Gene description for NUP43
Gene name nucleoporin 43kDa
Gene symbol NUP43
Other names/aliases bA350J20.1
p42
Species Homo sapiens
 Database cross references - NUP43
ExoCarta ExoCarta_348995
Vesiclepedia VP_348995
Entrez Gene 348995
HGNC 21182
MIM 608141
UniProt Q8NFH3  
 NUP43 identified in sEVs derived from the following tissue/cell type
Chondrocytes 35931686    
Chondrocytes 35931686    
Embryonic kidney cells 36706192    
Embryonic kidney cells 36706192    
Mesenchymal stem cells 36408942    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
 Gene ontology annotations for NUP43
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    nucleocytoplasmic transport GO:0006913 NAS
    chromosome segregation GO:0007059 IEA
    protein transport GO:0015031 IEA
    mRNA transport GO:0051028 IEA
    cell division GO:0051301 IEA
Subcellular Localization
    kinetochore GO:0000776 IDA
    nuclear envelope GO:0005635 IDA
    nuclear envelope GO:0005635 TAS
    nuclear pore GO:0005643 NAS
    nucleoplasm GO:0005654 IDA
    cytosol GO:0005829 IDA
    cytosol GO:0005829 TAS
    nuclear speck GO:0016607 IDA
    nuclear pore outer ring GO:0031080 IBA
    nuclear pore outer ring GO:0031080 IDA
    nuclear pore outer ring GO:0031080 NAS
 Experiment description of studies that identified NUP43 in sEVs
1
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 1275
MISEV standards
Biophysical techniques
✔
CD9|TSG101|FLOT1|FLOT2|RAB35|RAB5A|GAPDH|TFRC|CD63|Alix
Enriched markers
✔
PCNA|CANX|GAPDH|HSP90AA1|HSP90B1
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
4
Experiment ID 1280
MISEV standards
Biophysical techniques
✔
TSG101|CD9|FLOT1|FLOT2|RAB35|RAB5A|GAPDH|TFRC|CD63|Alix
Enriched markers
✔
PCNA|CANX|GAPDH|HSP90AA1|HSP90B1
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T - Fraction 5
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density 1.151 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
5
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
7
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for NUP43
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 EIF4G3 8672
Proximity Label-MS Homo sapiens
2 SLFN11 91607
Affinity Capture-MS Homo sapiens
3 RIT1 6016
Negative Genetic Homo sapiens
4 ZNF292  
Proximity Label-MS Homo sapiens
5 NCOA6  
Proximity Label-MS Homo sapiens
6 HPS5 11234
Proximity Label-MS Homo sapiens
7 ISG15 9636
Affinity Capture-MS Homo sapiens
8 HOOK1  
Proximity Label-MS Homo sapiens
9 KLC2 64837
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 CCT3 7203
Proximity Label-MS Homo sapiens
11 NUPL2 11097
Proximity Label-MS Homo sapiens
12 JMJD1C 221037
Proximity Label-MS Homo sapiens
13 HSPA6 3310
Proximity Label-MS Homo sapiens
14 Rcc1  
Affinity Capture-MS Mus musculus
15 ANXA3 306
Proximity Label-MS Homo sapiens
16 ZDHHC7  
Proximity Label-MS Homo sapiens
17 DDTL  
Proximity Label-MS Homo sapiens
18 ZNF703  
Proximity Label-MS Homo sapiens
19 KPNB1 3837
Affinity Capture-MS Homo sapiens
20 ACTC1 70
Proximity Label-MS Homo sapiens
21 ARL6IP4  
Proximity Label-MS Homo sapiens
22 XPA  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
23 GID4  
Proximity Label-MS Homo sapiens
24 UBC 7316
Affinity Capture-MS Homo sapiens
25 POM121  
Proximity Label-MS Homo sapiens
26 NETO1  
Proximity Label-MS Homo sapiens
27 CCT6B 10693
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
28 ATP8A1 10396
Proximity Label-MS Homo sapiens
29 EIF1 10209
Proximity Label-MS Homo sapiens
30 RILPL1 353116
