Gene description for BRK1
Gene name BRICK1, SCAR/WAVE actin-nucleating complex subunit
Gene symbol BRK1
Other names/aliases C3orf10
HSPC300
MDS027
hHBrk1
Species Homo sapiens
 Database cross references - BRK1
ExoCarta ExoCarta_55845
Vesiclepedia VP_55845
Entrez Gene 55845
HGNC 23057
MIM 611183
UniProt Q8WUW1  
 BRK1 identified in exosomes derived from the following tissue/cell type
B cells 20458337    
B cells 20458337    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Mesenchymal stem cells 36408942    
Platelets 25332113    
Platelets 25332113    
Platelets 25332113    
Thymus 23844026    
 Gene ontology annotations for BRK1
Molecular Function
    protein binding GO:0005515 IPI
    small GTPase binding GO:0031267 IDA
    identical protein binding GO:0042802 IDA
    protein-containing complex binding GO:0044877 IPI
Biological Process
    in utero embryonic development GO:0001701 IEA
    actin filament organization GO:0007015 IEA
    regulation of actin polymerization or depolymerization GO:0008064 IBA
    positive regulation of lamellipodium assembly GO:0010592 IDA
    positive regulation of lamellipodium assembly GO:0010592 IMP
    Rac protein signal transduction GO:0016601 IDA
    positive regulation of protein-containing complex assembly GO:0031334 IMP
    fibroblast proliferation GO:0048144 IEA
    positive regulation of fibroblast proliferation GO:0048146 IEA
    cell motility GO:0048870 IBA
    positive regulation of Arp2/3 complex-mediated actin nucleation GO:2000601 IDA
Subcellular Localization
    cytosol GO:0005829 TAS
    cytoskeleton GO:0005856 IEA
    lamellipodium GO:0030027 ISS
    SCAR complex GO:0031209 IBA
    SCAR complex GO:0031209 IDA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified BRK1 in exosomes
1
Experiment ID 80
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
2
Experiment ID 81
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
3
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
7
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
9
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
10
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
11
Experiment ID 231
MISEV standards
✘ Biophysical techniques
✔
Alix|CD63|CD9
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 232
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 233
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for BRK1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HOMER1  
Affinity Capture-MS Homo sapiens
2 TNIP1 10318
Affinity Capture-MS Homo sapiens
3 CCSER2 54462
Affinity Capture-MS Homo sapiens
4 KLC2 64837
Affinity Capture-MS Homo sapiens
5 BLOC1S6  
Affinity Capture-MS Homo sapiens
6 CEP89 84902
Affinity Capture-MS Homo sapiens
7 HSBP1 3281
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
8 WASF2 10163
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 NUP62 23636
Affinity Capture-MS Homo sapiens
10 DTNA  
Affinity Capture-MS Homo sapiens
11 ARL14EP  
Affinity Capture-MS Homo sapiens
12 SETDB1  
Affinity Capture-MS Homo sapiens
13 STX11 8676
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
14 SNAPIN 23557
Affinity Capture-MS Homo sapiens
15 CCDC78  
Affinity Capture-MS Homo sapiens
16 BLOC1S1  
Affinity Capture-MS Homo sapiens
17 MBIP  
Affinity Capture-MS Homo sapiens
18 NDE1 54820
Affinity Capture-MS Homo sapiens
19 NCKAP1L 3071
Affinity Capture-MS Homo sapiens
20 PCNT  
Affinity Capture-MS Homo sapiens
21 PPFIA3 8541
Affinity Capture-MS Homo sapiens
22 NAV1 89796
Affinity Capture-MS Homo sapiens
23 KIF5B 3799
Affinity Capture-MS Homo sapiens
24 CCDC53 51019
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
25 ABI1 10006
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
26 NHS 4810
Affinity Capture-MS Homo sapiens
27 TIMM50 92609
Affinity Capture-MS Homo sapiens
28 NCK1 4690
Affinity Capture-MS Homo sapiens
29 WASF3 10810
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
30 EEA1 8411
Affinity Capture-MS Homo sapiens
31 PFN1 5216
Affinity Capture-MS Homo sapiens
32 PPFIA2 8499
Affinity Capture-MS Homo sapiens
33 BANP  
Affinity Capture-MS Homo sapiens
34 SDK2 54549
Affinity Capture-MS Homo sapiens
35 ARHGAP12  
Affinity Capture-MS Homo sapiens
36 CEP55 55165
Affinity Capture-MS Homo sapiens
37 WASF1 8936
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
38 RB1CC1 9821
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
39 PLEKHH1  
Affinity Capture-MS Homo sapiens
40 GHRL  
Affinity Capture-MS Homo sapiens
41 KLC4 89953
Affinity Capture-MS Homo sapiens
42 SNAP47 116841
Affinity Capture-MS Homo sapiens
43 POC1A  
Affinity Capture-MS Homo sapiens
44 ACTA1 58
Co-fractionation Homo sapiens
