Gene description for DTNB
Gene name dystrobrevin, beta
Gene symbol DTNB
Other names/aliases -
Species Homo sapiens
 Database cross references - DTNB
ExoCarta ExoCarta_1838
Vesiclepedia VP_1838
Entrez Gene 1838
HGNC 3058
MIM 602415
UniProt O60941  
 DTNB identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for DTNB
Molecular Function
    protein binding GO:0005515 IPI
    zinc ion binding GO:0008270 IEA
Biological Process
    neuron differentiation GO:0030182 IMP
    synaptic signaling GO:0099536 IBA
Subcellular Localization
    nucleus GO:0005634 IDA
    cytoplasm GO:0005737 IDA
    plasma membrane GO:0005886 IBA
    basal plasma membrane GO:0009925 IEA
    postsynaptic density GO:0014069 ISS
    dendrite GO:0030425 IEA
    synapse GO:0045202 IBA
    inhibitory synapse GO:0060077 ISS
 Experiment description of studies that identified DTNB in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for DTNB
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 TNS1 7145
Affinity Capture-MS Homo sapiens
2 UTRN 7402
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 FAM167A  
Two-hybrid Homo sapiens
4 SCGN  
Affinity Capture-MS Homo sapiens
5 CTBP2 1488
Two-hybrid Homo sapiens
6 BEGAIN  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
7 SPERT  
Two-hybrid Homo sapiens
8 NUP62 23636
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
9 DTNA  
Affinity Capture-MS Homo sapiens
10 PLEKHA2 59339
Affinity Capture-MS Homo sapiens
11 PMF1  
Affinity Capture-MS Homo sapiens
12 TRIM54  
Two-hybrid Homo sapiens
13 CCDC88B 283234
Two-hybrid Homo sapiens
14 IFT74 80173
Affinity Capture-MS Homo sapiens
15 LIN7B  
Affinity Capture-MS Homo sapiens
16 KIF5B 3799
Reconstituted Complex Homo sapiens
17 KRT40  
Two-hybrid Homo sapiens
18 ZGPAT  
Affinity Capture-MS Homo sapiens
19 ABI1 10006
Two-hybrid Homo sapiens
20 DMD 1756
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
21 MTUS2 23281
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
22 KRT31 3881
Two-hybrid Homo sapiens
23 GGA1 26088
Two-hybrid Homo sapiens
24 NOS1  
Affinity Capture-MS Homo sapiens
25 GOLGA4  
Affinity Capture-MS Homo sapiens
26 FSD2 123722
Two-hybrid Homo sapiens
27 CPNE5 57699
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
28 KCNA4  
Affinity Capture-MS Homo sapiens
29 CASK 8573
Affinity Capture-MS Homo sapiens
30 SNTG2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
31 AMOTL2 51421
Two-hybrid Homo sapiens
32 PPFIA1 8500
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
33 CEP55 55165
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
34 TRIM37  
Two-hybrid Homo sapiens
35 SNTA1 6640
Affinity Capture-MS Homo sapiens
36 DTNBP1  
Two-hybrid Homo sapiens
37 POU6F2  
Two-hybrid Homo sapiens
38 MB21D2  
Two-hybrid Homo sapiens
39 CARM1 10498
Affinity Capture-MS Homo sapiens
40 KIF5A 3798
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
41 SNTG1  
Affinity Capture-MS Homo sapiens
42 PNMA2  
Affinity Capture-MS Homo sapiens
43 CCDC101  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
44 PRKAR1B  
Two-hybrid Homo sapiens
45 LINC00238  
Two-hybrid Homo sapiens
46 SNTB1 6641
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
47 VCP 7415
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
48 DTNB 1838
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
49 ABI3 51225
Two-hybrid Homo sapiens
50 TSACC  
Two-hybrid Homo sapiens
51 CEP63  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
52 KRT33B 3884
Two-hybrid Homo sapiens
53 KRT35 3886
Two-hybrid Homo sapiens
54 TNS3 64759
Affinity Capture-MS Homo sapiens
55 KRT27 342574
Two-hybrid Homo sapiens
56 KRT15 3866
Two-hybrid Homo sapiens
57 HIST1H1B 3009
Cross-Linking-MS (XL-MS) Homo sapiens
58 COG6 57511
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
59 SPZ1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
60 CCDC85B  
Two-hybrid Homo sapiens
61 TRIM27  
Two-hybrid Homo sapiens
62 TNS2 23371
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
63 RHPN1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
64 USHBP1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
65 HMG20A  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
66 FLOT1 10211
Proximity Label-MS Homo sapiens
67 TXLNA 200081
Two-hybrid Homo sapiens
68 TRAF2 7186
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
69 CCHCR1  
Two-hybrid Homo sapiens
70 VPS52 6293
Two-hybrid Homo sapiens
71 AJUBA  
Affinity Capture-MS Homo sapiens
72 PRTFDC1 56952
Two-hybrid Homo sapiens
73 FYCO1 79443
Affinity Capture-MS Homo sapiens
74 C15orf59  
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
75 PPFIBP2 8495
Two-hybrid Homo sapiens
76 SSBP3  
Two-hybrid Homo sapiens
77 ABI2 10152
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
78 GAPDH 2597
Co-fractionation Homo sapiens
79 Tipin  
Affinity Capture-MS Mus musculus
80 KRT38 8687
Two-hybrid Homo sapiens
81 ZBTB9  
Two-hybrid Homo sapiens
82 OLFM2  
Affinity Capture-MS Homo sapiens
83 NDEL1 81565
Two-hybrid Homo sapiens
84 ZUFSP 221302
Affinity Capture-MS Homo sapiens
85 CCDC136  
Two-hybrid Homo sapiens
86 CCDC96  
Affinity Capture-MS Homo sapiens
87 CCDC67  
Two-hybrid Homo sapiens
88 SNTB2 6645
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
89 LURAP1  
Two-hybrid Homo sapiens
90 TAGAP  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which DTNB is involved
No pathways found





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