Proximity Label-MS Homo sapiens
31 ELF4 2000
Proximity Label-MS Homo sapiens
32 PCBP3 54039
Affinity Capture-MS Homo sapiens
33 NUP160 23279
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
34 EIF4ENIF1 56478
Proximity Label-MS Homo sapiens
35 RUVBL1 8607
Proximity Label-MS Homo sapiens
36 NCOR1  
Proximity Label-MS Homo sapiens
37 C11orf30  
Proximity Label-MS Homo sapiens
38 IFT74 80173
Proximity Label-MS Homo sapiens
39 MIR1236  
Proximity Label-MS Homo sapiens
40 SENP1  
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
41 NUP153 9972
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
42 KIF5B 3799
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
43 CCDC168  
Proximity Label-MS Homo sapiens
44 PRC1 9055
Affinity Capture-MS Homo sapiens
45 MDC1  
Proximity Label-MS Homo sapiens
46 FBLN2 2199
Proximity Label-MS Homo sapiens
47 NUP93 9688
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
48 AK2 204
Proximity Label-MS Homo sapiens
49 LACE1  
Proximity Label-MS Homo sapiens
50 DCTD 1635
Proximity Label-MS Homo sapiens
51 MUC19  
Proximity Label-MS Homo sapiens
52 CAMK2B 816
Affinity Capture-MS Homo sapiens
53 PPM1A 5494
Proximity Label-MS Homo sapiens
54 ELP4  
Proximity Label-MS Homo sapiens
55 BCOR  
Proximity Label-MS Homo sapiens
56 YEATS2  
Proximity Label-MS Homo sapiens
57 NOC3L 64318
Proximity Label-MS Homo sapiens
58 TUBA1A 7846
Proximity Label-MS Homo sapiens
59 MAVS 57506
Proximity Label-MS Homo sapiens
60 SNX27 81609
Affinity Capture-MS Homo sapiens
61 DTYMK 1841
Proximity Label-MS Homo sapiens
62 PFDN6 10471
Proximity Label-MS Homo sapiens
63 CCT2 10576
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
64 UBE2V1 7335
Proximity Label-MS Homo sapiens
65 E2F4  
Affinity Capture-MS Homo sapiens
66 SRP9 6726
Proximity Label-MS Homo sapiens
67 POM121C  
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
68 TCP1 6950
Proximity Label-MS Homo sapiens
69 ATG4A  
Proximity Label-MS Homo sapiens
70 SENP2 59343
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
71 DBNL 28988
Proximity Label-MS Homo sapiens
72 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
73 SUCLG1 8802
Proximity Label-MS Homo sapiens
74 CCAR2 57805
Proximity Label-MS Homo sapiens
75 SRSF3 6428
Proximity Label-MS Homo sapiens
76 KLC4 89953
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
77 EIF2A 83939
Proximity Label-MS Homo sapiens
78 MAPRE1 22919
Affinity Capture-MS Homo sapiens
79 CCT5 22948
Proximity Label-MS Homo sapiens
80 TTF1  
Proximity Label-MS Homo sapiens
81 PFDN2 5202
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
82 CNOT1 23019
Proximity Label-MS Homo sapiens
83 MIR1292  
Proximity Label-MS Homo sapiens
84 NUP62 23636
Proximity Label-MS Homo sapiens
85 CLSTN2 64084
Affinity Capture-MS Homo sapiens
86 LUC7L2 51631
Proximity Label-MS Homo sapiens
87 BICD2 23299
Proximity Label-MS Homo sapiens
88 LAGE3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
89 AKR1A1 10327
Proximity Label-MS Homo sapiens
90 SMARCE1 6605
Proximity Label-MS Homo sapiens
91 Ube2i  
Affinity Capture-MS Mus musculus
92 AHCTF1 25909
Proximity Label-MS Homo sapiens
93 CSTB 1476
Proximity Label-MS Homo sapiens
94 NIPSNAP1 8508
Proximity Label-MS Homo sapiens
95 CD93  
Proximity Label-MS Homo sapiens
96 Nup155  
Affinity Capture-MS Mus musculus
97 SYNE2 23224
Proximity Label-MS Homo sapiens
98 LARP1 23367
Proximity Label-MS Homo sapiens
99 ZFP36L2 678
Proximity Label-MS Homo sapiens
100 BCLAF1 9774