45 DTNBP1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
46 GCC2 9648
Affinity Capture-MS Homo sapiens
47 BLOC1S5 63915
Affinity Capture-MS Homo sapiens
48 KIF5A 3798
Affinity Capture-MS Homo sapiens
49 ANKHD1 54882
Affinity Capture-MS Homo sapiens
50 MIA3 375056
Affinity Capture-MS Homo sapiens
51 ULK1  
Affinity Capture-MS Homo sapiens
52 BRAP  
Two-hybrid Homo sapiens
53 ACTG1 71
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
54 SRCIN1  
Affinity Capture-MS Homo sapiens
55 DISC1 27185
Affinity Capture-MS Homo sapiens
56 RNF40 9810
Affinity Capture-MS Homo sapiens
57 CNGA4  
Affinity Capture-MS Homo sapiens
58 TSSC1 7260
Affinity Capture-MS Homo sapiens
59 CYFIP2 26999
Affinity Capture-MS Homo sapiens
60 MAD1L1  
Affinity Capture-MS Homo sapiens
61 GRIPAP1 56850
Affinity Capture-MS Homo sapiens
62 NCKAP1 10787
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
63 AKAP9 10142
Affinity Capture-MS Homo sapiens
64 ACTBL2 345651
Co-fractionation Homo sapiens
65 NHSL1  
Affinity Capture-MS Homo sapiens
66 DIXDC1  
Affinity Capture-MS Homo sapiens
67 Wash  
Affinity Capture-MS Mus musculus
68 FARSB 10056
Affinity Capture-MS Homo sapiens
69 COG6 57511
Affinity Capture-MS Homo sapiens
70 EPS8L1 54869
Affinity Capture-MS Homo sapiens
71 AMZ1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
72 MRFAP1  
Two-hybrid Homo sapiens
73 LOH12CR1 118426
Affinity Capture-MS Homo sapiens
74 UACA 55075
Affinity Capture-MS Homo sapiens
75 PPFIA1 8500
Affinity Capture-MS Homo sapiens
76 BAIAP2 10458
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
77 KIAA1522 57648
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
78 OST4  
Affinity Capture-MS Homo sapiens
79 CBLC  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
80 BLOC1S2 282991
Affinity Capture-MS Homo sapiens
81 ANKHD1-EIF4EBP3  
Affinity Capture-MS Homo sapiens
82 ATG13 9776
Affinity Capture-MS Homo sapiens
83 PFDN1 5201
Two-hybrid Homo sapiens
84 ODF2L  
Affinity Capture-MS Homo sapiens
85 ATG101  
Affinity Capture-MS Homo sapiens
86 CENPF 1063
Affinity Capture-MS Homo sapiens
87 RNF20 56254
Affinity Capture-MS Homo sapiens
88 TBC1D2B 23102
Affinity Capture-MS Homo sapiens
89 KIF5C 3800
Affinity Capture-MS Homo sapiens
90 TRIP11 9321
Affinity Capture-MS Homo sapiens
91 NCK2 8440
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
92 CEP44  
Affinity Capture-MS Homo sapiens
93 C10orf32  
Affinity Capture-MS Homo sapiens
94 UBB 7314
Affinity Capture-MS Homo sapiens
95 SPG11 80208
Affinity Capture-MS Homo sapiens
96 ABI2 10152
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
97 BLOC1S4 55330
Affinity Capture-MS Homo sapiens
98 NDEL1 81565
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
99 CYFIP1 23191
Affinity Capture-MS Homo sapiens
100 NHSL2  
Affinity Capture-MS Homo sapiens
101 CCDC40  
Affinity Capture-MS Homo sapiens
102 BRI3BP 140707
Affinity Capture-MS Homo sapiens
103 ARSF 416
Affinity Capture-MS Homo sapiens
104 CDKN2A 1029
Co-fractionation Homo sapiens
View the network image/svg+xml
 Pathways in which BRK1 is involved
PathwayEvidenceSource
Disease TAS Reactome
Disease IEA Reactome
Fcgamma receptor (FCGR) dependent phagocytosis TAS Reactome
Fcgamma receptor (FCGR) dependent phagocytosis IEA Reactome
FCGR3A-mediated phagocytosis TAS Reactome
FCGR3A-mediated phagocytosis IEA Reactome
Immune System TAS Reactome
Immune System IEA Reactome
Infectious disease TAS Reactome
Infectious disease IEA Reactome
Innate Immune System TAS Reactome
Innate Immune System IEA Reactome
Leishmania infection TAS Reactome
Leishmania infection IEA Reactome
Leishmania phagocytosis TAS Reactome
Leishmania phagocytosis IEA Reactome
Parasite infection TAS Reactome
Parasite infection IEA Reactome
Parasitic Infection Pathways TAS Reactome
Parasitic Infection Pathways IEA Reactome
RAC1 GTPase cycle TAS Reactome
RAC2 GTPase cycle TAS Reactome
RAC3 GTPase cycle TAS Reactome
Regulation of actin dynamics for phagocytic cup formation TAS Reactome
Regulation of actin dynamics for phagocytic cup formation IEA Reactome
RHO GTPase cycle TAS Reactome
RHO GTPase Effectors TAS Reactome
RHO GTPase Effectors IEA Reactome
RHO GTPases Activate WASPs and WAVEs TAS Reactome
RHO GTPases Activate WASPs and WAVEs IEA Reactome
Signal Transduction TAS Reactome
Signal Transduction IEA Reactome
Signaling by Receptor Tyrosine Kinases TAS Reactome
Signaling by Rho GTPases TAS Reactome
Signaling by Rho GTPases IEA Reactome
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 TAS Reactome
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 IEA Reactome
Signaling by VEGF TAS Reactome
VEGFA-VEGFR2 Pathway TAS Reactome





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