Gene description for TERF1
Gene name	telomeric repeat binding factor (NIMA-interacting) 1
Gene symbol	TERF1
Other names/aliases	PIN2 TRBF1 TRF TRF1 hTRF1-AS t-TRF1
Species	Homo sapiens
Database cross references - TERF1
ExoCarta	ExoCarta_7013
Entrez Gene	7013
HGNC	11728
MIM	600951
UniProt	P54274
TERF1 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells	Unpublished / Not applicable

Gene ontology annotations for TERF1

Molecular Function     microtubule binding GO:0008017 IDA     protein homodimerization activity GO:0042803 IPI     chromatin binding GO:0003682 IEA     DNA binding GO:0003677 NAS     protein heterodimerization activity GO:0046982 IDA     telomeric DNA binding GO:0042162 IDA     double-stranded telomeric DNA binding GO:0003691 IDA     DNA binding, bending GO:0008301 IDA     protein binding GO:0005515 IPI Biological Process     positive regulation of mitotic cell cycle GO:0045931 IMP     positive regulation of apoptotic process GO:0043065 IDA     mitotic spindle assembly checkpoint GO:0007094 IMP     response to drug GO:0042493 IEA     negative regulation of DNA replication GO:0008156 IDA     negative regulation of telomere maintenance via semi-conservative replication GO:0032214 NAS     protein homooligomerization GO:0051260 IDA     telomere maintenance via telomerase GO:0007004 NAS     cell division GO:0051301 IEA     telomere maintenance GO:0000723 TAS     positive regulation of mitotic nuclear division GO:0045840 IMP     negative regulation of telomerase activity GO:0051974 IGI     mitotic nuclear division GO:0007067 IEA     positive regulation of microtubule polymerization GO:0031116 IDA     telomeric loop formation GO:0031627 IBA     G2/M transition of mitotic cell cycle GO:0000086 IEP     negative regulation of telomere maintenance via telomerase GO:0032211 IGI Subcellular Localization     nuclear telomere cap complex GO:0000783 ISS     spindle GO:0005819 IEA     nucleus GO:0005634 NAS     nuclear chromosome, telomeric region GO:0000784 IBA     chromosome, telomeric region GO:0000781 IDA     cytoplasm GO:0005737 IEA     nucleoplasm GO:0005654 TAS     nucleolus GO:0005730 IDA