Proximity Label-MS Homo sapiens
101 DST 667
Proximity Label-MS Homo sapiens
102 NUP37 79023
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
103 GLOD4 51031
Proximity Label-MS Homo sapiens
104 PGLS 25796
Proximity Label-MS Homo sapiens
105 FANCD2  
Affinity Capture-MS Homo sapiens
106 MAP4 4134
Proximity Label-MS Homo sapiens
107 Nup98  
Affinity Capture-MS Mus musculus
Affinity Capture-MS Mus musculus
108 EIF4G1 1981
Proximity Label-MS Homo sapiens
109 SEC13 6396
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
110 CCT6A 908
Proximity Label-MS Homo sapiens
111 RLIM 51132
Affinity Capture-MS Homo sapiens
112 HCFC1 3054
Proximity Label-MS Homo sapiens
113 NUP88 4927
Proximity Label-MS Homo sapiens
114 HSP90AB1 3326
Proximity Label-MS Homo sapiens
115 STIM1 6786
Proximity Label-MS Homo sapiens
116 EGFR 1956
Negative Genetic Homo sapiens
117 OSGEP 55644
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
118 FUS 2521
Affinity Capture-MS Homo sapiens
119 NUP214 8021
Proximity Label-MS Homo sapiens
120 EIF4G2 1982
Proximity Label-MS Homo sapiens
121 TNRC6B  
Proximity Label-MS Homo sapiens
122 UBL5 59286
Proximity Label-MS Homo sapiens
123 VBP1 7411
Proximity Label-MS Homo sapiens
124 TOX3  
Proximity Label-MS Homo sapiens
125 FSIP2 401024
Proximity Label-MS Homo sapiens
126 ARID1B 57492
Proximity Label-MS Homo sapiens
127 GRM7 2917
Proximity Label-MS Homo sapiens
128 RBM26 64062
Proximity Label-MS Homo sapiens
129 Nup107  
Affinity Capture-MS Mus musculus
Affinity Capture-MS Mus musculus
130 NME1 4830
Proximity Label-MS Homo sapiens
131 MTTP 4547
Proximity Label-MS Homo sapiens
132 RGPD5  
Affinity Capture-MS Homo sapiens
133 ZMYND8 23613
Proximity Label-MS Homo sapiens
134 HSDL2 84263
Proximity Label-MS Homo sapiens
135 PHF21A  
Proximity Label-MS Homo sapiens
136 PDZD2  
Proximity Label-MS Homo sapiens
137 ELF2  
Proximity Label-MS Homo sapiens
138 HP1BP3 50809
Proximity Label-MS Homo sapiens
139 TP53RK 112858
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
140 SPAST 6683
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
141 DDB1 1642
Affinity Capture-Western Homo sapiens
142 AHNAK2 113146
Proximity Label-MS Homo sapiens
143 RANBP1 5902
Affinity Capture-MS Homo sapiens
144 ARID1A 8289
Proximity Label-MS Homo sapiens
145 SEH1L 81929
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
146 TPRKB 51002
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
147 CCDC88A 55704
Proximity Label-MS Homo sapiens
148 HSPD1 3329
Proximity Label-MS Homo sapiens
149 ASH1L 55870
Proximity Label-MS Homo sapiens
150 CETN2 1069
Affinity Capture-Western Homo sapiens
151 BAIAP2 10458
Proximity Label-MS Homo sapiens
152 PFDN5 5204
Proximity Label-MS Homo sapiens
153 RAE1 8480
Proximity Label-MS Homo sapiens
154 ATP13A5  
Proximity Label-MS Homo sapiens
155 NKAP 79576
Proximity Label-MS Homo sapiens
156 AVPR2  
Proximity Label-MS Homo sapiens
157 SUGT1 10910
Proximity Label-MS Homo sapiens
158 FBN1 2200
Proximity Label-MS Homo sapiens
159 SALL2  
Proximity Label-MS Homo sapiens
160 RRM2 6241
Proximity Label-MS Homo sapiens
161 CCT8 10694
Proximity Label-MS Homo sapiens
162 SIRT6  
Affinity Capture-MS Homo sapiens
163 PDCL3 79031
Proximity Label-MS Homo sapiens
164 NUP133 55746
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
165 RAB3GAP2 25782
Co-fractionation Homo sapiens
166 SSFA2 6744
Proximity Label-MS Homo sapiens
167 TP53 7157
Proximity Label-MS Homo sapiens
168 MKL2  
Proximity Label-MS Homo sapiens
169 TMEM214 54867
