Gene description for TXLNA
Gene name taxilin alpha
Gene symbol TXLNA
Other names/aliases IL14
TXLN
Species Homo sapiens
 Database cross references - TXLNA
ExoCarta ExoCarta_200081
Entrez Gene 200081
HGNC 30685
MIM 608676
UniProt P40222  
 TXLNA identified in exosomes derived from the following tissue/cell type
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
 Gene ontology annotations for TXLNA
Molecular Function
    protein binding GO:0005515 IPI
    cytokine activity GO:0005125 NAS
    syntaxin binding GO:0019905 IEA
    high molecular weight B cell growth factor receptor binding GO:0030372 NAS
Biological Process
    exocytosis GO:0006887 IEA
    B cell activation GO:0042113 IEA
    cell proliferation GO:0008283 NAS
    activation of mitophagy in response to mitochondrial depolarization GO:0098779 IMP
Subcellular Localization
    cytoplasm GO:0005737 IDA
    membrane GO:0016020 IDA
    extracellular region GO:0005576 NAS
 Experiment description of studies that identified TXLNA in exosomes
1
Experiment ID 207
ISEV standards
EM
EV Biophysical techniques
TSG101|HSP70
EV Cytosolic markers
FLOT1
EV Membrane markers
VDAC
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ.
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 208
ISEV standards
EM
EV Biophysical techniques
TSG101|HSP70
EV Cytosolic markers
FLOT1
EV Membrane markers
VDAC
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ.
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
3
Experiment ID 209
ISEV standards
EV Biophysical techniques
TSG101|HSP70
EV Cytosolic markers
FLOT1
EV Membrane markers
VDAC
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ.
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for TXLNA
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 STX1A 6804
Invitro Homo sapiens
2 STX4 6810
Invitro Homo sapiens
3 RGS20 8601
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which TXLNA is involved
No pathways found





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