Gene description for CCDC93
Gene name coiled-coil domain containing 93
Gene symbol CCDC93
Other names/aliases -
Species Homo sapiens
 Database cross references - CCDC93
ExoCarta ExoCarta_54520
Vesiclepedia VP_54520
Entrez Gene 54520
HGNC 25611
UniProt Q567U6  
 CCDC93 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Mesenchymal stem cells 36408942    
Neuroblastoma cells 25944692    
Thymus 23844026    
 Gene ontology annotations for CCDC93
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    Golgi to plasma membrane transport GO:0006893 IBA
    Golgi to plasma membrane transport GO:0006893 IMP
    protein transport GO:0015031 IEA
    endocytic recycling GO:0032456 IMP
Subcellular Localization
    early endosome GO:0005769 IEA
    intracellular membrane-bounded organelle GO:0043231 IDA
 Experiment description of studies that identified CCDC93 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
7
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for CCDC93
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 MNS1 55329
Co-fractionation Homo sapiens
2 HNRNPC 3183
Affinity Capture-MS Homo sapiens
3 NUF2  
Affinity Capture-MS Homo sapiens
4 FAM167A  
Affinity Capture-MS Homo sapiens
5 YEATS4  
Affinity Capture-MS Homo sapiens
6 NCKAP5L  
Affinity Capture-MS Homo sapiens
7 CCDC132 55610
Affinity Capture-MS Homo sapiens
8 GIT2 9815
Affinity Capture-MS Homo sapiens
9 NUP62 23636
Affinity Capture-MS Homo sapiens
10 DSCR3 10311
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 GRIPAP1 56850
Affinity Capture-MS Homo sapiens
12 TUFT1  
Affinity Capture-MS Homo sapiens
13 LTN1 26046
Affinity Capture-MS Homo sapiens
14 ARNTL  
Affinity Capture-MS Homo sapiens
15 VPS29 51699
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
16 CAPZB 832
Affinity Capture-MS Homo sapiens
17 C16orf62 57020
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
18 HAUS6  
Affinity Capture-MS Homo sapiens
19 EXOC1 55763
Two-hybrid Homo sapiens
20 WHAMMP3  
Affinity Capture-MS Homo sapiens
21 COMMD9 29099
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
22 PRC1 9055
Affinity Capture-MS Homo sapiens
23 KRT40  
Two-hybrid Homo sapiens
24 CPSF7 79869
Affinity Capture-MS Homo sapiens
25 PSMD9 5715
Affinity Capture-MS Homo sapiens
26 OIP5  
Affinity Capture-MS Homo sapiens
27 WASH1 100287171
Affinity Capture-MS Homo sapiens
28 KRT31 3881
Two-hybrid Homo sapiens
29 RCC1 1104
Affinity Capture-MS Homo sapiens
30 COMMD10 51397
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
31 VPS53 55275
Affinity Capture-MS Homo sapiens
32 PKN3 29941
Affinity Capture-MS Homo sapiens
33 KNSTRN  
Affinity Capture-MS Homo sapiens
34 OR13G1  
Affinity Capture-MS Homo sapiens
35 COMMD4 54939
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
36 PSMC3 5702
Affinity Capture-MS Homo sapiens
37 STMN2  
Affinity Capture-MS Homo sapiens
38 CCDC114  
Affinity Capture-MS Homo sapiens
39 LTBR 4055
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 C15orf59  
Affinity Capture-MS Homo sapiens
41 RABGEF1 27342
Affinity Capture-MS Homo sapiens
42 PDK1 5163
Affinity Capture-MS Homo sapiens
43 TMEM248 55069
Affinity Capture-MS Homo sapiens
44 COMMD7 149951
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
45 VPS51 738
Affinity Capture-MS Homo sapiens
46 NTRK1 4914
Affinity Capture-MS Homo sapiens
47 JADE2 23338
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
48 ZIC4  
Affinity Capture-MS Homo sapiens
49 CCDC22 28952
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
50 KIAA1033 23325
Affinity Capture-MS Homo sapiens
51 COMMD3 23412
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
52 ANLN 54443
Affinity Capture-MS Homo sapiens
53 NOTCH2NL 388677
Two-hybrid Homo sapiens
54 FAM45A 404636
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
55 Ranbp1 19385
Affinity Capture-MS Mus musculus
56 TSSC1 7260
Affinity Capture-MS Homo sapiens
57 COMMD2 51122
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
58 DHX36 170506
Affinity Capture-MS Homo sapiens
59 COMMD8 54951
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
60 TRAF3IP1 26146
Two-hybrid Homo sapiens
61 PHLDB3  
Affinity Capture-MS Homo sapiens
62 RPRD1A  
Affinity Capture-MS Homo sapiens
63 TFPT  
Affinity Capture-MS Homo sapiens
64 PACSIN3 29763
Affinity Capture-MS Homo sapiens
65 CNKSR3 154043
Affinity Capture-MS Homo sapiens
66 JUN 3725
Affinity Capture-MS Homo sapiens
67 COMMD6 170622
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
68 PHF21A  
Affinity Capture-MS Homo sapiens
69 FAM21C 253725
Affinity Capture-Western Homo sapiens
70 RABGAP1L 9910
Affinity Capture-MS Homo sapiens
71 HMG20A  
Affinity Capture-MS Homo sapiens
72 KIF2B 84643
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
73 COMMD1 150684
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
74 GOLGB1 2804
Affinity Capture-MS Homo sapiens
75 DZIP3  
Affinity Capture-MS Homo sapiens
76 MAX  
Affinity Capture-MS Homo sapiens
77 CCHCR1  
Affinity Capture-MS Homo sapiens
78 LINC00839  
Protein-RNA Homo sapiens
79 FXR1 8087
Affinity Capture-MS Homo sapiens
80 COMMD5 28991
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
81 THAP11 57215
Affinity Capture-MS Homo sapiens
82 DDX58 23586
Affinity Capture-RNA Homo sapiens
83 COMMD3-BMI1 100532731
Affinity Capture-MS Homo sapiens
84 KDM1A 23028
Affinity Capture-MS Homo sapiens
85 Mbd2  
Affinity Capture-MS Mus musculus
86 EZH2  
Affinity Capture-MS Homo sapiens
87 KRT38 8687
Affinity Capture-MS Homo sapiens
88 GOLGA5 9950
Affinity Capture-MS Homo sapiens
89 CLOCK  
Affinity Capture-MS Homo sapiens
90 ZUFSP 221302
Affinity Capture-MS Homo sapiens
91 PTRF 284119
Affinity Capture-MS Homo sapiens
92 RCOR1  
Affinity Capture-MS Homo sapiens
93 RANGAP1 5905
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which CCDC93 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here