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
170 RGPD8  
Affinity Capture-MS Homo sapiens
171 ERH 2079
Proximity Label-MS Homo sapiens
172 DNAH9  
Proximity Label-MS Homo sapiens
173 PDCL 5082
Proximity Label-MS Homo sapiens
174 DNAJA2 10294
Proximity Label-MS Homo sapiens
175 PIN1 5300
Proximity Label-MS Homo sapiens
176 RYR2 6262
Proximity Label-MS Homo sapiens
177 PSMB7 5695
Proximity Label-MS Homo sapiens
178 PRRC2C 23215
Proximity Label-MS Homo sapiens
179 COX5A 9377
Proximity Label-MS Homo sapiens
180 NGEF  
Proximity Label-MS Homo sapiens
181 USP44  
Proximity Label-MS Homo sapiens
182 DCTN2 10540
Co-fractionation Homo sapiens
183 LRP12 29967
Proximity Label-MS Homo sapiens
184 SND1 27044
Proximity Label-MS Homo sapiens
185 NUP98 4928
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
186 SMC1A 8243
Proximity Label-MS Homo sapiens
187 CCT7 10574
Affinity Capture-MS Homo sapiens
188 PSMA1 5682
Proximity Label-MS Homo sapiens
189 Nup214  
Affinity Capture-MS Mus musculus
190 NUP50 10762
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
191 NUP107 57122
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
192 TAGLN2 8407
Affinity Capture-MS Homo sapiens
193 MT1F  
Proximity Label-MS Homo sapiens
194 TCF20  
Proximity Label-MS Homo sapiens
195 RANBP2 5903
Proximity Label-MS Homo sapiens
196 LIN54  
Proximity Label-MS Homo sapiens
197 Ranbp2  
Affinity Capture-MS Mus musculus
198 LMLN  
Proximity Label-MS Homo sapiens
199 CUL7 9820
Affinity Capture-MS Homo sapiens
200 KIAA1551  
Proximity Label-MS Homo sapiens
201 NUP85 79902
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
202 PLD6  
Affinity Capture-MS Homo sapiens
203 ZNF318 24149
Proximity Label-MS Homo sapiens
204 TDRD7 23424
Proximity Label-MS Homo sapiens
205 NR1D2  
Proximity Label-MS Homo sapiens
206 TIMM13 26517
Proximity Label-MS Homo sapiens
207 CUL4A 8451
Affinity Capture-Western Homo sapiens
View the network image/svg+xml
 Pathways in which NUP43 is involved
PathwayEvidenceSource
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal TAS Reactome
Amplification of signal from the kinetochores TAS Reactome
Antiviral mechanism by IFN-stimulated genes TAS Reactome
Cell Cycle TAS Reactome
Cell Cycle IEA Reactome
Cell Cycle Checkpoints TAS Reactome
Cell Cycle, Mitotic TAS Reactome
Cell Cycle, Mitotic IEA Reactome
Cellular response to heat stress TAS Reactome
Cellular responses to stimuli TAS Reactome
Cellular responses to stress TAS Reactome
Cytokine Signaling in Immune system TAS Reactome
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) TAS Reactome
Disease TAS Reactome
Disease IEA Reactome
Disorders of transmembrane transporters TAS Reactome
EML4 and NUDC in mitotic spindle formation TAS Reactome
Export of Viral Ribonucleoproteins from Nucleus TAS Reactome
Gene expression (Transcription) TAS Reactome
Gene Silencing by RNA TAS Reactome
Glucose metabolism TAS Reactome
Glycolysis TAS Reactome
HCMV Early Events TAS Reactome
HCMV Infection TAS Reactome
HCMV Late Events TAS Reactome
HIV Infection IEA Reactome
HIV Infection TAS Reactome
HIV Life Cycle TAS Reactome
Host Interactions of HIV factors TAS Reactome
Host Interactions of HIV factors IEA Reactome
Immune System TAS Reactome
Infectious disease TAS Reactome
Infectious disease IEA Reactome
Influenza Infection TAS Reactome
Influenza Viral RNA Transcription and Replication TAS Reactome
Interactions of Rev with host cellular proteins IEA Reactome
Interactions of Rev with host cellular proteins TAS Reactome
