Gene description for THAP11
Gene name THAP domain containing 11
Gene symbol THAP11
Other names/aliases CTG-B43a
CTG-B45d
HRIHFB2206
RONIN
Species Homo sapiens
 Database cross references - THAP11
ExoCarta ExoCarta_57215
Vesiclepedia VP_57215
Entrez Gene 57215
HGNC 23194
MIM 609119
UniProt Q96EK4  
 THAP11 identified in exosomes derived from the following tissue/cell type
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
 Gene ontology annotations for THAP11
Molecular Function
    RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 IBA
    RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 IDA
    DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 ISA
    DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227 IDA
    DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228 IEA
    DNA binding GO:0003677 IDA
    protein binding GO:0005515 IPI
    zinc ion binding GO:0008270 IDA
Biological Process
    negative regulation of transcription by RNA polymerase II GO:0000122 IDA
    regulation of transcription by RNA polymerase II GO:0006357 IBA
    cell population proliferation GO:0008283 IEA
    electron transport chain GO:0022900 IEA
    neuron differentiation GO:0030182 IEA
    negative regulation of neuron apoptotic process GO:0043524 IEA
    positive regulation of transcription by RNA polymerase II GO:0045944 IEA
    regulation of mitochondrial transcription GO:1903108 IEA
Subcellular Localization
    chromatin GO:0000785 ISA
    nucleoplasm GO:0005654 IBA
    nucleoplasm GO:0005654 IDA
    cytosol GO:0005829 IDA
 Experiment description of studies that identified THAP11 in exosomes
1
Experiment ID 207
MISEV standards
EM
Biophysical techniques
TSG101|HSP70|FLOT1
Enriched markers
VDAC
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 208
MISEV standards
EM
Biophysical techniques
TSG101|HSP70|FLOT1
Enriched markers
VDAC
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
3
Experiment ID 209
MISEV standards
Biophysical techniques
TSG101|HSP70|FLOT1
Enriched markers
VDAC
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for THAP11
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UBE2H 7328
Affinity Capture-MS Homo sapiens
2 KRT37 8688
Affinity Capture-MS Homo sapiens
3 NCKAP5L  
Affinity Capture-MS Homo sapiens
4 CCDC132 55610
Affinity Capture-MS Homo sapiens
5 GIT2 9815
Affinity Capture-MS Homo sapiens
6 C9orf78 51759
Affinity Capture-MS Homo sapiens
7 GRIPAP1 56850
Affinity Capture-MS Homo sapiens
8 RABGAP1L 9910
Affinity Capture-MS Homo sapiens
9 ARNTL  
Affinity Capture-MS Homo sapiens
10 THAP11 57215
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
11 RNH1 6050
Affinity Capture-MS Homo sapiens
12 WTAP 9589
Affinity Capture-MS Homo sapiens
13 SKA1  
Affinity Capture-MS Homo sapiens
14 EXOC1 55763
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
15 CASP3 836
Two-hybrid Homo sapiens
16 FBXW7  
Affinity Capture-MS Homo sapiens
17 KRT40  
Affinity Capture-MS Homo sapiens
18 PSMD9 5715
Affinity Capture-MS Homo sapiens
19 ANOS1 3730
Affinity Capture-MS Homo sapiens
20 OIP5  
Affinity Capture-MS Homo sapiens
21 SLC31A1 1317
Affinity Capture-MS Homo sapiens
22 LHFPL2 10184
Affinity Capture-MS Homo sapiens
23 ZSCAN31  
Affinity Capture-MS Homo sapiens
24 HAUS6  
Affinity Capture-MS Homo sapiens
25 FIGNL1 63979
Affinity Capture-MS Homo sapiens
26 RRP8  
Affinity Capture-MS Homo sapiens
27 VPS53 55275
Affinity Capture-MS Homo sapiens
28 MECP2 4204
Affinity Capture-MS Homo sapiens
29 PKN3 29941
Affinity Capture-MS Homo sapiens
30 KNSTRN  
Affinity Capture-MS Homo sapiens
31 PFDN6 10471
Two-hybrid Homo sapiens
32 PSME3 10197
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
33 C15orf59  
Affinity Capture-MS Homo sapiens
34 RABGEF1 27342
Affinity Capture-MS Homo sapiens
35 CAMK2A 815
Affinity Capture-MS Homo sapiens
36 S100A2 6273
Affinity Capture-MS Homo sapiens
37 THAP3  
