Gene description for DMAP1
Gene name DNA methyltransferase 1 associated protein 1
Gene symbol DMAP1
Other names/aliases DNMAP1
Species Homo sapiens
 Database cross references - DMAP1
ExoCarta ExoCarta_55929
Entrez Gene 55929
HGNC 18291
MIM 605077
UniProt Q9NPF5  
 DMAP1 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for DMAP1
Molecular Function
    chromatin binding GO:0003682 IEA
    protein binding GO:0005515 IPI
    transcription corepressor activity GO:0003714 IEA
    RNA polymerase II repressing transcription factor binding GO:0001103 IDA
Biological Process
    DNA methylation GO:0006306 TAS
    negative regulation of transcription, DNA-templated GO:0045892 NAS
    chromatin remodeling GO:0006338 IEA
    chromatin organization GO:0006325 TAS
    regulation of growth GO:0040008 IEA
    negative regulation of transcription from RNA polymerase II promoter GO:0000122 IDA
    histone H2A acetylation GO:0043968 IDA
    histone H4 acetylation GO:0043967 IDA
    positive regulation of transcription factor import into nucleus GO:0042993 IDA
    transcription, DNA-templated GO:0006351 IEA
    DNA repair GO:0006281 IEA
Subcellular Localization
    cytoplasm GO:0005737 IDA
    NuA4 histone acetyltransferase complex GO:0035267 IDA
    nucleoplasm GO:0005654 TAS
    nucleus GO:0005634 NAS
    replication fork GO:0005657 IEA
 Experiment description of studies that identified DMAP1 in exosomes
Experiment ID 217
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for DMAP1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 C19orf2  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
2 RGS6 9628
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
3 TSG101 7251
Two-hybrid Homo sapiens
4 ING1  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
5 DNMT1 1786
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
View the network image/svg+xml
 Pathways in which DMAP1 is involved
HATs acetylate histones TAS Reactome

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