Interactions of Vpr with host cellular proteins TAS Reactome
Interferon Signaling TAS Reactome
ISG15 antiviral mechanism TAS Reactome
Late Phase of HIV Life Cycle TAS Reactome
M Phase TAS Reactome
M Phase IEA Reactome
Metabolism TAS Reactome
Metabolism of carbohydrates TAS Reactome
Metabolism of non-coding RNA TAS Reactome
Metabolism of proteins TAS Reactome
Metabolism of proteins IEA Reactome
Metabolism of RNA TAS Reactome
Mitotic Anaphase TAS Reactome
Mitotic Anaphase IEA Reactome
Mitotic Metaphase and Anaphase TAS Reactome
Mitotic Metaphase and Anaphase IEA Reactome
Mitotic Prometaphase TAS Reactome
Mitotic Prophase TAS Reactome
Mitotic Spindle Checkpoint TAS Reactome
NEP/NS2 Interacts with the Cellular Export Machinery TAS Reactome
NS1 Mediated Effects on Host Pathways TAS Reactome
Nuclear Envelope (NE) Reassembly TAS Reactome
Nuclear Envelope (NE) Reassembly IEA Reactome
Nuclear Envelope Breakdown TAS Reactome
Nuclear import of Rev protein IEA Reactome
Nuclear Pore Complex (NPC) Disassembly TAS Reactome
Post-translational protein modification TAS Reactome
Post-translational protein modification IEA Reactome
Postmitotic nuclear pore complex (NPC) reformation TAS Reactome
Postmitotic nuclear pore complex (NPC) reformation IEA Reactome
Processing of Capped Intron-Containing Pre-mRNA TAS Reactome
Regulation of Glucokinase by Glucokinase Regulatory Protein TAS Reactome
Regulation of HSF1-mediated heat shock response TAS Reactome
Resolution of Sister Chromatid Cohesion TAS Reactome
Rev-mediated nuclear export of HIV RNA TAS Reactome
RHO GTPase Effectors TAS Reactome
RHO GTPases Activate Formins TAS Reactome
SARS-CoV Infections TAS Reactome
SARS-CoV-2 activates/modulates innate and adaptive immune responses TAS Reactome
SARS-CoV-2 Infection TAS Reactome
SARS-CoV-2-host interactions TAS Reactome
Separation of Sister Chromatids TAS Reactome
Signal Transduction TAS Reactome
Signaling by Rho GTPases TAS Reactome
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 TAS Reactome
SLC transporter disorders TAS Reactome
snRNP Assembly TAS Reactome
SUMO E3 ligases SUMOylate target proteins TAS Reactome
SUMO E3 ligases SUMOylate target proteins IEA Reactome
SUMOylation TAS Reactome
SUMOylation IEA Reactome
SUMOylation of chromatin organization proteins TAS Reactome
SUMOylation of DNA damage response and repair proteins TAS Reactome
SUMOylation of DNA replication proteins IEA Reactome
SUMOylation of DNA replication proteins TAS Reactome
SUMOylation of RNA binding proteins TAS Reactome
SUMOylation of SUMOylation proteins TAS Reactome
SUMOylation of ubiquitinylation proteins TAS Reactome
Transcriptional regulation by small RNAs TAS Reactome
Transport of Mature mRNA derived from an Intron-Containing Transcript TAS Reactome
Transport of Mature mRNA Derived from an Intronless Transcript TAS Reactome
Transport of Mature mRNAs Derived from Intronless Transcripts TAS Reactome
Transport of Mature Transcript to Cytoplasm TAS Reactome
Transport of Ribonucleoproteins into the Host Nucleus TAS Reactome
Transport of the SLBP Dependant Mature mRNA TAS Reactome
Transport of the SLBP independent Mature mRNA TAS Reactome
tRNA processing TAS Reactome
tRNA processing in the nucleus TAS Reactome
Viral Infection Pathways TAS Reactome
Viral Infection Pathways IEA Reactome
Viral Messenger RNA Synthesis TAS Reactome
Vpr-mediated nuclear import of PICs TAS Reactome





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