sapiens
100 TEFM  
Affinity Capture-MS Homo sapiens
101 SRSF11 9295
Co-fractionation Homo sapiens
102 HNRNPD 3184
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
103 CASP14 23581
Affinity Capture-MS Homo sapiens
104 SARAF  
Affinity Capture-MS Homo sapiens
105 RBM39 9584
Co-fractionation Homo sapiens
106 SERPINB3 6317
Affinity Capture-MS Homo sapiens
107 PPP2R2B 5521
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
108 FANCD2  
Affinity Capture-MS Homo sapiens
109 AIFM1 9131
Affinity Capture-MS Homo sapiens
110 SRSF7 6432
Co-fractionation Homo sapiens
111 AGPAT1 10554
Affinity Capture-MS Homo sapiens
112 DOCK8 81704
Affinity Capture-MS Homo sapiens
113 NT5C1A  
Affinity Capture-MS Homo sapiens
114 NUBP2 10101
Co-fractionation Homo sapiens
115 TPR 7175
Co-fractionation Homo sapiens
116 RNF170 81790
Affinity Capture-MS Homo sapiens
117 FAM60A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
118 EPAS1  
Affinity Capture-MS Homo sapiens
119 CD2BP2 10421
Co-fractionation Homo sapiens
120 GTF3C1  
Co-fractionation Homo sapiens
121 SRSF5 6430
Co-fractionation Homo sapiens
122 SSSCA1 10534
Co-fractionation Homo sapiens
123 ERCC8  
Affinity Capture-MS Homo sapiens
124 S100A7 6278
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
125 NPPA  
Affinity Capture-MS Homo sapiens
126 EGFR 1956
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
127 NUAK1  
Affinity Capture-MS Homo sapiens
128 MYC  
Affinity Capture-MS Homo sapiens
129 ARRB2 409
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
130 VHL  
Affinity Capture-MS Homo sapiens
131 TAGLN 6876
Affinity Capture-MS Homo sapiens
132 SUSD3 203328
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
133 CDC42 998
Two-hybrid Homo sapiens
134 PRR4 11272
Affinity Capture-MS Homo sapiens
135 ARHGAP29 9411
Affinity Capture-MS Homo sapiens
136 PPP2R1A 5518
Affinity Capture-MS Homo sapiens
137 ARHGAP4 393
Affinity Capture-MS Homo sapiens
138 ZC3H18  
Co-fractionation Homo sapiens
139 S100B 6285
Two-hybrid Homo sapiens
140 TOP1 7150
Co-fractionation Homo sapiens
141 UPK1A 11045
Affinity Capture-MS Homo sapiens
142 PABPN1L  
Affinity Capture-MS Homo sapiens
143 DSTN 11034
Co-fractionation Homo sapiens
144 MATR3 9782
Co-fractionation Homo sapiens
145 SRSF10 10772
Co-fractionation Homo sapiens
146 MAGEA6  
Two-hybrid Homo sapiens
147 ILK 3611
Affinity Capture-MS Homo sapiens
148 PCYOX1 51449
Affinity Capture-MS Homo sapiens
149 LGALS7 3963
Affinity Capture-MS Homo sapiens
150 C18orf21  
Affinity Capture-MS Homo sapiens
151 STX17 55014
Affinity Capture-MS Homo sapiens
152 SUPT16H 11198
Co-fractionation Homo sapiens
153 SFMBT1 51460
Affinity Capture-MS Homo sapiens
154 HUWE1 10075
Affinity Capture-MS Homo sapiens
155 SART1 9092
Co-fractionation Homo sapiens
156 DHX15 1665
Co-fractionation Homo sapiens
157 SNCA 6622
Co-crystal Structure Homo sapiens
Reconstituted Complex Homo sapiens
158 ASB3 51130
Affinity Capture-MS Homo sapiens
159 RAD21 5885
Affinity Capture-Western Homo sapiens
160 SPOP  
Affinity Capture-MS Homo sapiens
161 SIRT6  
Affinity Capture-MS Homo sapiens
162 PARP1 142
Proximity Label-MS Homo sapiens
163 GRB2 2885
Affinity Capture-MS Homo sapiens
164 PAK7  
Affinity Capture-MS Homo sapiens
165 SSUH2  
Affinity Capture-MS Homo sapiens
166 GPN1  
Affinity Capture-MS Homo sapiens
167 DOCK5 80005
Affinity Capture-MS Homo sapiens
168 TTC4  
Affinity Capture-MS Homo sapiens
169 CALML5 51806
Affinity Capture-MS Homo sapiens
170 SH2D3A  
Affinity Capture-MS Homo sapiens
171 MCM5 4174
Affinity Capture-MS Homo sapiens
172 PSMB7 5695
Co-fractionation Homo sapiens
173 EGFL8  
Affinity Capture-MS Homo sapiens
174 SAP18 10284
Co-fractionation Homo sapiens
175 CUL5 8065
Affinity Capture-MS Homo sapiens
176 EDEM1  
Affinity Capture-MS Homo sapiens
177 SQSTM1 8878
Proximity Label-MS Homo sapiens
178 THRAP3 9967
Co-fractionation Homo sapiens
179 C1orf35  
Affinity Capture-MS Homo sapiens
180 TREX2  
Affinity Capture-MS Homo sapiens
181 PLEKHG4B 153478
Affinity Capture-MS Homo sapiens
182 EIF4A3 9775
Co-fractionation Homo sapiens
183 TRA2B 6434
Co-fractionation Homo sapiens
184 S100A9 6280
Co-crystal Structure Homo sapiens
Affinity Capture-Western Homo sapiens
Co-crystal Structure Homo sapiens
Affinity Capture-Western Homo sapiens
185 NCF2 4688
Reconstituted Complex Homo sapiens
186 VTN 7448
Co-fractionation Homo sapiens
187 TOP2B 7155
Co-fractionation Homo sapiens
188 ERCC3  
Affinity Capture-MS Homo sapiens
189 UNK  
Co-fractionation Homo sapiens
190 CHMP4C 92421
Affinity Capture-MS Homo sapiens
191 PSMA5 5686
Co-fractionation Homo sapiens
192 ARHGAP36  
Affinity Capture-MS Homo sapiens
193 ARRB1 408
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
194 LUCAT1  
Affinity Capture-RNA Homo sapiens
195 AIRE  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
196 TSPAN6 7105
Affinity Capture-MS Homo sapiens
197 PINK1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
198 PI4KAP1  
Affinity Capture-MS Homo sapiens
199 GOT1 2805
Affinity Capture-MS Homo sapiens
200 STK11 6794
Affinity Capture-MS Homo sapiens
201 SSRP1 6749
Co-fractionation Homo sapiens
202 TOPORS  
Affinity Capture-MS Homo sapiens
203 PDE4DIP 9659
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
204 MARCH4  
Affinity Capture-MS Homo sapiens
205 HNRNPU 3192
Co-fractionation Homo sapiens
206 OR2A4 79541
Affinity Capture-MS Homo sapiens
207 LTF 4057
Affinity Capture-MS Homo sapiens
208 DDX3X 1654
Affinity Capture-MS Homo sapiens
209 PPP2R2A 5520
Affinity Capture-MS Homo sapiens
210 GABPA 2551
Affinity Capture-MS Homo sapiens
211 CCR1  
Affinity Capture-MS Homo sapiens
212 LUC7L3 51747
Co-fractionation Homo sapiens
213 MECP2 4204
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here