Affinity Capture-MS Homo sapiens
38 CLOCK  
Affinity Capture-MS Homo sapiens
39 CTBP1 1487
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
40 CTBP2 1488
Affinity Capture-MS Homo sapiens
41 OGT 8473
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
42 SYNC  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
43 IL20RA  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
44 HEMGN  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
45 LRRC45  
Two-hybrid Homo sapiens
46 IKZF5 64376
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
47 TGM1 7051
Affinity Capture-MS Homo sapiens
48 HECTD1 25831
Affinity Capture-MS Homo sapiens
49 RPS16 6217
Affinity Capture-MS Homo sapiens
50 CAMKK2 10645
Affinity Capture-MS Homo sapiens
51 CEBPA  
Protein-peptide Homo sapiens
52 PIPSL 266971
Affinity Capture-MS Homo sapiens
53 RTEL1 51750
Affinity Capture-MS Homo sapiens
54 YEATS4  
Affinity Capture-MS Homo sapiens
55 TMEM52B 120939
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
56 TPX2  
Two-hybrid Homo sapiens
57 SRSF11 9295
Two-hybrid Homo sapiens
58 DZIP3  
Affinity Capture-MS Homo sapiens
59 Zwint  
Affinity Capture-MS Mus musculus
60 ECT2 1894
Two-hybrid Homo sapiens
61 Emc6  
Affinity Capture-MS Mus musculus
62 HCFC1 3054
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Reconstituted Complex Homo sapiens
Co-localization Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
63 PHLDB3  
Affinity Capture-MS Homo sapiens
64 SLX1B  
Two-hybrid Homo sapiens
65 RPRD1A  
Affinity Capture-MS Homo sapiens
66 YY1 7528
Proximity Label-MS Homo sapiens
67 TFPT  
Affinity Capture-MS Homo sapiens
68 TMEM74  
Affinity Capture-MS Homo sapiens
69 HNRNPCL2 440563
Affinity Capture-MS Homo sapiens
70 CDK2 1017
Affinity Capture-MS Homo sapiens
71 KCNE3  
Affinity Capture-MS Homo sapiens
72 NUTF2 10204
Two-hybrid Homo sapiens
73 PHF21A  
Affinity Capture-MS Homo sapiens
74 ZNF653  
Affinity Capture-MS Homo sapiens
75 DLL1  
Affinity Capture-MS Homo sapiens
76 PSMC5 5705
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
77 TUFT1  
Affinity Capture-MS Homo sapiens
78 DDRGK1 65992
Affinity Capture-MS Homo sapiens
79 PHF8  
Affinity Capture-MS Homo sapiens
80 HMG20A  
Affinity Capture-MS Homo sapiens
81 C9orf16  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
82 UMODL1  
Affinity Capture-MS Homo sapiens
83 URM1  
Affinity Capture-MS Homo sapiens
84 GSG2  
Affinity Capture-MS Homo sapiens
85 FTL 2512
Affinity Capture-MS Homo sapiens
86 TSPAN5 10098
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
87 FAM175B 23172
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
88 Ercc6l  
Affinity Capture-MS Mus musculus
89 ACTA2 59
Affinity Capture-MS Homo sapiens
90 ILF3 3609
Affinity Capture-MS Homo sapiens
91 FBXL6  
Affinity Capture-MS Homo sapiens
92 MAX  
Affinity Capture-MS Homo sapiens
93 SIN3A  
Reconstituted Complex Homo sapiens
94 CCHCR1  
Affinity Capture-MS Homo sapiens
95 Pcgf1  
Affinity Capture-MS Mus musculus
96 TRIM52  
Affinity Capture-MS Homo sapiens
97 NOL4  
Affinity Capture-MS Homo sapiens
98 SPINT2 10653
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
99 VPS52 6293
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
100 HDAC1 3065
Reconstituted Complex Homo sapiens
101 CCDC93 54520
Affinity Capture-MS Homo sapiens
102 PRDM5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
103 KRT38 8687
Affinity Capture-MS Homo sapiens
104 GOLGA5 9950
Affinity Capture-MS Homo sapiens
105 EXTL3 2137
Affinity Capture-MS Homo sapiens
106 HNRNPU 3192
Affinity Capture-MS Homo sapiens
107 PTRF 284119
Affinity Capture-MS Homo sapiens
108 CCT8L2  
Affinity Capture-MS Homo sapiens
109 RCOR1  
Affinity Capture-MS Homo sapiens
110 ZKSCAN8  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which THAP11 is involved
No pathways found





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